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Protein

Antitermination protein Q homolog from lambdoid prophage DLP12

Gene

quuD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Positively regulate expression of some phage genes. Bacterial host RNA polymerase modified by antitermination proteins transcribes through termination sites that otherwise prevent expression of the regulated genes (By similarity).By similarity

GO - Molecular functioni

  • DNA binding Source: EcoCyc

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription antitermination, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G6307-MONOMER.
ECOL316407:JW0539-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Antitermination protein Q homolog from lambdoid prophage DLP12
Gene namesi
Name:quuD
Synonyms:ybcQ
Ordered Locus Names:b0551, JW0539
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13633. quuD.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 127127Antitermination protein Q homolog from lambdoid prophage DLP12PRO_0000073891Add
BLAST

Proteomic databases

PaxDbiQ47274.

Interactioni

Protein-protein interaction databases

BioGridi4260894. 131 interactions.
IntActiQ47274. 4 interactions.
STRINGi511145.b0551.

Structurei

3D structure databases

ProteinModelPortaliQ47274.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105HRS. Bacteria.
ENOG4111PZ9. LUCA.
HOGENOMiHOG000119341.
OMAiQKEPINI.
OrthoDBiEOG6CK7PG.

Family and domain databases

InterProiIPR010534. Phage_933W_GpQ.
[Graphical view]
PfamiPF06530. Phage_antitermQ. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q47274-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRDIQMVLER WGAWAANNHE DVTWSSIAAG FKGLITSKVK SRPQCCDDDA
60 70 80 90 100
MIICGCMARL KKNNSDLHDL LVDYYVVGMT FMSLAGKHCC SDGYIGKRLQ
110 120
KAEGIIEGML MALDIRLEMD IVVNNSN
Length:127
Mass (Da):14,176
Last modified:November 1, 1996 - v1
Checksum:i78745EF077D6475F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92587 Genomic DNA. Translation: CAA63324.1.
U82598 Genomic DNA. Translation: AAB40747.1.
U00096 Genomic DNA. Translation: AAC73652.1.
AP009048 Genomic DNA. Translation: BAE76327.1.
PIRiS66593.
RefSeqiNP_415083.1. NC_000913.3.
WP_001204791.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73652; AAC73652; b0551.
BAE76327; BAE76327; BAE76327.
GeneIDi945177.
KEGGiecj:JW0539.
eco:b0551.
PATRICi32116266. VBIEscCol129921_0573.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X92587 Genomic DNA. Translation: CAA63324.1.
U82598 Genomic DNA. Translation: AAB40747.1.
U00096 Genomic DNA. Translation: AAC73652.1.
AP009048 Genomic DNA. Translation: BAE76327.1.
PIRiS66593.
RefSeqiNP_415083.1. NC_000913.3.
WP_001204791.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47274.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260894. 131 interactions.
IntActiQ47274. 4 interactions.
STRINGi511145.b0551.

Proteomic databases

PaxDbiQ47274.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73652; AAC73652; b0551.
BAE76327; BAE76327; BAE76327.
GeneIDi945177.
KEGGiecj:JW0539.
eco:b0551.
PATRICi32116266. VBIEscCol129921_0573.

Organism-specific databases

EchoBASEiEB3397.
EcoGeneiEG13633. quuD.

Phylogenomic databases

eggNOGiENOG4105HRS. Bacteria.
ENOG4111PZ9. LUCA.
HOGENOMiHOG000119341.
OMAiQKEPINI.
OrthoDBiEOG6CK7PG.

Enzyme and pathway databases

BioCyciEcoCyc:G6307-MONOMER.
ECOL316407:JW0539-MONOMER.

Miscellaneous databases

PROiQ47274.

Family and domain databases

InterProiIPR010534. Phage_933W_GpQ.
[Graphical view]
PfamiPF06530. Phage_antitermQ. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82."
    Mahdi A.A., Sharples G.J., Mandal T.N., Lloyd R.G.
    J. Mol. Biol. 257:561-573(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiREQ1_ECOLI
AccessioniPrimary (citable) accession number: Q47274
Secondary accession number(s): Q2MBM9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 13, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Encoded by the cryptic lambdoid prophage DLP12.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.