ID   G6PI2_RALEJ             Reviewed;         542 AA.
AC   Q471B8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 27.
DE   RecName: Full=Glucose-6-phosphate isomerase 2;
DE            Short=GPI 2;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase 2;
DE            Short=PGI 2;
DE   AltName: Full=Phosphohexose isomerase 2;
DE            Short=PHI 2;
GN   Name=pgi2; OrderedLocusNames=Reut_A1649;
OS   Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M.,
RA   Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000090; AAZ61015.1; -; Genomic_DNA.
DR   RefSeq; YP_295859.1; -.
DR   GeneID; 3610248; -.
DR   GenomeReviews; CP000090_GR; Reut_A1649.
DR   KEGG; reu:Reut_A1649; -.
DR   NMPDR; fig|264198.3.peg.2091; -.
DR   HOGENOM; Q471B8; -.
DR   OMA; Q471B8; FDGRAIT.
DR   BioCyc; REUT264198:REUT_A1649-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; 1.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    542       Glucose-6-phosphate isomerase 2.
FT                                /FTId=PRO_0000230930.
FT   ACT_SITE    353    353       Proton donor (By similarity).
FT   ACT_SITE    384    384       By similarity.
FT   ACT_SITE    505    505       By similarity.
SQ   SEQUENCE   542 AA;  59420 MW;  66588D86F2F0CC0F CRC64;
     MSTSLSAWQS LREHAAKIRH THMRDWFTGP QGQARSVRLT VEACGLTLDY AKNRVTEDTL
     SLLFALARQA RVCERRDAMF AGEPVNTTER RAALHMALRA HPGDGYRALG VPVEADVSAV
     LAQMERFARD VRSGSWTGFD GRAITDVVNI GIGGSDLGPR MVCRALEQDT EPGPRLHFVA
     NVDGYDLART LARLDAATTL VIVCSKTFTT LETMANARTA RDWFLRHGVT HSDLARHFVA
     VSTNRDAVAA FGIDPVNMFP FWDWVGGRFS LWSAVGLSIA VAIGFDRFRQ LLDGARAMDR
     HFAGAPPEQN LPMILGLLDV WYRSFLGTAS RCVAPYCEPL DLLPAFLQQL EMESNGKSVQ
     HDGAALEAGS AAVVWGTTGT NGQHAYFQMV HQGSQLVPVD FIACLQPHSD LPGHHTKLLA
     NCFAQGEALL RGRTADEVRA EGKADEALVP HLVFEGNRPS NTLLLQRLDA FHLGALLAMS
     EHRTFVQGAL WNINPFDQWG VELGKMLARP IERELEGAPP QPHDASTAAL IRRAAQFCAS
     TD
//