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Protein

Putative truncated flagellar export/assembly protein LfhA

Gene

lfhA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:G6113-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative truncated flagellar export/assembly protein LfhACurated
Gene namesi
Name:lfhA1 Publication
Synonyms:fhiA1 Publication
Ordered Locus Names:b0229, JW5811
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13144. lfhA.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei86 – 10621HelicalSequence analysisAdd
BLAST
Transmembranei124 – 14421HelicalSequence analysisAdd
BLAST
Transmembranei177 – 19721HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 579579Putative truncated flagellar export/assembly protein LfhAPRO_0000190008Add
BLAST

Proteomic databases

PRIDEiQ47153.

Interactioni

Protein-protein interaction databases

DIPiDIP-9600N.
IntActiQ47153. 6 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ47153.
SMRiQ47153. Positions 241-578.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000254014.
InParanoidiQ47153.
OMAiIIVTRIN.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PRINTSiPR00949. TYPE3IMAPROT.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q47153-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRSDLLTL LTINFIVVTK GAERISEVSA RFTLDAMPGK QMAIDADLNA
60 70 80 90 100
GLINQAQAQT RRKDVASEAD FYGAMDGASK FVRGDAIAGM MILAINLIGG
110 120 130 140 150
VCIGIFKYNL SADAAFQQYV LMTIGDGLVA QIPSLLLSTA AAIIVTRVSD
160 170 180 190 200
NGDIAHDVRN QLLASPSVLY TATGIMFVLA VVPGMPHLPF LLFSALLGFT
210 220 230 240 250
GWRMSKQPLA AEAEEKSLET LTRTITETSE QQVSWETIPL IEPISLSLGY
260 270 280 290 300
KLVALVDKAQ GNPLTQRIRG VRQVISDGNG VLLPEIRIRE NFRLKPSQYA
310 320 330 340 350
IFINGIKADE ADIPADKLMA LPSSETYGEI DGVQGNDPAY GMPVTWIQAA
360 370 380 390 400
QKAKALNMGY QVIDSASVIA THVNKIVRSY IPDLFNYDDI TQLHNRLSST
410 420 430 440 450
APRLAEDLSA ALNYSQLLKV YRALLTEGVS LRDIVTIATV LVASSTVTKD
460 470 480 490 500
HILLAADVRL ALRRSITHPF VRKQELTVYT LNNELENLLT NVVNQAQQGG
510 520 530 540 550
KVMLDSVPVD PNMLNQFQST MPQVKEQMKA AGKDPVLLVP PQLRPLLARY
560 570
ARLFAPGLHV LSYNEVPDEL ELKIMGALM
Length:579
Mass (Da):63,153
Last modified:November 1, 1997 - v1
Checksum:iC55FFA76C79F2149
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA. Translation: BAA07591.1.
U70214 Genomic DNA. Translation: AAB08649.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. No translation available.
PIRiF64747.
RefSeqiWP_001334802.1. NZ_LN832404.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38582 Genomic DNA. Translation: BAA07591.1.
U70214 Genomic DNA. Translation: AAB08649.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. No translation available.
PIRiF64747.
RefSeqiWP_001334802.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ47153.
SMRiQ47153. Positions 241-578.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-9600N.
IntActiQ47153. 6 interactions.

Proteomic databases

PRIDEiQ47153.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

EchoBASEiEB2938.
EcoGeneiEG13144. lfhA.

Phylogenomic databases

HOGENOMiHOG000254014.
InParanoidiQ47153.
OMAiIIVTRIN.

Enzyme and pathway databases

BioCyciEcoCyc:G6113-MONOMER.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PRINTSiPR00949. TYPE3IMAPROT.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "dinP, a new gene in Escherichia coli, whose product shows similarities to UmuC and its homologues."
    Ohmori H., Hatada E., Qiao Y., Tsuji M., Fukuda R.
    Mutat. Res. 347:1-7(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  2. "Systematic sequencing of the Escherichia coli genome: analysis of the 4.0 - 6.0 min (189,987 - 281,416bp) region."
    Takemoto K., Mori H., Murayama N., Kataoka K., Yano M., Itoh T., Yamamoto Y., Inokuchi H., Miki T., Hatada E., Fukuda R., Ichihara S., Mizuno T., Makino K., Nakata A., Yura T., Sampei G., Mizobuchi K.
    Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  3. "Sequence of minutes 4-25 of Escherichia coli."
    Chung E., Allen E., Araujo R., Aparicio A.M., Davis K., Duncan M., Federspiel N., Hyman R., Kalman S., Komp C., Kurdi O., Lew H., Lin D., Namath A., Oefner P., Roberts D., Schramm S., Davis R.W.
    Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  5. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  6. "The Flag-2 locus, an ancestral gene cluster, is potentially associated with a novel flagellar system from Escherichia coli."
    Ren C.-P., Beatson S.A., Parkhill J., Pallen M.J.
    J. Bacteriol. 187:1430-1440(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION AS A PSEUDOGENE.
    Strain: K12.

Entry informationi

Entry nameiLFHA_ECOLI
AccessioniPrimary (citable) accession number: Q47153
Secondary accession number(s): Q47681
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 14, 2015
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene. Promoterless gene that is a remnant of an ancestral flagellar gene cluster, Flag-2. The N-terminus is shorter than in orthologs.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.