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Protein

Transcriptional activator FeaR

Gene

feaR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi216 – 235H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

  • bacterial-type proximal promoter sequence-specific DNA binding Source: EcoCyc
  • DNA binding transcription factor activity Source: EcoCyc
  • glyoxalase III activity Source: GO_Central

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6706-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator FeaR
Gene namesi
Name:feaR
Synonyms:maoB, maoR, ydbM
Ordered Locus Names:b1384, JW1379
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13422 feaR

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945131 – 301Transcriptional activator FeaRAdd BLAST301

Proteomic databases

PaxDbiQ47129
PRIDEiQ47129

Interactioni

Protein-protein interaction databases

BioGridi4262991, 7 interactors
IntActiQ47129, 3 interactors
STRINGi316385.ECDH10B_1509

Structurei

3D structure databases

ProteinModelPortaliQ47129
SMRiQ47129
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108WFR Bacteria
COG2207 LUCA
HOGENOMiHOG000294467
InParanoidiQ47129
KOiK14063
OMAiMPTELST
PhylomeDBiQ47129

Family and domain databases

InterProiView protein in InterPro
IPR035418 AraC_binding_2
IPR009057 Homeobox-like_sf
IPR037923 HTH-like
IPR018060 HTH_AraC
IPR020449 Tscrpt_reg_HTH_AraC-type
PfamiView protein in Pfam
PF14525 AraC_binding_2, 1 hit
PF12833 HTH_18, 1 hit
PRINTSiPR00032 HTHARAC
SMARTiView protein in SMART
SM00342 HTH_ARAC, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF51215 SSF51215, 1 hit
PROSITEiView protein in PROSITE
PS01124 HTH_ARAC_FAMILY_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q47129-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPAVDNEFQ QWLSQINQVC GNFTGRLLTE RYTGVLDTHF AKGLKLSTVT
60 70 80 90 100
TSGVNLSRTW QEVKGSDDAW FYTVFQLSGQ AIMEQDERQV QIGAGDITLL
110 120 130 140 150
DASRPCSLYW QESSKQISLL LPRTLLEQYF PHQKPICAER LDADLPMVQL
160 170 180 190 200
SHRLLQESMN NPALSETESE AALQAMVCLL RPVLHQRESV QPRRERQFQK
210 220 230 240 250
VVTLIDDNIR EEILRPEWIA GETGMSVRSL YRMFADKGLV VAQYIRNRRL
260 270 280 290 300
DFCADAIRHA ADDEKLAGIG FHWGFSDQSH FSTVFKQRFG MTPGEYRRKF

R
Length:301
Mass (Da):34,620
Last modified:November 1, 1997 - v1
Checksum:iBCB0B2CC67CEF652
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D67041 Genomic DNA Translation: BAA11058.1
X99402 Genomic DNA Translation: CAA67779.1
U00096 Genomic DNA Translation: AAC74466.1
AP009048 Genomic DNA Translation: BAE76422.1
X97453 Genomic DNA Translation: CAA66105.1
PIRiC64889
RefSeqiNP_415902.1, NC_000913.3
WP_001067514.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC74466; AAC74466; b1384
BAE76422; BAE76422; BAE76422
GeneIDi945941
KEGGiecj:JW1379
eco:b1384
PATRICifig|1411691.4.peg.888

Similar proteinsi

Entry informationi

Entry nameiFEAR_ECOLI
AccessioniPrimary (citable) accession number: Q47129
Secondary accession number(s): Q2MBD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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