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Protein

Transcriptional activator FeaR

Gene

feaR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi216 – 235H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:G6706-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional activator FeaR
Gene namesi
Name:feaR
Synonyms:maoB, maoR, ydbM
Ordered Locus Names:b1384, JW1379
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13422. feaR.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945131 – 301Transcriptional activator FeaRAdd BLAST301

Proteomic databases

PaxDbiQ47129.
PRIDEiQ47129.

Interactioni

Protein-protein interaction databases

BioGridi4262991. 7 interactors.
IntActiQ47129. 3 interactors.
STRINGi316385.ECDH10B_1509.

Structurei

3D structure databases

ProteinModelPortaliQ47129.
SMRiQ47129.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108WFR. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000294467.
InParanoidiQ47129.
KOiK14063.
PhylomeDBiQ47129.

Family and domain databases

InterProiView protein in InterPro
IPR035418. AraC_binding_2.
IPR009057. Homeobox-like_sf.
IPR018060. HTH_AraC.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF14525. AraC_binding_2. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS01124. HTH_ARAC_FAMILY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q47129-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPAVDNEFQ QWLSQINQVC GNFTGRLLTE RYTGVLDTHF AKGLKLSTVT
60 70 80 90 100
TSGVNLSRTW QEVKGSDDAW FYTVFQLSGQ AIMEQDERQV QIGAGDITLL
110 120 130 140 150
DASRPCSLYW QESSKQISLL LPRTLLEQYF PHQKPICAER LDADLPMVQL
160 170 180 190 200
SHRLLQESMN NPALSETESE AALQAMVCLL RPVLHQRESV QPRRERQFQK
210 220 230 240 250
VVTLIDDNIR EEILRPEWIA GETGMSVRSL YRMFADKGLV VAQYIRNRRL
260 270 280 290 300
DFCADAIRHA ADDEKLAGIG FHWGFSDQSH FSTVFKQRFG MTPGEYRRKF

R
Length:301
Mass (Da):34,620
Last modified:November 1, 1997 - v1
Checksum:iBCB0B2CC67CEF652
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D67041 Genomic DNA. Translation: BAA11058.1.
X99402 Genomic DNA. Translation: CAA67779.1.
U00096 Genomic DNA. Translation: AAC74466.1.
AP009048 Genomic DNA. Translation: BAE76422.1.
X97453 Genomic DNA. Translation: CAA66105.1.
PIRiC64889.
RefSeqiNP_415902.1. NC_000913.3.
WP_001067514.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC74466; AAC74466; b1384.
BAE76422; BAE76422; BAE76422.
GeneIDi945941.
KEGGiecj:JW1379.
eco:b1384.
PATRICifig|1411691.4.peg.888.

Similar proteinsi

Entry informationi

Entry nameiFEAR_ECOLI
AccessioniPrimary (citable) accession number: Q47129
Secondary accession number(s): Q2MBD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene