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Q46ZY4 (Q46ZY4_CUPPJ) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site351Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2531Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1301Substrate By similarity HAMAP-Rule MF_01201
Binding site3051Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue351N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q46ZY4 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: D57773F8C31BC888

FASTA37340,142
        10         20         30         40         50         60 
MPRPIHAVIH QPAIANNLEV VRRHAPGSRV WAVIKANAYG HGIRRVFAGL RGTDGFGLLD 

        70         80         90        100        110        120 
LNEAVQLRDL GWQGPILLLE GFFQPQDVPL LEQYRLTTAV HCDEQLRMLE SARPKGPLAI 

       130        140        150        160        170        180 
QLKLNTGMNR LGFHPSQYRT AWERARAMPC VGSIVHMTHF SDADTPRGIA HQIEAFDKAT 

       190        200        210        220        230        240 
ANLPGEASLS NSAAVLWHPE AHRAWVRPGV ILYGASPTGR EADIAGVGLQ PAMSLHSELI 

       250        260        270        280        290        300 
AVQDLQPGDT VGYGSMFTAD RPMRIGVVAC GYADGYPRHA TGWGEHRAPV LVDGVRTQLV 

       310        320        330        340        350        360 
GRVSMDMLCV DLGPCPKARI GSPVTLWGQG LPIDDVAQAS GTVGYELMCA LAPRVPTTVA 

       370 
TITAPDSASP LLA 

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References

[1]"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000090 Genomic DNA. Translation: AAZ61299.1.
RefSeqYP_296143.1. NC_007347.1.

3D structure databases

ProteinModelPortalQ46ZY4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264198.Reut_A1934.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ61299; AAZ61299; Reut_A1934.
GeneID3610916.
KEGGreu:Reut_A1934.
PATRIC20229423. VBIRalEut24049_2569.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031446.
KOK01775.
OMAYGHGLER.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycCPIN264198:GIW3-1955-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ46ZY4_CUPPJ
AccessionPrimary (citable) accession number: Q46ZY4
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: July 9, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)