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Q46ZW8 (Q46ZW8_CUPPJ) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length528 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Acetyl-CoA + H2O + glyoxylate = (S)-malate + CoA. RuleBase RU000555

Pathway

Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2. RuleBase RU000555

Sequence similarities

Belongs to the malate synthase family. RuleBase RU000555

Ontologies

Keywords
   Biological processGlyoxylate bypass RuleBase RU000555
Tricarboxylic acid cycle RuleBase RU000555
   Molecular functionAcyltransferase EMBL AAZ61315.1
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglyoxylate cycle

Inferred from electronic annotation. Source: UniProtKB-UniPathway

tricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionmalate synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1631Proton acceptor By similarity PIRSR PIRSR001363-1
Active site4451Proton donor By similarity PIRSR PIRSR001363-1

Sequences

Sequence LengthMass (Da)Tools
Q46ZW8 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 1115470214238841

FASTA52859,104
        10         20         30         40         50         60 
MAITLPAGMT ITGEILPAYE DILTPEALAL VDKLHRAFEP RRQELLAARV ERAKRLDAGE 

        70         80         90        100        110        120 
VPDFLPETKH IREGDWKVAP IPKALECRRV EITGPVEAKM VINAFNSGAD SYMTDFEDSN 

       130        140        150        160        170        180 
TPNWHNQMQG QVNLKAAVRR TLTLESKGKQ YKLNDKIATL QVRPRGWHLD EKHVTIDGKR 

       190        200        210        220        230        240 
VSGGIFDFAL FLVHNAKEQI ARGDGPFFYL PKMESHLEAR LWNDIFVMAQ NEIGLPQGTI 

       250        260        270        280        290        300 
KATVLIETIL AAFEMDEILY ELREHSAGLN AGRWDYIFSC IKKFKNDKNF CLADRAKVTM 

       310        320        330        340        350        360 
TAPFMRAYAL LLLKTCHYRG APAMGGMSAL IPIKNDPEKN AIAMQGIIND KKRDATDGYD 

       370        380        390        400        410        420 
GGWVAHPGLV EPAMKEFVAV LGDKPNQFEK QRPDVNVKGS DLLDFQPETP ITEGGLRMNI 

       430        440        450        460        470        480 
NVGIHYLGAW LAGNGCVPIH NLMEDAATAE ISRSQVWQWI RSPKGKLEDG TKVTAELVRK 

       490        500        510        520 
LIPEELAKVK AEVGGETKTY DRAAEIFEQM STSEDFAEFL TLPLYEEV 

« Hide

References

[1]"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000090 Genomic DNA. Translation: AAZ61315.1.
RefSeqYP_296159.1. NC_007347.1.

3D structure databases

ProteinModelPortalQ46ZW8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264198.Reut_A1951.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ61315; AAZ61315; Reut_A1951.
GeneID3611128.
KEGGreu:Reut_A1951.
PATRIC20229457. VBIRalEut24049_2586.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2225.
HOGENOMHOG000238464.
KOK01638.
OMASIWQWIR.
OrthoDBEOG69WFFX.

Enzyme and pathway databases

BioCycCPIN264198:GIW3-1972-MONOMER.
UniPathwayUPA00703; UER00720.

Family and domain databases

InterProIPR011076. Malate_synth-like.
IPR006252. Malate_synthA.
IPR001465. Malate_synthase.
IPR019830. Malate_synthase_CS.
[Graphical view]
PfamPF01274. Malate_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF001363. Malate_synth. 1 hit.
SUPFAMSSF51645. SSF51645. 1 hit.
TIGRFAMsTIGR01344. malate_syn_A. 1 hit.
PROSITEPS00510. MALATE_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ46ZW8_CUPPJ
AccessionPrimary (citable) accession number: Q46ZW8
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: June 11, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)