Q46Z37 (MURI_CUPPJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	Reut_A2233

Organism

Cupriavidus pinatubonensis (strain JMP134 / LMG 1197) (Alcaligenes eutrophus) (Ralstonia eutropha) [Complete proteome] [HAMAP]

Taxonomic identifier

264198 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 272	272	Glutamate racemase HAMAP MF_00258		PRO_1000047600

Sequences

	Sequence		Length	Mass (Da)
	Q46Z37 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 81B4F399AFF38E29	FASTA	272	28,759
	10 20 30 40 50 60 MPNVNPAPIG VFDSGLGGLS VLREIRALLP HESLLYLADS KYAPYGEKPE AFVQARTLQA 70 80 90 100 110 120 CEWLLAQGCK ALVIACNTAT GHAVELLRQT LPVPIIGVEP GLKPAAAASQ SKVVGVLATA 130 140 150 160 170 180 NTLKSGKFAR LLASLDGESR FICEAGLGLV PLIEQGDIDG PDIRGRLDNY LTPMLEAGAD 190 200 210 220 230 240 TLVLGCTHYP FLSDTIRDMV GNQLTLVDTG SAIARQLARK LVEHDLAVAP GAVPQDRFVS 250 260 270 TKDAAHLRQM AAALLHIETQ AETVAIEPAP AF

References

[1]

"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000090 Genomic DNA. Translation: AAZ61596.1.
RefSeq	YP_296440.1. NC_007347.1.
3D structure databases
HSSP	HSSP built from PDB template 1ZUW based on UniProtKB P94556.
ProteinModelPortal	Q46Z37.
ModBase	Search...
Protein-protein interaction databases
STRING	Q46Z37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3610203.
GenomeReviews	Gene locus Reut_A2233 in contig CP000090_GR.
KEGG	reu:Reut_A2233.
NMPDR	fig|264198.3.peg.2836.
PATRIC	20230071. VBIRalEut24049_2881.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645102.
OMA	QCHVRLV.
ProtClustDB	PRK00865.
Enzyme and pathway databases
BioCyc	REUT264198:REUT_A2233-MONOMER.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_CUPPJ

Accession

Primary (citable) accession number: Q46Z37

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program