Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q46YY3 (FENR2_CUPPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase 2
Short name=FNR 2
Short name=Fd-NADP+ reductase 2
EC=1.18.1.2
Gene names
Ordered Locus Names:Reut_A2287
OrganismCupriavidus pinatubonensis (strain JMP134 / LMG 1197) (Alcaligenes eutrophus) (Ralstonia eutropha) [Complete proteome] [HAMAP]
Taxonomic identifier264198 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length368 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP MF_01685

Subunit structure

Homodimer By similarity. HAMAP MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular functionferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: EC

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 368368Ferredoxin--NADP reductase 2 HAMAP MF_01685
PRO_0000364906

Sites

Binding site571FAD By similarity
Binding site651FAD By similarity
Binding site701FAD By similarity
Binding site1101FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1451FAD; via amide nitrogen By similarity
Binding site3101FAD By similarity
Binding site3511FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
Q46YY3 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 7B6B4479A59DF36C

FASTA36840,013
        10         20         30         40         50         60 
MDLSIPNPVA DTTKAADAGT AGGQPLEIDA LIVGAGPVGL FQVFELGLLE IKAHVIDSLK 

        70         80         90        100        110        120 
VVGGQCVELY PDKPIYDIPA VPSCTGQELT DNLLKQIEPF GPTFHLGQEV AVVERRDDGR 

       130        140        150        160        170        180 
FFVETSLGTR FITKTIFIAA GVGSFQPRTL KVDGIDKFDG KQLFYRVKDP SRFHGRNLVI 

       190        200        210        220        230        240 
VGGGDSALDW TLDLVGKAES VVMIHRRDGF RAAPASVAKM KELCEQMEMQ FLVGQIGGYE 

       250        260        270        280        290        300 
EKDGVLTEIK VTGADGVTRR LPVDDVLVFF GLSPKLGPIA EWGLDLERKQ IKVDTEKFQT 

       310        320        330        340        350        360 
NIPGIFAVGD INTYPGKKKL ILSGFHEAAL AAFGAAPYIF PEKKIHMQYT TTSPKLHKVL 


GVESPVFD

« Hide

References

[1]"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000090 Genomic DNA. Translation: AAZ61650.1.
RefSeqYP_296494.1. NC_007347.1.

3D structure databases

ProteinModelPortalQ46YY3.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ46YY3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3611637.
GenomeReviewsGene locus Reut_A2287 in contig CP000090_GR.
KEGGreu:Reut_A2287.
NMPDRfig|264198.3.peg.3018.
PATRIC20230195. VBIRalEut24049_2939.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG669726.
OMAFQVFELG.
ProtClustDBCLSK939521.

Enzyme and pathway databases

BioCycREUT264198:REUT_A2287-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
[Tree]
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
KOK00384.
PANTHERPTHR22912:SF53. PTHR22912:SF53. 1 hit.
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR2_CUPPJ
AccessionPrimary (citable) accession number: Q46YY3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: September 13, 2005
Last modified: January 25, 2012
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents