ID   SDHD_RALEJ              Reviewed;         443 AA.
AC   Q46X58;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   16-JUN-2009, entry version 23.
DE   RecName: Full=Probable D-serine dehydratase;
DE            EC=4.3.1.18;
DE   AltName: Full=D-serine deaminase;
DE            Short=DSD;
GN   Name=dsdA; OrderedLocusNames=Reut_A2915;
OS   Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M.,
RA   Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Ralstonia eutropha JMP134.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-serine = pyruvate + NH(3).
CC   -!- COFACTOR: Pyridoxal phosphate (By similarity).
CC   -!- SIMILARITY: Belongs to the serine/threonine dehydratase family.
CC       DsdA subfamily.
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DR   EMBL; CP000090; AAZ62275.1; -; Genomic_DNA.
DR   RefSeq; YP_297119.1; -.
DR   GeneID; 3610457; -.
DR   GenomeReviews; CP000090_GR; Reut_A2915.
DR   KEGG; reu:Reut_A2915; -.
DR   NMPDR; fig|264198.3.peg.2697; -.
DR   HOGENOM; Q46X58; -.
DR   OMA; Q46X58; DHPLFVY.
DR   BioCyc; REUT264198:REUT_A2915-MON; -.
DR   GO; GO:0008721; F:D-serine ammonia-lyase activity; IEA:EC.
DR   GO; GO:0016836; F:hydro-lyase activity; IEA:HAMAP.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0046416; P:D-amino acid metabolic process; IEA:HAMAP.
DR   HAMAP; MF_01030; -; 1.
DR   InterPro; IPR011780; D_Ser_am_lyase.
DR   InterPro; IPR001926; PyrdxlP-dep_enz_bsu.
DR   InterPro; IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
DR   PANTHER; PTHR10314:SF9; D_Ser_am_lyase; 1.
DR   Pfam; PF00291; PALP; 1.
DR   TIGRFAMs; TIGR02035; D_Ser_am_lyase; 1.
DR   PROSITE; PS00165; DEHYDRATASE_SER_THR; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Lyase; Pyridoxal phosphate.
FT   CHAIN         1    443       Probable D-serine dehydratase.
FT                                /FTId=PRO_0000291738.
FT   MOD_RES     106    106       N6-(pyridoxal phosphate)lysine (By
FT                                similarity).
SQ   SEQUENCE   443 AA;  46704 MW;  5168A7877E95A088 CRC64;
     MVTLSLTPEL LAKLQSRQPL LWVNPRLGQP LPASAPSLEL IAAAEARLAR CAPLMAALFP
     ELASSHGQVE SQLMPATGLQ YALGEGAEGA WFIKRDDQLP TAGSIKARGG FHEVLAIAES
     IAIEHGMLDP DGDRRVLATE AARKLFSQYS VTVGSTGNLG LSIGVMAAAL GFDAVVHMSA
     DAKAWKKDRL RKRGVRVVEH EGDYAQAVAA GREQALGATR CHFVDDERSA LLFFGYAAAA
     RHLARQLAEA GRVVDAAHPL FVYLPCGVGG APGGITYGLK ALLGDHVHCF FAEPVASPCV
     LVQLASGSDD PVSVYDIGLD NRTDADGLAV GQASHLVSPL MASQLAGVFT VPDDQLYVQL
     LALKTSMGVE VEPSAAAGIG GPGWLRDSPE GRAYVRDHGL DMRDATHVIW ATGGSLVPRE
     ELHRFQAYAT ALAHVPGAMH KAA
//