Reviewed, UniProtKB/Swiss-Prot Q46VT8 (PHS2_RALEJ)

Names and origin

Protein names

Recommended name:
    Putative pterin-4-alpha-carbinolamine dehydratase 2
      Short name=PHS 2
    EC=4.2.1.96
Alternative name(s):
    4-alpha-hydroxy-tetrahydropterin dehydratase 2
    Pterin carbinolamine dehydratase 2
      Short name=PCD 2

Gene names

Ordered Locus Names:

Reut_A3388

Organism

Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) [Complete proteome] [HAMAP]

Taxonomic identifier

264198 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Cupriavidus

Protein attributes

Sequence length	100 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H2O. HAMAP MF_00434
Sequence similarities	Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

Ontologies

Keywords
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tetrahydrobiopterin biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	4-alpha-hydroxytetrahydrobiopterin dehydratase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 100	100	Putative pterin-4-alpha-carbinolamine dehydratase 2 HAMAP MF_00434		PRO_0000231470

Sequences

	Sequence		Length	Mass (Da)
	Q46VT8-1 [UniParc]. Last modified April 4, 2006. Version 2. Checksum: 5E750A0AC9613CFC	FASTA	100	11,368
	10 20 30 40 50 60 MTPLSPQARA TLLAELPGWT DVDNRDAIQK RFTFPDFNAA FAFMTRVAIQ AEKADHHPEW 70 80 90 100 FNVYNRVDIT LSTHDANGLT QRDIDLAHFI ERAAASLRVE

References

[1]

"Complete sequence of chromosome 1 of Ralstonia eutropha JMP134." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000090 Genomic DNA. Translation: AAZ62746.1. Different initiation.
RefSeq	YP_297590.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3610576.
GenomeReviews	Gene locus Reut_A3388 in contig CP000090_GR.
KEGG	reu:Reut_A3388.
NMPDR	fig|264198.3.peg.3875.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q46VT8.
Enzyme and pathway databases
BioCyc	REUT264198:REUT_A3388-MON.
Family and domain databases
HAMAP	MF_00434. [Tree]
InterPro	IPR001533. Trans/pterin_deHydtase. [Graphical view]
Gene3D	G3DSA:3.30.1360.20. Trans_pterinDh. 1 hit.
PANTHER	PTHR12599. Trans_pterinDh. 1 hit.
Pfam	PF01329. Pterin_4a. 1 hit. [Graphical view]
ProDom	PD007262. Trans_pterinDh. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

PHS2_RALEJ

Accession

Primary (citable) accession number: Q46VT8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	April 4, 2006
Last modified:	March 3, 2009
This is version 20 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)