ID   Q46V23_CUPPJ            Unreviewed;       539 AA.
AC   Q46V23;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   27-MAR-2024, entry version 95.
DE   SubName: Full=Histidine kinase, HAMP region:Bacterial chemotaxis sensory transducer {ECO:0000313|EMBL:AAZ63011.1};
GN   OrderedLocusNames=Reut_B3653 {ECO:0000313|EMBL:AAZ63011.1};
OS   Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Cupriavidus necator
OS   (strain JMP 134)).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=264198 {ECO:0000313|EMBL:AAZ63011.1};
RN   [1] {ECO:0000313|EMBL:AAZ63011.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JMP134 {ECO:0000313|EMBL:AAZ63011.1};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J.,
RA   Larimer F., Land M., Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 2 of Ralstonia eutropha JMP134.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000256|ARBA:ARBA00029447}.
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DR   EMBL; CP000091; AAZ63011.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q46V23; -.
DR   STRING; 264198.Reut_B3653; -.
DR   KEGG; reu:Reut_B3653; -.
DR   eggNOG; COG0840; Bacteria.
DR   HOGENOM; CLU_000445_107_27_4; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd06225; HAMP; 1.
DR   Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR024478; HlyB_4HB_MCP.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR   PANTHER; PTHR32089:SF119; METHYL-ACCEPTING CHEMOTAXIS PROTEIN TLPQ; 1.
DR   Pfam; PF12729; 4HB_MCP_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00283; MA; 1.
DR   SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Kinase {ECO:0000313|EMBL:AAZ63011.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW   ProRule:PRU00284}; Transferase {ECO:0000313|EMBL:AAZ63011.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        188..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          210..262
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          267..503
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000259|PROSITE:PS50111"
FT   COILED          79..106
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   539 AA;  58123 MW;  564107E3F40B7969 CRC64;
     MNHWTIRTRI LASFTFILLV MALMGVVAYN RLSAIERETN LMLKDALPGL NYSTGIRGAW
     GEVYVLAWET VKAGTESQRQ GYQQQSAEVR QRLDRLEQQY ESTITRDNDR ATFNQYKAAR
     SRYDQLALPL TQSASWKGGE AAEALLRGEA NQHWAEVRRL AQTLVDDNNA VNEKAAHGIN
     AAVSSAKIGI EVALLVAVAM SAICGYLLLR AITVPMRSIV GLLAGIRGGD LRLRMALGRG
     DEFQDVEQGF NQMTGELTSL VGQAQRSAIQ VTTSVNEIAA TARQQQATAT ETAATTTQIG
     ATSREISATA RDLVRTINEV SNAAEQTAGL AGTGQVGLSR MEATMQHVMD AAGSVNAKLA
     TLNEKAGNIN QVVTTIAKVA DQTNLLSLNA AIEAEKAGEY GRGFSVVATE IRRLADQTAV
     ATYDIEQMVR EIQSAVAAGV MGMDKFSEEV RRGMSDVTQV GDQLSQIIGQ VQSLAPRVLM
     VNEGMQAQAG GAEQINQALM QLSEAAQQTV ESLRQSSQAI DELTLVANEL RSGVSRFKV
//