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Q46S32 (TYPH2_CUPPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase 2

EC=2.4.2.4
Alternative name(s):
TdRPase 2
Gene names
Ordered Locus Names:Reut_B4704
OrganismCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134)) [Complete proteome] [HAMAP]
Taxonomic identifier264198 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

Protein attributes

Sequence length512 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 512512Putative thymidine phosphorylase 2 HAMAP-Rule MF_00703
PRO_0000314711

Sequences

Sequence LengthMass (Da)Tools
Q46S32 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 8CCDB5A89B7907E7

FASTA51253,921
        10         20         30         40         50         60 
MQANELKLAA GEGQGSEPLI FKPLGIDTWQ EHVIYLHPDC PVCRAEGFTA QARVQVRIGE 

        70         80         90        100        110        120 
ASLIATLNLV GAPLLDTGEA SLSASAAQAL EARAGDVVAI SHAPALESVR ALRAKIYGRR 

       130        140        150        160        170        180 
LDGAQIDSII SDISAGRYPD VYISAFLAAC ADGRMNRRET VDLTRAMVHS GERLSWSHAV 

       190        200        210        220        230        240 
VADKHCVGGL PGNRTTPIVV AIAAAGGLVL PKTSSRAITS PAGTADTMET LTRVALSAAE 

       250        260        270        280        290        300 
LRHVVERVGA SLVWGGALNL SPADDILIRV ERALDIDSDA QLVASILSKK VAAGSTHILI 

       310        320        330        340        350        360 
DVPVGPTAKV REDRDLERLE AAMRHVAGAF GLHILMVRTD GTQPLGRGIG PALEARDILA 

       370        380        390        400        410        420 
VLQRTVAAPP DLRERSVMLA GALLEFCGAA PRGAGEKAAG QLLDSGAAWR KFQAICEAQG 

       430        440        450        460        470        480 
GLRVPGEAIF RRDIVAPHAG KVIAIDNRHI ARTAKLAGAP MRQVAGLEMR VRVNDEVRAG 

       490        500        510 
QPLFTVHAQA SGELDYSCSY ALAHPAVSIE PH 

« Hide

References

[1]"Complete sequence of chromosome 2 of Ralstonia eutropha JMP134."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000091 Genomic DNA. Translation: AAZ64052.1.
RefSeqYP_298896.1. NC_007348.1.

3D structure databases

ProteinModelPortalQ46S32.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264198.Reut_B4704.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ64052; AAZ64052; Reut_B4704.
GeneID3613942.
KEGGreu:Reut_B4704.
PATRIC20235285. VBIRalEut24049_5444.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OMARVECAIT.
OrthoDBEOG61ZTGG.

Enzyme and pathway databases

BioCycCPIN264198:GIW3-4780-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH2_CUPPJ
AccessionPrimary (citable) accession number: Q46S32
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families