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Protein

Putative thymidine phosphorylase 2

Gene

Reut_B4704

Organism
Cupriavidus necator (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative thymidine phosphorylase 2UniRule annotation (EC:2.4.2.4UniRule annotation)
Alternative name(s):
TdRPase 2UniRule annotation
Gene namesi
Ordered Locus Names:Reut_B4704
OrganismiCupriavidus necator (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000002697 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003147111 – 512Putative thymidine phosphorylase 2Add BLAST512

Proteomic databases

PRIDEiQ46S32

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_B4704

Structurei

3D structure databases

ProteinModelPortaliQ46S32
SMRiQ46S32
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CMW Bacteria
COG0213 LUCA
HOGENOMiHOG000252767
KOiK00758
OMAiANEIYEC
OrthoDBiPOG091H02BC

Family and domain databases

Gene3Di3.40.1030.10, 2 hits
3.90.1170.30, 1 hit
HAMAPiMF_00703 Thymid_phosp_2, 1 hit
InterProiView protein in InterPro
IPR000312 Glycosyl_Trfase_fam3
IPR017459 Glycosyl_Trfase_fam3_N_dom
IPR036320 Glycosyl_Trfase_fam3_N_dom)sf
IPR035902 Nuc_phospho_transferase
IPR036566 PYNP-like_C_sf
IPR013102 PYNP_C
IPR017872 Pyrmidine_PPase_CS
IPR028579 Thym_Pase_Put
IPR013466 Thymidine/AMP_Pase
IPR000053 Thymidine/pyrmidine_PPase
PANTHERiPTHR10515 PTHR10515, 1 hit
PfamiView protein in Pfam
PF02885 Glycos_trans_3N, 1 hit
PF00591 Glycos_transf_3, 1 hit
PF07831 PYNP_C, 1 hit
PIRSFiPIRSF000478 TP_PyNP, 1 hit
SMARTiView protein in SMART
SM00941 PYNP_C, 1 hit
SUPFAMiSSF47648 SSF47648, 1 hit
SSF52418 SSF52418, 1 hit
SSF54680 SSF54680, 1 hit
TIGRFAMsiTIGR02645 ARCH_P_rylase, 1 hit
PROSITEiView protein in PROSITE
PS00647 THYMID_PHOSPHORYLASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q46S32-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQANELKLAA GEGQGSEPLI FKPLGIDTWQ EHVIYLHPDC PVCRAEGFTA
60 70 80 90 100
QARVQVRIGE ASLIATLNLV GAPLLDTGEA SLSASAAQAL EARAGDVVAI
110 120 130 140 150
SHAPALESVR ALRAKIYGRR LDGAQIDSII SDISAGRYPD VYISAFLAAC
160 170 180 190 200
ADGRMNRRET VDLTRAMVHS GERLSWSHAV VADKHCVGGL PGNRTTPIVV
210 220 230 240 250
AIAAAGGLVL PKTSSRAITS PAGTADTMET LTRVALSAAE LRHVVERVGA
260 270 280 290 300
SLVWGGALNL SPADDILIRV ERALDIDSDA QLVASILSKK VAAGSTHILI
310 320 330 340 350
DVPVGPTAKV REDRDLERLE AAMRHVAGAF GLHILMVRTD GTQPLGRGIG
360 370 380 390 400
PALEARDILA VLQRTVAAPP DLRERSVMLA GALLEFCGAA PRGAGEKAAG
410 420 430 440 450
QLLDSGAAWR KFQAICEAQG GLRVPGEAIF RRDIVAPHAG KVIAIDNRHI
460 470 480 490 500
ARTAKLAGAP MRQVAGLEMR VRVNDEVRAG QPLFTVHAQA SGELDYSCSY
510
ALAHPAVSIE PH
Length:512
Mass (Da):53,921
Last modified:September 13, 2005 - v1
Checksum:i8CCDB5A89B7907E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000091 Genomic DNA Translation: AAZ64052.1
RefSeqiWP_011300818.1, NC_007348.1

Genome annotation databases

EnsemblBacteriaiAAZ64052; AAZ64052; Reut_B4704
KEGGireu:Reut_B4704

Similar proteinsi

Entry informationi

Entry nameiTYPH2_CUPNJ
AccessioniPrimary (citable) accession number: Q46S32
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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