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Protein
Submitted name:

ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase module

Gene

Reut_B5079

Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-5156-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-dependent DNA ligase LigD phosphoesterase module / ATP-dependent DNA ligase LigD polymerase moduleImported
Gene namesi
Ordered Locus Names:Reut_B5079Imported
OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))Imported
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002697: Chromosome 2

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_B5079.

Structurei

3D structure databases

ProteinModelPortaliQ46R07.
SMRiQ46R07. Positions 605-890.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46R07-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKTTRQTPD DTRGTRSTRT AEPARKRPAD ALGKYRQMRD FAATPEPGGT
60 70 80 90 100
RQRARATPKA KRAGTLSFVI QKHAARRLHY DFRLELDGTL KSWAVPKGPS
110 120 130 140 150
LDPADKRMAV HVEDHPLDYA GFEGVIPPGH YGAGTVIVWD RGIWVPDGDA
160 170 180 190 200
DAAYRAGKLK FELRGEKLHG HWTLVRMHGS RQKEQDAWLL IKERDDAAVP
210 220 230 240 250
ASEFDVTEAL PDSVLAGTSA ARKTTGRRAA TNATKPGNGA KDSTKDSART
260 270 280 290 300
KPLPLPRRAT AAALPLALSP QLATLVERAP PDADAWRYEI KFDGYRMLAR
310 320 330 340 350
IDGDDVRLFT RQGHDWTSRL KTLAREVRAL GLPDGWLDGE IVVLGKHGET
360 370 380 390 400
DFQALQNAFE TSHVESIQYF VFDLPFYAGH DLRKAPLSER RALLRRLFEN
410 420 430 440 450
NTGTRLRFSE EFEAAPDEML DAACRMKLEG VIGKRIDAPY VSTRSNTWIK
460 470 480 490 500
LKCTQRQEFV IGGFTEPKGS RQGLGSLLLG VHDSAGRLRY AGNVGTGFDT
510 520 530 540 550
RSLASLREQL DAQRTDKAPF HELPSSIKGL WVRPRLVAEV SFGSWTREGR
560 570 580 590 600
VRHAVFHGLR SDKPASAVSV EKPAAPAGRK TAATTAARSA PATTRKGKPT
610 620 630 640 650
AANGKVAISH SERVIDTASG LTKGDLVRYY ESAAPLMLPH LRGRPIAMVR
660 670 680 690 700
APAGVAGQQF FQRHGDTLKI DGVNVLDPDL WPGHPALLEI VSEHALVAAA
710 720 730 740 750
QLNVVEFHTW NANKRSMDRP NRIIFDLDPG EGVPWPHMRE AAALMKAWLD
760 770 780 790 800
ELGLASFLKT SGGKGLHVVV PLTPRAGWDE VKEFAHGVVL HMAVTIPQRF
810 820 830 840 850
VAKSGAGNRI GKIFIDYLRN GVGATTAAAF SARARPGLGV SVPLAWDELD
860 870 880 890 900
GLEASDQWTV ANVAPRLDEL ARHDPWDTYA DTRQTITRAA TRLARAGRSK

P
Length:901
Mass (Da):98,871
Last modified:September 13, 2005 - v1
Checksum:i250BDFD8F1B2E563
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000091 Genomic DNA. Translation: AAZ64427.1.
RefSeqiYP_299271.1. NC_007348.1.

Genome annotation databases

EnsemblBacteriaiAAZ64427; AAZ64427; Reut_B5079.
GeneIDi3613364.
KEGGireu:Reut_B5079.
PATRICi20236083. VBIRalEut24049_5843.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000091 Genomic DNA. Translation: AAZ64427.1.
RefSeqiYP_299271.1. NC_007348.1.

3D structure databases

ProteinModelPortaliQ46R07.
SMRiQ46R07. Positions 605-890.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi264198.Reut_B5079.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ64427; AAZ64427; Reut_B5079.
GeneIDi3613364.
KEGGireu:Reut_B5079.
PATRICi20236083. VBIRalEut24049_5843.

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiHPLDYAD.
OrthoDBiEOG661H49.

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-5156-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome 2 of Ralstonia eutropha JMP134."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JMP134 / LMG 1197Imported.

Entry informationi

Entry nameiQ46R07_CUPPJ
AccessioniPrimary (citable) accession number: Q46R07
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: January 7, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.