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Q46QB2

- GLK_CUPPJ

UniProt

Q46QB2 - GLK_CUPPJ

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Protein
Glucokinase
Gene
glk, Reut_B5327
Organism
Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-glucose = ADP + D-glucose 6-phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 266ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. glucokinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPIN264198:GIW3-5404-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucokinase (EC:2.7.1.2)
Alternative name(s):
Glucose kinase
Gene namesi
Name:glk
Ordered Locus Names:Reut_B5327
OrganismiCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134))
Taxonomic identifieri264198 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
ProteomesiUP000002697: Chromosome 2

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 343343GlucokinaseUniRule annotation
PRO_0000268780Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi264198.Reut_B5327.

Structurei

3D structure databases

ProteinModelPortaliQ46QB2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0837.
HOGENOMiHOG000274469.
KOiK00845.
OMAiDWVEMTN.
OrthoDBiEOG64BQ47.

Family and domain databases

HAMAPiMF_00524. Glucokinase.
InterProiIPR003836. Glucokinase.
[Graphical view]
PfamiPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00749. glk. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46QB2-1 [UniParc]FASTAAdd to Basket

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MSNAMAASAV PDDTAYPRLL ADVGGTNVRF ALETAPMQIG AVTALKVADH    50
PSLEAAMRHY RDALSASGAK LPRHAAIGLA NPVTGDHVRL TNHDWAFSIE 100
ATRQALGLQT LVAINDFTSL ALGLPYLGAN DLVQIRSGQA VATAPRALIG 150
PGTGLGVSGL VPAPGGGAVA LAGEGGHIEL MPVTDDEWIA WRATHASLGR 200
VSAERLLSGM GLSQIHAALS AETGTRVDVP LTPEQVTTGA FARHDPLCER 250
TMAVFFGLLG SVAADIALVM GALGGVYLGG GILPRFVPAL QASAFNARFV 300
AKGRMRGYLD KLPVYVITAS YPALPGLARA LADTLSHGRP HIG 343
Length:343
Mass (Da):35,393
Last modified:September 13, 2005 - v1
Checksum:iDDC0B2E1ACE82FA7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000091 Genomic DNA. Translation: AAZ64672.1.
RefSeqiWP_011301436.1. NC_007348.1.
YP_299516.1. NC_007348.1.

Genome annotation databases

EnsemblBacteriaiAAZ64672; AAZ64672; Reut_B5327.
GeneIDi3612765.
KEGGireu:Reut_B5327.
PATRICi20236587. VBIRalEut24049_6095.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000091 Genomic DNA. Translation: AAZ64672.1 .
RefSeqi WP_011301436.1. NC_007348.1.
YP_299516.1. NC_007348.1.

3D structure databases

ProteinModelPortali Q46QB2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 264198.Reut_B5327.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ64672 ; AAZ64672 ; Reut_B5327 .
GeneIDi 3612765.
KEGGi reu:Reut_B5327.
PATRICi 20236587. VBIRalEut24049_6095.

Phylogenomic databases

eggNOGi COG0837.
HOGENOMi HOG000274469.
KOi K00845.
OMAi DWVEMTN.
OrthoDBi EOG64BQ47.

Enzyme and pathway databases

BioCyci CPIN264198:GIW3-5404-MONOMER.

Family and domain databases

HAMAPi MF_00524. Glucokinase.
InterProi IPR003836. Glucokinase.
[Graphical view ]
Pfami PF02685. Glucokinase. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00749. glk. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome 2 of Ralstonia eutropha JMP134."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JMP134 / LMG 1197.

Entry informationi

Entry nameiGLK_CUPPJ
AccessioniPrimary (citable) accession number: Q46QB2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: September 3, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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