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Q46QB2 (GLK_CUPPJ) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucokinase

EC=2.7.1.2
Alternative name(s):
Glucose kinase
Gene names
Name:glk
Ordered Locus Names:Reut_B5327
OrganismCupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstonia eutropha (strain JMP 134)) [Complete proteome] [HAMAP]
Taxonomic identifier264198 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus

Protein attributes

Sequence length343 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-glucose = ADP + D-glucose 6-phosphate. HAMAP-Rule MF_00524

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00524.

Sequence similarities

Belongs to the bacterial glucokinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glucokinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 343343Glucokinase HAMAP-Rule MF_00524
PRO_0000268780

Regions

Nucleotide binding21 – 266ATP Potential

Sequences

Sequence LengthMass (Da)Tools
Q46QB2 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: DDC0B2E1ACE82FA7

FASTA34335,393
        10         20         30         40         50         60 
MSNAMAASAV PDDTAYPRLL ADVGGTNVRF ALETAPMQIG AVTALKVADH PSLEAAMRHY 

        70         80         90        100        110        120 
RDALSASGAK LPRHAAIGLA NPVTGDHVRL TNHDWAFSIE ATRQALGLQT LVAINDFTSL 

       130        140        150        160        170        180 
ALGLPYLGAN DLVQIRSGQA VATAPRALIG PGTGLGVSGL VPAPGGGAVA LAGEGGHIEL 

       190        200        210        220        230        240 
MPVTDDEWIA WRATHASLGR VSAERLLSGM GLSQIHAALS AETGTRVDVP LTPEQVTTGA 

       250        260        270        280        290        300 
FARHDPLCER TMAVFFGLLG SVAADIALVM GALGGVYLGG GILPRFVPAL QASAFNARFV 

       310        320        330        340 
AKGRMRGYLD KLPVYVITAS YPALPGLARA LADTLSHGRP HIG 

« Hide

References

[1]"Complete sequence of chromosome 2 of Ralstonia eutropha JMP134."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Goltsman E., Martinez M., Schmutz J., Larimer F., Land M., Lykidis A., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: JMP134 / LMG 1197.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000091 Genomic DNA. Translation: AAZ64672.1.
RefSeqYP_299516.1. NC_007348.1.

3D structure databases

ProteinModelPortalQ46QB2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING264198.Reut_B5327.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ64672; AAZ64672; Reut_B5327.
GeneID3612765.
KEGGreu:Reut_B5327.
PATRIC20236587. VBIRalEut24049_6095.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0837.
HOGENOMHOG000274469.
KOK00845.
OMADWVEMTN.
OrthoDBEOG64BQ47.
ProtClustDBCLSK769004.

Enzyme and pathway databases

BioCycCPIN264198:GIW3-5404-MONOMER.

Family and domain databases

HAMAPMF_00524. Glucokinase.
InterProIPR003836. Glucokinase.
[Graphical view]
PfamPF02685. Glucokinase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00749. glk. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLK_CUPPJ
AccessionPrimary (citable) accession number: Q46QB2
Entry history
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: April 16, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families