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Protein

1,4-alpha-glucan branching enzyme GlgB

Gene

glgB

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.UniRule annotation

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei431NucleophileUniRule annotation1
Active sitei484Proton donorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase
Biological processCarbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Enzyme and pathway databases

BioCyciPMAR59920:G1G4T-610-MONOMER
UniPathwayiUPA00164

Protein family/group databases

CAZyiCBM48 Carbohydrate-Binding Module Family 48
GH13 Glycoside Hydrolase Family 13

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan branching enzyme GlgBUniRule annotation (EC:2.4.1.18UniRule annotation)
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferaseUniRule annotation
Alpha-(1->4)-glucan branching enzymeUniRule annotation
Glycogen branching enzymeUniRule annotation
Short name:
BEUniRule annotation
Gene namesi
Name:glgBUniRule annotation
Ordered Locus Names:PMN2A_0020
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002606751 – 7551,4-alpha-glucan branching enzyme GlgBAdd BLAST755

Proteomic databases

PRIDEiQ46LW6

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ46LW6
SMRiQ46LW6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000283037
KOiK00700
OMAiEVVHGKS
OrthoDBiPOG091H08D1
PhylomeDBiQ46LW6

Family and domain databases

Gene3Di2.60.40.10, 1 hit
2.60.40.1180, 1 hit
HAMAPiMF_00685 GlgB, 1 hit
InterProiView protein in InterPro
IPR006048 A-amylase/branching_C
IPR037439 Branching_enzy
IPR006407 GlgB
IPR006047 Glyco_hydro_13_cat_dom
IPR004193 Glyco_hydro_13_N
IPR013780 Glyco_hydro_b
IPR017853 Glycoside_hydrolase_SF
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
PANTHERiPTHR43651 PTHR43651, 2 hits
PfamiView protein in Pfam
PF00128 Alpha-amylase, 1 hit
PF02806 Alpha-amylase_C, 1 hit
PF02922 CBM_48, 1 hit
PIRSFiPIRSF000463 GlgB, 1 hit
SMARTiView protein in SMART
SM00642 Aamy, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
SSF81296 SSF81296, 2 hits
TIGRFAMsiTIGR01515 branching_enzym, 1 hit

Sequencei

Sequence statusi: Complete.

Q46LW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVSILLDSL KDDGQRLSEC RHESPFSILG PQPFKDKWII RIWMPEASQV
60 70 80 90 100
ELVTQQTKIK LQNPNHEWIF EGVLEKDPGT DYQIKVNRGG IEHVQHDPWS
110 120 130 140 150
FRKEWMGEID RHLFAEGNHH HIWRKMGAHL TEIDKKKGVM FCLWAPHAKS
160 170 180 190 200
VSVIGDLNSW DGRHHPMQKR LGGIWELFIP GLSEGDLYKY EIRTEKGHCY
210 220 230 240 250
EKADPYGFQH EVRPAKSSVI SKIDSFQWSD QSWISNRDNR DPLEQPISVY
260 270 280 290 300
EMHLGSWMHA SSDDPFINSN GEHRAPVPAA DMKPGSRLLT YKELANKVIP
310 320 330 340 350
YVKERGFTHI ELMPISEHPF DGSWGYQVTG WYAPTSRFGS PDEFRAFVDS
360 370 380 390 400
CHKEGIGIIL DWVPGHFPKD QHGLAYFDGS HLYEHSDPRV GEHKEWGTLI
410 420 430 440 450
FNYSRNEVRN FLVANLIFWF DQFHIDGIRV DAVASMLYKD YLRPEGEWIP
460 470 480 490 500
NEDGGNENFE AVRFLQQANH VLFQHFPGAL SIAEESTTWT GVTKPTDMDG
510 520 530 540 550
LGFNLKWNMG WMHDMLDYFE IDPWFRQFNQ NNITFSICYN FTENFMLALS
560 570 580 590 600
HDEVVHGKSH LLHKMPGDDW QKYANTRALL AYMWTHPGKK TIFMGMEFGQ
610 620 630 640 650
RQEWNVWDDL QWDLLNYEPH KGIQKLVDDL NNLYKREPAL WRNDFDEYGF
660 670 680 690 700
QWIDCDDNKN SVISFMRREK TDGEWLVIVA NFTPQNHSNY RIGVPVDGFY
710 720 730 740 750
EEIFNTDASQ YGGSNLGNMG GKSTDLYNIH GYENSIDLCL PPLSVLVLKH

KSKKN
Length:755
Mass (Da):87,913
Last modified:September 13, 2005 - v1
Checksum:i59B52C5C92E11B8F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA Translation: AAZ57512.1
RefSeqiWP_011293554.1, NC_007335.2

Genome annotation databases

EnsemblBacteriaiAAZ57512; AAZ57512; PMN2A_0020
KEGGipmn:PMN2A_0020

Similar proteinsi

Entry informationi

Entry nameiGLGB_PROMT
AccessioniPrimary (citable) accession number: Q46LW6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 13, 2005
Last modified: May 23, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

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