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Q46LW6 (GLGB_PROMT) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
1,4-alpha-glucan branching enzyme GlgB

EC=2.4.1.18
Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE
Gene names
Name:glgB
Ordered Locus Names:PMN2A_0020
OrganismProchlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP]
Taxonomic identifier59920 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus

Protein attributes

Sequence length755 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP-Rule MF_00685

Catalytic activity

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP-Rule MF_00685

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00685

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00685

Sequence similarities

Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7557551,4-alpha-glucan branching enzyme GlgB HAMAP-Rule MF_00685
PRO_0000260675

Sites

Active site4311Nucleophile By similarity
Active site4841Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q46LW6 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 59B52C5C92E11B8F

FASTA75587,913
        10         20         30         40         50         60 
MTVSILLDSL KDDGQRLSEC RHESPFSILG PQPFKDKWII RIWMPEASQV ELVTQQTKIK 

        70         80         90        100        110        120 
LQNPNHEWIF EGVLEKDPGT DYQIKVNRGG IEHVQHDPWS FRKEWMGEID RHLFAEGNHH 

       130        140        150        160        170        180 
HIWRKMGAHL TEIDKKKGVM FCLWAPHAKS VSVIGDLNSW DGRHHPMQKR LGGIWELFIP 

       190        200        210        220        230        240 
GLSEGDLYKY EIRTEKGHCY EKADPYGFQH EVRPAKSSVI SKIDSFQWSD QSWISNRDNR 

       250        260        270        280        290        300 
DPLEQPISVY EMHLGSWMHA SSDDPFINSN GEHRAPVPAA DMKPGSRLLT YKELANKVIP 

       310        320        330        340        350        360 
YVKERGFTHI ELMPISEHPF DGSWGYQVTG WYAPTSRFGS PDEFRAFVDS CHKEGIGIIL 

       370        380        390        400        410        420 
DWVPGHFPKD QHGLAYFDGS HLYEHSDPRV GEHKEWGTLI FNYSRNEVRN FLVANLIFWF 

       430        440        450        460        470        480 
DQFHIDGIRV DAVASMLYKD YLRPEGEWIP NEDGGNENFE AVRFLQQANH VLFQHFPGAL 

       490        500        510        520        530        540 
SIAEESTTWT GVTKPTDMDG LGFNLKWNMG WMHDMLDYFE IDPWFRQFNQ NNITFSICYN 

       550        560        570        580        590        600 
FTENFMLALS HDEVVHGKSH LLHKMPGDDW QKYANTRALL AYMWTHPGKK TIFMGMEFGQ 

       610        620        630        640        650        660 
RQEWNVWDDL QWDLLNYEPH KGIQKLVDDL NNLYKREPAL WRNDFDEYGF QWIDCDDNKN 

       670        680        690        700        710        720 
SVISFMRREK TDGEWLVIVA NFTPQNHSNY RIGVPVDGFY EEIFNTDASQ YGGSNLGNMG 

       730        740        750 
GKSTDLYNIH GYENSIDLCL PPLSVLVLKH KSKKN 

« Hide

References

[1]"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus."
Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W.
PLoS Genet. 3:2515-2528(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NATL2A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000095 Genomic DNA. Translation: AAZ57512.1.
RefSeqYP_291215.1. NC_007335.2.

3D structure databases

ProteinModelPortalQ46LW6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING59920.PMN2A_0020.

Protein family/group databases

CAZyCBM48. Carbohydrate-Binding Module Family 48.
GH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ57512; AAZ57512; PMN2A_0020.
GeneID3605384.
KEGGpmn:PMN2A_0020.
PATRIC23023377. VBIProMar14922_0632.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0296.
HOGENOMHOG000283037.
KOK00700.
OMAISEGRHE.
OrthoDBEOG6JX7GT.
PhylomeDBQ46LW6.

Enzyme and pathway databases

BioCycPMAR59920:GI1O-646-MONOMER.
UniPathwayUPA00164.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
HAMAPMF_00685. GlgB.
InterProIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERPTHR10357. PTHR10357. 1 hit.
PfamPF00128. Alpha-amylase. 2 hits.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFPIRSF000463. GlgB. 1 hit.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF81296. SSF81296. 2 hits.
TIGRFAMsTIGR01515. branching_enzym. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGB_PROMT
AccessionPrimary (citable) accession number: Q46LW6
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: September 13, 2005
Last modified: July 9, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries