Reviewed, UniProtKB/Swiss-Prot Q46LT5 (COMB_PROMT)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	PMN2A_0051

Organism

Prochlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP]

Taxonomic identifier

59920 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 242	242	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000014468

Sequences

	Sequence		Length	Mass (Da)
	Q46LT5-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: BDC9B81CE4D35FFF	FASTA	242	26,333
	10 20 30 40 50 60 MKLSYFYVAA DVPDGIIPES SVVIDVLRAT TTIAWALENG ADSVQVFADV DELKNQAKTF 70 80 90 100 110 120 DSKEKILVGE RGGKKLDGFD LGNSPLGVSP ESVKGKRVFM STTNGTRSLH RVRESKSLYT 130 140 150 160 170 180 MALPNRKAIA ERLKSDNPKE VWIVGSGWEG SYSLEDSLAA GALASLLMDQ LESVQIVNDE 190 200 210 220 230 240 LMASVALWKN WENDVEGCLR IASHGQRLAG IGNHDDDFAC CASLDNLSVI PKQIEMGVLR SN

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000095 Genomic DNA. Translation: AAZ57543.1.
RefSeq	YP_291246.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3605420.
GenomeReviews	Gene locus PMN2A_0051 in contig CP000095_GR.
KEGG	pmn:PMN2A_0051.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q46LT5.
OMA	Q46LT5. ATTTIAW.
Enzyme and pathway databases
BioCyc	PMAR59920:PMN2A_0051-MON.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
TIGRFAMs	TIGR00298. 2-ph_phosphatase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_PROMT

Accession

Primary (citable) accession number: Q46LT5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	May 5, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)