Reviewed, UniProtKB/Swiss-Prot Q46LG3 (FBSB_PROMT)

Names and origin

Protein names

Recommended name:
    D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
      Short name=FBPase class 2/SBPase
    EC=3.1.3.11
    EC=3.1.3.37

Gene names

Ordered Locus Names:

PMN2A_0173

Organism

Prochlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP]

Taxonomic identifier

59920 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	334 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. Sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the FBPase class 2 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: InterPro reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC sedoheptulose-bisphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 334	334	D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase		PRO_0000342722

Sequences

	Sequence		Length	Mass (Da)
	Q46LG3-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 842641A9E8C46EFF	FASTA	334	35,271
	10 20 30 40 50 60 MDRTLVQEIL EVVEQAAIAS AQLTGLGQKD EADAAAVEAM RKRMGTIQMQ GRIVIGEGER 70 80 90 100 110 120 DEAPMLYIGE EVGSGTGPGV DFAVDPCEGT NLCANSQRGS MAVLAASDRG GLFNAPDFYM 130 140 150 160 170 180 NKLAAPPAAK GKVDIRKTPT ENIKILSDCL GIAISDLTIV VMDRARHKNL VSEIRSTGAR 190 200 210 220 230 240 IQPISDGDVQ AAIACGFEGT GTHCLMGIGA APEGVISAAA MRALGGHFQG QLVYDPAIAQ 250 260 270 280 290 300 TSEWADYTKE GNIKRLNEMG ITDIDKIYEA NELASGENVA FAGSGITDGL LFDGVKFEKD 310 320 330 CTRTSSLVIS TLDQTARFTN TVHIKDGAQS ISLK

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000095 Genomic DNA. Translation: AAZ57665.1.
RefSeq	YP_291368.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3605543.
GenomeReviews	Gene locus PMN2A_0173 in contig CP000095_GR.
KEGG	pmn:PMN2A_0173.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	Q46LG3. TSEWADM.
Enzyme and pathway databases
BioCyc	PMAR59920:PMN2A_0173-MON.
Family and domain databases
InterPro	IPR004464. GlpX. [Graphical view]
Pfam	PF03320. FBPase_glpX. 1 hit. [Graphical view]
PIRSF	PIRSF004532. GlpX. 1 hit.
ProDom	PD007014. GlpX. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00330. glpX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FBSB_PROMT

Accession

Primary (citable) accession number: Q46LG3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)