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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei322 – 3221Proton donorUniRule annotation
Active sitei351 – 3511UniRule annotation
Active sitei453 – 4531UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-970-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PMN2A_0320
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 524524Glucose-6-phosphate isomerasePRO_0000230926Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59920.PMN2A_0320.

Structurei

3D structure databases

ProteinModelPortaliQ46L16.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.
PhylomeDBiQ46L16.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46L16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNNDKWARY CDLLYSDDSL GFWLDISRMD VAINDFEDFN EIYSKAFDAL
60 70 80 90 100
ESLENGSIAN IDEGRQVGHY WLRNPKVAPS PEISDSITKE IQDISKFGSS
110 120 130 140 150
ILNGEITNSD GEKYTDVFWI GIGGSGLGPL LIKESFKRES IGLDLHFLDN
160 170 180 190 200
VDPEGISHKL NSILPNLNST LFVVVSKSGG TPEPLIGMEQ AMKFVRDNNQ
210 220 230 240 250
NWSSRAIAIT SKGSKLDLLA HNENWLDIFD LPDWVGGRTS ITGAVGLLPA
260 270 280 290 300
ALIGADINKF LNGASQMDAL TRVKDIKNNP AALLSLAWFK SGNGKGLRDM
310 320 330 340 350
VVLPYRDRLE VFSRYLQQLV MESLGKKFDR DENQVNQGIA VYGNKGSTDQ
360 370 380 390 400
HAYVQQLRDG IDNFFVNFIE ILHDPLEIVE VKNKRPGDYL SGFLQGTRSA
410 420 430 440 450
LTEGGRQNLT ITFKSFDESS LGALIALFER AVSLYAELIN VNAYNQPGVE
460 470 480 490 500
AGKKAATKII KLQKEIEELL DDGKQRTLNE INDALSSDST ESIYLILRKL
510 520
SENSDHYSMI GNQSNPDKLI ISKT
Length:524
Mass (Da):58,233
Last modified:April 4, 2006 - v2
Checksum:iEA6E01B3F90E16D7
GO

Sequence cautioni

The sequence AAZ57812.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA. Translation: AAZ57812.1. Different initiation.
RefSeqiYP_291515.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ57812; AAZ57812; PMN2A_0320.
KEGGipmn:PMN2A_0320.
PATRICi23024027. VBIProMar14922_0953.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA. Translation: AAZ57812.1. Different initiation.
RefSeqiYP_291515.1. NC_007335.2.

3D structure databases

ProteinModelPortaliQ46L16.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi59920.PMN2A_0320.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ57812; AAZ57812; PMN2A_0320.
KEGGipmn:PMN2A_0320.
PATRICi23024027. VBIProMar14922_0953.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.
PhylomeDBiQ46L16.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciPMAR59920:GI1O-970-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2A.

Entry informationi

Entry nameiG6PI_PROMT
AccessioniPrimary (citable) accession number: Q46L16
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: May 27, 2015
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.