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Q46JN4

- RNPA_PROMT

UniProt

Q46JN4 - RNPA_PROMT

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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-1642-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:PMN2A_0803
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 128128Ribonuclease P protein componentPRO_1000194664Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi59920.PMN2A_0803.

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000266301.
KOiK03536.
OMAiMRLKGHR.
OrthoDBiEOG6N94CP.
PhylomeDBiQ46JN4.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46JN4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVLPKHMRLK GHRCFDFIYK EGSRFYSSSM VLRVTDANKK PQVKGKQSKT
60 70 80 90 100
RHSIKCAISI SNKVSKKSVT RNKLRRLFHH HLSLRLSNMA CDNEIWAFIS
110 120
LKPSCMKNPD STLLKECDKL LTKAGITK
Length:128
Mass (Da):14,748
Last modified:September 13, 2005 - v1
Checksum:i4A9E57A7E7A8E861
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA. Translation: AAZ58294.1.
RefSeqiYP_291997.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ58294; AAZ58294; PMN2A_0803.
GeneIDi3606182.
KEGGipmn:PMN2A_0803.
PATRICi23025371. VBIProMar14922_1619.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA. Translation: AAZ58294.1 .
RefSeqi YP_291997.1. NC_007335.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59920.PMN2A_0803.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ58294 ; AAZ58294 ; PMN2A_0803 .
GeneIDi 3606182.
KEGGi pmn:PMN2A_0803.
PATRICi 23025371. VBIProMar14922_1619.

Phylogenomic databases

HOGENOMi HOG000266301.
KOi K03536.
OMAi MRLKGHR.
OrthoDBi EOG6N94CP.
PhylomeDBi Q46JN4.

Enzyme and pathway databases

BioCyci PMAR59920:GI1O-1642-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2A.

Entry informationi

Entry nameiRNPA_PROMT
AccessioniPrimary (citable) accession number: Q46JN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3