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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei146GTPUniRule annotation1
Binding sitei150GTPUniRule annotation1
Binding sitei193GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi28 – 32GTPUniRule annotation5
Nucleotide bindingi115 – 117GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:PMN2A_0875Imported
OrganismiProchlorococcus marinus (strain NATL2A)Imported
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002535 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ46JG2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 211TubulinInterPro annotationAdd BLAST192
Domaini213 – 331Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
OrthoDBiPOG091H02KK
PhylomeDBiQ46JG2

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.30.1330.20, 1 hit
3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR037103 Tubulin/FtsZ_C_sf
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q46JG2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNKSSFNMD EGILPSQSAR IEVIGVGGGG SNAVNRMINS DLDGVTYRVL
60 70 80 90 100
NTDAQALIQS SATHRVQLGQ SLTRGLGAGG NPSIGQKAAE ESRADLQQAL
110 120 130 140 150
EGVDLVFIAA GMGGGTGTGA APVVAQVAKE SGALTVGIVT KPFSFEGKRR
160 170 180 190 200
LRQADEGIAR LAENVDTLIV IPNDRLKDVI SGAPLQEAFR SADDVLMKGV
210 220 230 240 250
QGISDIITCP GLVNVDFADV RSVMTEAGTA LLGIGLGSGR SRALEAAQAA
260 270 280 290 300
INSPLLEAAR IDGAKGCVIN ITGGKDMTLE DMTSASEVIS DVVDPEANII
310 320 330 340 350
VGTVVDEKLE GEIQVTVIAT GFDSNQIYSN ERNRARLSPK SLYEQPEERE
360
AGASIPEFLR LRQNR
Length:365
Mass (Da):38,144
Last modified:September 13, 2005 - v1
Checksum:iCFA2273A5B06C954
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA Translation: AAZ58366.1

Genome annotation databases

EnsemblBacteriaiAAZ58366; AAZ58366; PMN2A_0875
KEGGipmn:PMN2A_0875

Similar proteinsi

Entry informationi

Entry nameiQ46JG2_PROMT
AccessioniPrimary (citable) accession number: Q46JG2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health