Q46JC9 (Q46JC9_PROMT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase EMBL AAZ58399.1
EC=3.5.1.- EMBL AAZ58399.1

Gene names

Ordered Locus Names:

PMN2A_0908

Organism

Prochlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP] EMBL AAZ58399.1

Taxonomic identifier

59920 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	281 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS015870
Catalytic activity	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + H2O = UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine + acetate. SAAS SAAS015870
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6. SAAS SAAS015870

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS015870 Lipid synthesis
Molecular function	Hydrolase SAAS SAAS015870 EMBL AAZ58399.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q46JC9 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 4C9639E8A94993E7	FASTA	281	30,662
	10 20 30 40 50 60 MFSFPDDYEE GWTLQNEIKK DGIGLHTGLK CTVIIKPTEL TGFHISFSSE PNKVTPIDIS 70 80 90 100 110 120 QVRNTPLCTT LDLNGKKVAT VEHLLASLLG AGLTHAHIEI TGSEIPLLDG SAIGWIEEIQ 130 140 150 160 170 180 NVGMINSITS PRPRPELKSP IFVSKGESVI FAIPSEKLKL VGLIDFPYKA IGQQMFSIEL 190 200 210 220 230 240 SPNNFVKEIA PARTFGFLDQ LEELKKAGLI KGGALENALV CNGDSWVNPP LRFANEPVRH 250 260 270 280 KLLDLIGDLA FVGLPKAQIF VYKGSHALHA EFAASLKKVL T

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000095 Genomic DNA. Translation: AAZ58399.1.
RefSeq	YP_292102.1. NC_007335.2.
3D structure databases
ProteinModelPortal	Q46JC9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q46JC9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3606293.
GenomeReviews	Gene locus PMN2A_0908 in contig CP000095_GR.
KEGG	pmn:PMN2A_0908.
PATRIC	23025617. VBIProMar14922_1737.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0774.
HOGENOM	HBG482342.
OMA	KAYKSGH.
PhylomeDB	Q46JC9.
ProtClustDB	PRK13186.
Enzyme and pathway databases
BioCyc	PMAR59920:PMN2A_0908-MONOMER.
Family and domain databases
InterPro	IPR020568. Ribosomal_S5_D2-typ_fold. IPR004463. UDP-acyl_GlcNac_deAcase. IPR011334. UDP-acyl_GlcNac_deAcase_C. IPR015870. UDP-acyl_N-AcGlcN_deAcase_N. [Graphical view]
Gene3D	G3DSA:3.30.1700.10. UDP-acyl_N-AcGlcN_deAcase_C. 1 hit. G3DSA:3.30.230.20. UDP-acyl_N-AcGlcN_deAcase_N. 1 hit.
KO	K02535.
Pfam	PF03331. LpxC. 1 hit. [Graphical view]
SUPFAM	SSF54211. Ribosomal_S5_D2-typ_fold. 2 hits.
TIGRFAMs	TIGR00325. LpxC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q46JC9_PROMT

Accession

Primary (citable) accession number: Q46JC9

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)