Q46J18 (RPIA_PROMT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	PMN2A_1020

Organism

Prochlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP]

Taxonomic identifier

59920 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	236 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 236	236	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_1000194715

Sequences

	Sequence		Length	Mass (Da)
	Q46J18 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 575F984A51289391	FASTA	236	25,077
	10 20 30 40 50 60 MDLQNQMKKA VAQAAVDQIQ NGMILGLGSG STAALMIEAL AIKIKSGEIK DVVGVTTSFQ 70 80 90 100 110 120 GEVLASELGI PLKSLSSVSE IDLAIDGADE VNPKFQLIKG GGACHVQEKL VAALAKKFIV 130 140 150 160 170 180 VVDSTKLVEK LNLDFKLPVE VLPSAWKQVQ KTLINLGGEG NLRMAQKKAG PIVTDQGNLI 190 200 210 220 230 LDLTFRNGID KPELLESQIN NIPGVLENGL FVNLTDEVLV GKVESDVVGV ESLKKI

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NATL2A.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000095 Genomic DNA. Translation: AAZ58510.1.
RefSeq	YP_292213.1. NC_007335.2.
3D structure databases
ProteinModelPortal	Q46J18.
ModBase	Search...
Protein-protein interaction databases
STRING	Q46J18.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3606406.
GenomeReviews	Gene locus PMN2A_1020 in contig CP000095_GR.
KEGG	pmn:PMN2A_1020.
PATRIC	23025879. VBIProMar14922_1867.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	Q46J18.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	PMAR59920:PMN2A_1020-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. IPR014036. Tscrpt_reg_HTH_DeoR. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF00455. DeoR. 1 hit. PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_PROMT

Accession

Primary (citable) accession number: Q46J18

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	September 13, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program