Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q46J13

- IF2_PROMT

UniProt

Q46J13 - IF2_PROMT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Translation initiation factor IF-2

Gene

infB

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi684 – 6918GTPUniRule annotation
Nucleotide bindingi734 – 7385GTPUniRule annotation
Nucleotide bindingi788 – 7914GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: UniProtKB-HAMAP
  2. GTP binding Source: UniProtKB-KW
  3. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-1896-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-2UniRule annotation
Gene namesi
Name:infBUniRule annotation
Ordered Locus Names:PMN2A_1025
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11831183Translation initiation factor IF-2PRO_0000228226Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59920.PMN2A_1025.

Structurei

3D structure databases

ProteinModelPortaliQ46J13.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini675 – 847173tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni684 – 6918G1By similarity
Regioni709 – 7135G2By similarity
Regioni734 – 7374G3By similarity
Regioni788 – 7914G4By similarity
Regioni824 – 8263G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0532.
HOGENOMiHOG000076906.
KOiK02519.
OMAiQNRQGVP.
OrthoDBiEOG67HJSV.
PhylomeDBiQ46J13.

Family and domain databases

Gene3Di3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00100_B. IF_2_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view]
PANTHERiPTHR23115:SF41. PTHR23115:SF41. 1 hit.
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46J13-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTSSGKIRIY ELSKDLSLDN KDVLDAARKL AIAAKSHSSS ISSLEANQIK
60 70 80 90 100
DFLKKSNTIN TTIKSSKNLD KQILSVKKNP VKTQKDQKTE PKKKNHDQTE
110 120 130 140 150
LSQAKLNTLL KPSQTLIKSQ GSSQANNQKA LKNKFPAKQQ ITSPSKPNKP
160 170 180 190 200
LPPNPRVEVK PIISKPLTQA ERAIPQSEQK KDGQFINQPK RSELAKKSIG
210 220 230 240 250
QPKQINPQEP KRPLAPPSRP KIDIQDKKPL QPNNQKAKTR INQGEISPQK
260 270 280 290 300
VGQGNIQKIK SQNKQNAPSR TPQPPTKGNT LELVGAPIRK EKPVNKPHTN
310 320 330 340 350
EVRNKPVMPS RPGAPKPPTA ANRQGLSNRP GSNNRIGGTG RPGSPNRQGP
360 370 380 390 400
NRGGVANRTT QGQNRPGANN RAGAPVRSGS PNRGGMQNRP GVPTRSLGGP
410 420 430 440 450
NRSNNRPGVP SGMRKPVAPS ELMQLQKPQA RPNAPQRKTD SPTSLRPKRE
460 470 480 490 500
NSTGARPPVN RPTPAAPKKP AHRPGGTAAA PRRTGRPDWD DSAKLDALRN
510 520 530 540 550
KSPQKQRQKV HIIGENDDAL TAERGGFAGE QQAVVLSASL ARPSKPKVGK
560 570 580 590 600
RNNGKPLTAL KKRKKETTRQ RQRRRAMELR ASREAKLVRP EMIVVPEDNL
610 620 630 640 650
TVQELADMLS VESSEIIKSL FFKGITATVT QSLDLATIET VAEEFGVPVL
660 670 680 690 700
QDDVEEAAKK TVEMIEEGDL KYLIRRPPVV TVMGHVDHGK TSLLDAIRKA
710 720 730 740 750
RVAAGEAGGI TQHIGAYQIE TEHDGSTKKL TFLDTPGHEA FTAMRARGTR
760 770 780 790 800
VTDVAILVVA ADDGVRPQTL EAISHARAAK VPIVVAINKI DKEGSSPDRV
810 820 830 840 850
KQELSEQDLL SEEWGGDVVM VPVSAIKGEN IDKLLEMVLL VTEVEDLQAN
860 870 880 890 900
PDRLAKGTVI EAHLDKAKGP VATLLVQNGT LKSGDVVAAG PVLGKVRAMV
910 920 930 940 950
DENGSRIKEA GPSCPVEALG FSEVPTAGDE FEVYPDEKAA RAVVGERATD
960 970 980 990 1000
ARAARLAQQM ASRRVSLSSM SGQASEGELK ELNIILKADV QGSLEAILGS
1010 1020 1030 1040 1050
LEQLPKDEVQ VRVLLSAPGE ITETDIDLAA ASGAVIVGFN TSMASGAKRA
1060 1070 1080 1090 1100
ADANGVDVRE YEVIYKLLED IQLAMEGLLE PEMIEEALGV AEVRAIFSIG
1110 1120 1130 1140 1150
KSAVAGCYVT NGKIQRNCRA RVKRGKQIVF EGDLDSLKRN KDDVKDVSTG
1160 1170 1180
FECGIGCDRF ANWEEGDQIE AFKLVTQRRK LNN
Length:1,183
Mass (Da):128,121
Last modified:September 13, 2005 - v1
Checksum:i7ECFDD0DC206B4C0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ58515.1.
RefSeqiYP_292218.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ58515; AAZ58515; PMN2A_1025.
GeneIDi3606411.
KEGGipmn:PMN2A_1025.
PATRICi23025889. VBIProMar14922_1872.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ58515.1 .
RefSeqi YP_292218.1. NC_007335.2.

3D structure databases

ProteinModelPortali Q46J13.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59920.PMN2A_1025.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ58515 ; AAZ58515 ; PMN2A_1025 .
GeneIDi 3606411.
KEGGi pmn:PMN2A_1025.
PATRICi 23025889. VBIProMar14922_1872.

Phylogenomic databases

eggNOGi COG0532.
HOGENOMi HOG000076906.
KOi K02519.
OMAi QNRQGVP.
OrthoDBi EOG67HJSV.
PhylomeDBi Q46J13.

Enzyme and pathway databases

BioCyci PMAR59920:GI1O-1896-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10050. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00100_B. IF_2_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR006847. IF2_N.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000178. TF_IF2_bacterial-like.
IPR015760. TIF_IF2.
IPR023115. TIF_IF2_dom3.
IPR009000. Transl_B-barrel.
IPR004161. Transl_elong_EFTu/EF1A_2.
[Graphical view ]
PANTHERi PTHR23115:SF41. PTHR23115:SF41. 1 hit.
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF11987. IF-2. 1 hit.
PF04760. IF2_N. 2 hits.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 2 hits.
SSF52156. SSF52156. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00487. IF-2. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEi PS51722. G_TR_2. 1 hit.
PS01176. IF2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2A.

Entry informationi

Entry nameiIF2_PROMT
AccessioniPrimary (citable) accession number: Q46J13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3