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Q46IU0

- Q46IU0_PROMT

UniProt

Q46IU0 - Q46IU0_PROMT

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Protein

Alanine racemase

Gene

PMN2A_1098

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotation

Cofactori

Pyridoxal phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei63 – 631Proton acceptor; specific for D-alanineUniRule annotation
Binding sitei162 – 1621SubstrateUniRule annotation
Active sitei295 – 2951Proton acceptor; specific for L-alanineUniRule annotation
Binding sitei343 – 3431Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-1983-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:PMN2A_1098Imported
OrganismiProchlorococcus marinus (strain NATL2A)Imported
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei63 – 631N6-(pyridoxal phosphate)lysineUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi59920.PMN2A_1098.

Structurei

3D structure databases

ProteinModelPortaliQ46IU0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the alanine racemase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0787.
HOGENOMiHOG000031444.
KOiK01775.
OMAiIYSHLAL.
OrthoDBiEOG6PP9NJ.
PhylomeDBiQ46IU0.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46IU0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQSMSKINRT ERSFTFGGLT ENVITPDPRS RAWVEVDSKI IENNARVLKN
60 70 80 90 100
FIGDDCSLMA VVKADGYGHG AETVAKSALT GGADSLGVAT LEEGIQLRNA
110 120 130 140 150
GLKCQILILG NLINSEELYS SFCWDLIPTI SGIREAIICN NIAENKNKKF
160 170 180 190 200
AIHLKIDTGM TRLGCNCNQF KELINKIDCL ENIALEGIYS HLAIADRYLE
210 220 230 240 250
NNTQLSFTQI QLNRFEKVLK GLGKRNKFIC RHLANSAGTL SDSRLHFDMV
260 270 280 290 300
RVGLSLYGYF PVNDFKSDLK LSPALKVKAR VTLVRDVGKG IGVGYGHFFK
310 320 330 340 350
TQRASKLAVV AIGYADGVSR SLSGKISASI DGVLVPQVGA IAMDQMVFDI
360 370 380 390 400
TDKPDIKTGQ VLTLLGTDGE VCISPQDWCD LSGSIPWEVL CSFRNRLPRV

VT
Length:402
Mass (Da):44,043
Last modified:September 13, 2005 - v1
Checksum:i5BFF8D899E382EEB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ58588.1.
RefSeqiWP_011295442.1. NC_007335.2.
YP_292291.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ58588; AAZ58588; PMN2A_1098.
GeneIDi3606486.
KEGGipmn:PMN2A_1098.
PATRICi23026075. VBIProMar14922_1963.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ58588.1 .
RefSeqi WP_011295442.1. NC_007335.2.
YP_292291.1. NC_007335.2.

3D structure databases

ProteinModelPortali Q46IU0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59920.PMN2A_1098.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ58588 ; AAZ58588 ; PMN2A_1098 .
GeneIDi 3606486.
KEGGi pmn:PMN2A_1098.
PATRICi 23026075. VBIProMar14922_1963.

Phylogenomic databases

eggNOGi COG0787.
HOGENOMi HOG000031444.
KOi K01775.
OMAi IYSHLAL.
OrthoDBi EOG6PP9NJ.
PhylomeDBi Q46IU0.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci PMAR59920:GI1O-1983-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2AImported.

Entry informationi

Entry nameiQ46IU0_PROMT
AccessioniPrimary (citable) accession number: Q46IU0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3