SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q46HD3

- TRMB_PROMT

UniProt

Q46HD3 - TRMB_PROMT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
tRNA (guanine-N(7)-)-methyltransferase
Gene
trmB, PMN2A_1607
Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA By similarity.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei35 – 351S-adenosyl-L-methionine By similarity
Binding sitei60 – 601S-adenosyl-L-methionine By similarity
Binding sitei87 – 871S-adenosyl-L-methionine By similarity
Active sitei113 – 1131 By similarity
Binding sitei113 – 1131S-adenosyl-L-methionine By similarity
Binding sitei117 – 1171Substrate By similarity
Binding sitei149 – 1491Substrate By similarity

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-305-MONOMER.
UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferase (EC:2.1.1.33)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferase
tRNA(m7G46)-methyltransferase
Gene namesi
Name:trmB
Ordered Locus Names:PMN2A_1607
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 214214tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation
PRO_0000229183Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi59920.PMN2A_1607.

Structurei

3D structure databases

ProteinModelPortaliQ46HD3.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0220.
HOGENOMiHOG000237936.
KOiK03439.
OMAiVIQPEFI.
OrthoDBiEOG6K6VBC.
PhylomeDBiQ46HD3.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46HD3-1 [UniParc]FASTAAdd to Basket

« Hide

MRQHVNPLSQ FFQLPLSLPS KNILFEKSHY PIHLDIGSAK GEFLIELATK    50
CPDWNFVGLE IREPLVSLCE KKRRKLELTN LKFLFCNVNV SLDEWLSDLD 100
FGQLKRVSIQ FPDPWFKRKH FKRRVLKTNI LNSIAKAMSK NGEIFIQSDI 150
FELIEYMTNT IDENRYFTRK NVGDLRSINK NPYNVMTDRE ILSLKKNLLI 200
YRVMYIRNSL LFTN 214
Length:214
Mass (Da):25,364
Last modified:September 13, 2005 - v1
Checksum:i6DC375BF49429FDA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ59095.1.
RefSeqiYP_292798.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ59095; AAZ59095; PMN2A_1607.
GeneIDi3607006.
KEGGipmn:PMN2A_1607.
PATRICi23022697. VBIProMar14922_0306.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ59095.1 .
RefSeqi YP_292798.1. NC_007335.2.

3D structure databases

ProteinModelPortali Q46HD3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59920.PMN2A_1607.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ59095 ; AAZ59095 ; PMN2A_1607 .
GeneIDi 3607006.
KEGGi pmn:PMN2A_1607.
PATRICi 23022697. VBIProMar14922_0306.

Phylogenomic databases

eggNOGi COG0220.
HOGENOMi HOG000237936.
KOi K03439.
OMAi VIQPEFI.
OrthoDBi EOG6K6VBC.
PhylomeDBi Q46HD3.

Enzyme and pathway databases

UniPathwayi UPA00989 .
BioCyci PMAR59920:GI1O-305-MONOMER.

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2A.

Entry informationi

Entry nameiTRMB_PROMT
AccessioniPrimary (citable) accession number: Q46HD3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: September 13, 2005
Last modified: July 9, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi