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Q46HC4

- PTH_PROMT

UniProt

Q46HC4 - PTH_PROMT

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Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

Catalytic activityi

N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPMAR59920:GI1O-314-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
Short name:
PTHUniRule annotation
Gene namesi
Name:pthUniRule annotation
Ordered Locus Names:PMN2A_1616
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
ProteomesiUP000002535: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202Peptidyl-tRNA hydrolasePRO_0000264076Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi59920.PMN2A_1616.

Structurei

3D structure databases

ProteinModelPortaliQ46HC4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PTH family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0193.
HOGENOMiHOG000004797.
KOiK01056.
OMAiAMHRLHS.
OrthoDBiEOG6C5RTR.
PhylomeDBiQ46HC4.

Family and domain databases

Gene3Di3.40.50.1470. 1 hit.
HAMAPiMF_00083. Pept_tRNA_hydro_bact.
InterProiIPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view]
PANTHERiPTHR17224. PTHR17224. 1 hit.
PfamiPF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view]
SUPFAMiSSF53178. SSF53178. 1 hit.
TIGRFAMsiTIGR00447. pth. 1 hit.
PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46HC4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSDELKLLV GLGNPGTEYE KTRHNVGFMV LEEIARKNNC SFRESKKLFG
60 70 80 90 100
RTCEYGSGIE KTRLLMPNTY MNESGKSVRS AKDWFDFQNN QLIVLVDDMD
110 120 130 140 150
LPLGKIRVRS KGSSGGHNGL KSIINHLGTA EFKRLKIGIG APSNDQQERK
160 170 180 190 200
SKTVSHVLGR FSKEEFIILN FIIQEIISCI ESITSNNWEK ISTRLNSYKP

DN
Length:202
Mass (Da):22,873
Last modified:September 13, 2005 - v1
Checksum:i20769B5DCA06EBC4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ59104.1.
RefSeqiYP_292807.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ59104; AAZ59104; PMN2A_1616.
GeneIDi3607015.
KEGGipmn:PMN2A_1616.
PATRICi23022715. VBIProMar14922_0315.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000095 Genomic DNA. Translation: AAZ59104.1 .
RefSeqi YP_292807.1. NC_007335.2.

3D structure databases

ProteinModelPortali Q46HC4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 59920.PMN2A_1616.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ59104 ; AAZ59104 ; PMN2A_1616 .
GeneIDi 3607015.
KEGGi pmn:PMN2A_1616.
PATRICi 23022715. VBIProMar14922_0315.

Phylogenomic databases

eggNOGi COG0193.
HOGENOMi HOG000004797.
KOi K01056.
OMAi AMHRLHS.
OrthoDBi EOG6C5RTR.
PhylomeDBi Q46HC4.

Enzyme and pathway databases

BioCyci PMAR59920:GI1O-314-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1470. 1 hit.
HAMAPi MF_00083. Pept_tRNA_hydro_bact.
InterProi IPR001328. Pept_tRNA_hydro.
IPR018171. Pept_tRNA_hydro_CS.
[Graphical view ]
PANTHERi PTHR17224. PTHR17224. 1 hit.
Pfami PF01195. Pept_tRNA_hydro. 1 hit.
[Graphical view ]
SUPFAMi SSF53178. SSF53178. 1 hit.
TIGRFAMsi TIGR00447. pth. 1 hit.
PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: NATL2A.

Entry informationi

Entry nameiPTH_PROMT
AccessioniPrimary (citable) accession number: Q46HC4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: October 29, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3