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Q46HC4

- PTH_PROMT

UniProt

Q46HC4 - PTH_PROMT

Protein

Peptidyl-tRNA hydrolase

Gene

pth

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (13 Sep 2005)
      Previous versions | rss
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    • Comment

    Functioni

    The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.UniRule annotation

    Catalytic activityi

    N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.UniRule annotation

    GO - Molecular functioni

    1. aminoacyl-tRNA hydrolase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPMAR59920:GI1O-314-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptidyl-tRNA hydrolaseUniRule annotation (EC:3.1.1.29UniRule annotation)
    Short name:
    PTHUniRule annotation
    Gene namesi
    Name:pthUniRule annotation
    Ordered Locus Names:PMN2A_1616
    OrganismiProchlorococcus marinus (strain NATL2A)
    Taxonomic identifieri59920 [NCBI]
    Taxonomic lineageiBacteriaCyanobacteriaProchloralesProchlorococcaceaeProchlorococcus
    ProteomesiUP000002535: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 202202Peptidyl-tRNA hydrolasePRO_0000264076Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi59920.PMN2A_1616.

    Structurei

    3D structure databases

    ProteinModelPortaliQ46HC4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PTH family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0193.
    HOGENOMiHOG000004797.
    KOiK01056.
    OMAiAMHRLHS.
    OrthoDBiEOG6C5RTR.
    PhylomeDBiQ46HC4.

    Family and domain databases

    Gene3Di3.40.50.1470. 1 hit.
    HAMAPiMF_00083. Pept_tRNA_hydro_bact.
    InterProiIPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view]
    PANTHERiPTHR17224. PTHR17224. 1 hit.
    PfamiPF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view]
    SUPFAMiSSF53178. SSF53178. 1 hit.
    TIGRFAMsiTIGR00447. pth. 1 hit.
    PROSITEiPS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q46HC4-1 [UniParc]FASTAAdd to Basket

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    MLSDELKLLV GLGNPGTEYE KTRHNVGFMV LEEIARKNNC SFRESKKLFG    50
    RTCEYGSGIE KTRLLMPNTY MNESGKSVRS AKDWFDFQNN QLIVLVDDMD 100
    LPLGKIRVRS KGSSGGHNGL KSIINHLGTA EFKRLKIGIG APSNDQQERK 150
    SKTVSHVLGR FSKEEFIILN FIIQEIISCI ESITSNNWEK ISTRLNSYKP 200
    DN 202
    Length:202
    Mass (Da):22,873
    Last modified:September 13, 2005 - v1
    Checksum:i20769B5DCA06EBC4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000095 Genomic DNA. Translation: AAZ59104.1.
    RefSeqiYP_292807.1. NC_007335.2.

    Genome annotation databases

    EnsemblBacteriaiAAZ59104; AAZ59104; PMN2A_1616.
    GeneIDi3607015.
    KEGGipmn:PMN2A_1616.
    PATRICi23022715. VBIProMar14922_0315.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000095 Genomic DNA. Translation: AAZ59104.1 .
    RefSeqi YP_292807.1. NC_007335.2.

    3D structure databases

    ProteinModelPortali Q46HC4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 59920.PMN2A_1616.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAZ59104 ; AAZ59104 ; PMN2A_1616 .
    GeneIDi 3607015.
    KEGGi pmn:PMN2A_1616.
    PATRICi 23022715. VBIProMar14922_0315.

    Phylogenomic databases

    eggNOGi COG0193.
    HOGENOMi HOG000004797.
    KOi K01056.
    OMAi AMHRLHS.
    OrthoDBi EOG6C5RTR.
    PhylomeDBi Q46HC4.

    Enzyme and pathway databases

    BioCyci PMAR59920:GI1O-314-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.1470. 1 hit.
    HAMAPi MF_00083. Pept_tRNA_hydro_bact.
    InterProi IPR001328. Pept_tRNA_hydro.
    IPR018171. Pept_tRNA_hydro_CS.
    [Graphical view ]
    PANTHERi PTHR17224. PTHR17224. 1 hit.
    Pfami PF01195. Pept_tRNA_hydro. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53178. SSF53178. 1 hit.
    TIGRFAMsi TIGR00447. pth. 1 hit.
    PROSITEi PS01195. PEPT_TRNA_HYDROL_1. 1 hit.
    PS01196. PEPT_TRNA_HYDROL_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NATL2A.

    Entry informationi

    Entry nameiPTH_PROMT
    AccessioniPrimary (citable) accession number: Q46HC4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 12, 2006
    Last sequence update: September 13, 2005
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3