Q46H92 (Q46H92_PROMT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Enoyl-[acyl-carrier-protein] reductase [NADH] PIRNR PIRNR000094
EC=1.3.1.9 PIRNR PIRNR000094

Gene names

Ordered Locus Names:

PMN2A_1648

Organism

Prochlorococcus marinus (strain NATL2A) [Complete proteome] [HAMAP] EMBL AAZ59136.1

Taxonomic identifier

59920 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Prochlorophytes › Prochlorococcaceae › Prochlorococcus

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acyl-[acyl-carrier-protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier-protein] + NADH. PIRNR PIRNR000094
Pathway	Lipid metabolism; fatty acid biosynthesis. PIRNR PIRNR000094
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. PIRNR PIRNR000094

Ontologies

Keywords
Biological process	Fatty acid biosynthesis PIRNR PIRNR000094 Lipid synthesis
Ligand	NAD PIRNR PIRNR000094
Molecular function	Oxidoreductase PIRNR PIRNR000094 EMBL AAZ59136.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	enoyl-[acyl-carrier-protein] reductase (NADH) activity Inferred from electronic annotation. Source: EC nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	159	1	Proton acceptor By similarity PIRSR PIRSR000094-1

Sequences

	Sequence		Length	Mass (Da)
	Q46H92 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 4D9F2F027291B0E6	FASTA	260	27,711
	10 20 30 40 50 60 MLLDLSGKKI LVTGIANNRS IAWGIAQQLK AAGAELGITY LPDEKGRFET KVKELTSPLN 70 80 90 100 110 120 PSLFLPLNVQ NSSQIEEVFE AIKNQWGQLD GLVHCLAFAG KEELVGNYSA TSSEGFSRAL 130 140 150 160 170 180 EISAYSLAPL CKYAKPLFSK GAGVVTLTYL GAERAIPNYN VMGVAKAALE ASVRYLSEEL 190 200 210 220 230 240 GPENQVRVNA ISAGPIRTLA SSAIGGILDM IHNVEEKAPL RRTVTQIEVG NTAAFLLSDL 250 260 SSGISGQTVY VDAGYCINGM

References

[1]

"Patterns and implications of gene gain and loss in the evolution of Prochlorococcus." Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S., Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M., Richardson P., Chisholm S.W. PLoS Genet. 3:2515-2528(2007) [PubMed: 18159947] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000095 Genomic DNA. Translation: AAZ59136.1.
RefSeq	YP_292839.1. NC_007335.2.
3D structure databases
ProteinModelPortal	Q46H92.
ModBase	Search...
Protein-protein interaction databases
STRING	Q46H92.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3607049.
GenomeReviews	Gene locus PMN2A_1648 in contig CP000095_GR.
KEGG	pmn:PMN2A_1648.
PATRIC	23022785. VBIProMar14922_0348.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0623.
HOGENOM	HBG750976.
OMA	MILKWNE.
PhylomeDB	Q46H92.
ProtClustDB	PRK07370.
Enzyme and pathway databases
BioCyc	PMAR59920:PMN2A_1648-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR014358. Enoyl-ACP_Rdtase_NADH. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00208.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PIRSF	PIRSF000094. Enoyl-ACP_rdct. 1 hit.
PRINTS	PR00081. GDHRDH.
ProtoNet	Search...

Entry information

Entry name

Q46H92_PROMT

Accession

Primary (citable) accession number: Q46H92

Entry history

Integrated into UniProtKB/TrEMBL:	September 13, 2005
Last sequence update:	September 13, 2005
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)