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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:PMN2A_1753
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi
  • UP000002535 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003255101 – 496Probable malate:quinone oxidoreductaseAdd BLAST496

Proteomic databases

PRIDEiQ46GZ7.

Structurei

3D structure databases

ProteinModelPortaliQ46GZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000109379.
KOiK00116.
OrthoDBiPOG091H0B7C.
PhylomeDBiQ46GZ7.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 1 hit.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46GZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNTGTPDSE NTYDAILVGA GIMSSTLAVL LHELEPDLRL LVVEKLSSAG
60 70 80 90 100
LESSCAKNNA GTGHAANCEL NYTPIQEDGH LSTTKAFEIN KSFEQSLEFW
110 120 130 140 150
ASLAEKGKLI PKTFLNKLPH ISLVFGDEDI SLLKKRFSKL SSHAAFAKME
160 170 180 190 200
FTMDHGELQD WIPLIMDGRK QSEKIAATRI KRGTDIDFGN LTRSYINQIE
210 220 230 240 250
GAKSIDINYS TNVENLQQDS EGDWYLSLEG AKKNRIVRSK FVFLGAGGGA
260 270 280 290 300
LSLLQKSRIP EGLLYAGFPV SGKWLICDEE KSTKTHNAKV YGKAAVGAPP
310 320 330 340 350
MSVPHLDTRW IDKKKSLLFG PFAGFSSNFL KYGSKLDLFR SIKTTNLFSM
360 370 380 390 400
LQAGLDNIDL GKYLLNQLIQ TNEDRIDTLK RFLPQVSPND WKLSTAGQRV
410 420 430 440 450
QIIKQTSKGG VLKMGTEVVT SSDGSLAALL GASPGASTAV TIMIEVLNRC
460 470 480 490
WQEKMKSSKW KNKMLELFPS IGTDINSDQE ALLAIRKRND FLLKLI
Length:496
Mass (Da):54,782
Last modified:March 18, 2008 - v2
Checksum:i069FCF8FDAC8A3C3
GO

Sequence cautioni

The sequence AAZ59241 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA. Translation: AAZ59241.1. Different initiation.
RefSeqiWP_041710934.1. NC_007335.2.

Genome annotation databases

EnsemblBacteriaiAAZ59241; AAZ59241; PMN2A_1753.
KEGGipmn:PMN2A_1753.

Similar proteinsi

Entry informationi

Entry nameiMQO_PROMT
AccessioniPrimary (citable) accession number: Q46GZ7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 25, 2017
This is version 71 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families