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Protein

Guanylate kinase

Gene

gmk

Organism
Prochlorococcus marinus (strain NATL2A)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi12 – 19ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPMAR59920:G1G4T-492-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:PMN2A_1799
OrganismiProchlorococcus marinus (strain NATL2A)
Taxonomic identifieri59920 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesProchloraceaeProchlorococcus
Proteomesi

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002663681 – 186Guanylate kinaseAdd BLAST186

Structurei

3D structure databases

ProteinModelPortaliQ46GV6
SMRiQ46GV6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 183Guanylate kinase-likeUniRule annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037640
KOiK00942
OMAiAGNYYGT
OrthoDBiPOG091H01Q4
PhylomeDBiQ46GV6

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q46GV6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLGNLTVL TGPSGVGKGT IVRKILESHS DVWLSISATT RQPRSGEIDG
60 70 80 90 100
EHYFFLEKKQ FQEIIDKDGF LEWASFSNNF YGTPKKIVKE KIEKGTNVLL
110 120 130 140 150
EIELEGARQI RKSFPEAFQI FLAPPNLYEL EKRIRGRGTE TEESIRDRLS
160 170 180
IAEKELIAQK EFDAVVINED IEKAFKEIEG FMGLKL
Length:186
Mass (Da):21,155
Last modified:September 13, 2005 - v1
Checksum:iE165FFE698FE48C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000095 Genomic DNA Translation: AAZ59287.1
RefSeqiWP_011294432.1, NC_007335.2

Genome annotation databases

EnsemblBacteriaiAAZ59287; AAZ59287; PMN2A_1799
KEGGipmn:PMN2A_1799

Similar proteinsi

Entry informationi

Entry nameiKGUA_PROMT
AccessioniPrimary (citable) accession number: Q46GV6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: September 13, 2005
Last modified: March 28, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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