Reviewed, UniProtKB/Swiss-Prot Q46FV0 (KAD6_METBF)

Names and origin

Protein names

Recommended name:
    Putative adenylate kinase
    EC=2.7.4.3
Alternative name(s):
    ATP-AMP transphosphorylase

Gene names

Ordered Locus Names:

Mbar_A0258

Organism

Methanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]

Taxonomic identifier

269797 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + AMP = 2 ADP. HAMAP MF_00039
Sequence similarities	Belongs to the adenylate kinase family. AK6 subfamily.

Ontologies

Keywords
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP adenylate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 182	182	Putative adenylate kinase HAMAP MF_00039		PRO_1000003091
Regions
	Nucleotide binding	7 – 14	8	ATP Potential

Sequences

	Sequence		Length	Mass (Da)
	Q46FV0-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: 6EE6678F65AE38CA	FASTA	182	21,069
	10 20 30 40 50 60 MLIGLTGTPG TGKTSVSKFL ERKRHWKVIH LNEMIKEEHL YTEVDEVRDA VIADMELVRQ 70 80 90 100 110 120 RLEEIIGGKE NEVIILESHL AHYIADIVII LRVYPPELKM RLKARGYSEE KIRENIEAEA 130 140 150 160 170 180 LDVILVEAFE WCKKVFEINT TGKSIEETEQ HIEKIIDHIL SGNEEELPEY KPGSIDWIDL VP

References

[1]

"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes." Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R. J. Bacteriol. 188:7922-7931(2006) [PubMed: 16980466] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000099 Genomic DNA. Translation: AAZ69242.1.
RefSeq	YP_303822.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3624967.
GenomeReviews	Gene locus Mbar_A0258 in contig CP000099_GR.
KEGG	mba:Mbar_A0258.
NMPDR	fig|269797.3.peg.374.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q46FV0.
OMA	Q46FV0. RVGIVDW.
Enzyme and pathway databases
BioCyc	MBAR269797:MBAR_A0258-MON.
Family and domain databases
HAMAP	MF_00039. [Tree]
ProtoNet	Search...

Entry information

Entry name

KAD6_METBF

Accession

Primary (citable) accession number: Q46FV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	June 16, 2009
This is version 17 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)