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Protein

Putative adenylate kinase

Gene

Mbar_A0258

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates.UniRule annotation

Catalytic activityi

ATP + AMP = 2 ADP.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei101ATPUniRule annotation1
Binding sitei105ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15ATPUniRule annotation6

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Putative adenylate kinaseUniRule annotation (EC:2.7.4.3UniRule annotation)
Short name:
AKUniRule annotation
Alternative name(s):
ATP-AMP transphosphorylaseUniRule annotation
Gene namesi
Ordered Locus Names:Mbar_A0258
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000008156 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000030911 – 182Putative adenylate kinaseAdd BLAST182

Interactioni

Protein-protein interaction databases

STRINGi269797.Mbar_A0258.

Structurei

3D structure databases

ProteinModelPortaliQ46FV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni30 – 53NMPbindUniRule annotationAdd BLAST24
Regioni104 – 114LIDUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the adenylate kinase family. AK6 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01038. Archaea.
COG1936. LUCA.
HOGENOMiHOG000224471.
KOiK18532.
OMAiVDWSEVY.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00039. Adenylate_kinase_AK6. 1 hit.
InterProiIPR020618. Adenyl_kinase_AK6.
IPR027417. P-loop_NTPase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46FV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLIGLTGTPG TGKTSVSKFL ERKRHWKVIH LNEMIKEEHL YTEVDEVRDA
60 70 80 90 100
VIADMELVRQ RLEEIIGGKE NEVIILESHL AHYIADIVII LRVYPPELKM
110 120 130 140 150
RLKARGYSEE KIRENIEAEA LDVILVEAFE WCKKVFEINT TGKSIEETEQ
160 170 180
HIEKIIDHIL SGNEEELPEY KPGSIDWIDL VP
Length:182
Mass (Da):21,069
Last modified:September 13, 2005 - v1
Checksum:i6EE6678F65AE38CA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ69242.1.
RefSeqiWP_011305297.1. NC_007355.1.

Genome annotation databases

EnsemblBacteriaiAAZ69242; AAZ69242; Mbar_A0258.
GeneIDi3624967.
KEGGimba:Mbar_A0258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ69242.1.
RefSeqiWP_011305297.1. NC_007355.1.

3D structure databases

ProteinModelPortaliQ46FV0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi269797.Mbar_A0258.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAZ69242; AAZ69242; Mbar_A0258.
GeneIDi3624967.
KEGGimba:Mbar_A0258.

Phylogenomic databases

eggNOGiarCOG01038. Archaea.
COG1936. LUCA.
HOGENOMiHOG000224471.
KOiK18532.
OMAiVDWSEVY.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00039. Adenylate_kinase_AK6. 1 hit.
InterProiIPR020618. Adenyl_kinase_AK6.
IPR027417. P-loop_NTPase.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiKAD6_METBF
AccessioniPrimary (citable) accession number: Q46FV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: November 2, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.