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Q46EL9 (IF5A_METBF) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Translation initiation factor 5A
Alternative name(s):
Hypusine-containing protein
eIF-5A
Gene names
Name:eif5a
Ordered Locus Names:Mbar_A0695
OrganismMethanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]
Taxonomic identifier269797 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Functions by promoting the formation of the first peptide bond By similarity. HAMAP-Rule MF_00085

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00085.

Sequence similarities

Belongs to the eIF-5A family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 128128Translation initiation factor 5A HAMAP-Rule MF_00085
PRO_0000259437

Amino acid modifications

Modified residue351Hypusine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q46EL9 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 3A6467D6506BC5F4

FASTA12814,238
        10         20         30         40         50         60 
MKQQVEVKEL KEGKYVIIDD EACVIKSITK SKPGKHGAAK ARVEAIGLFD GQKRSYIGSV 

        70         80         90        100        110        120 
ANKIYVPIVE RKTAQVISIT GDITQLMDMG DFSTFEIVVP DEYKDKIKEG EEVSYITALG 


KIKLDIRT 

« Hide

References

[1]"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fusaro / DSM 804.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000099 Genomic DNA. Translation: AAZ69673.1.
RefSeqYP_304253.1. NC_007355.1.

3D structure databases

ProteinModelPortalQ46EL9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269797.Mbar_A0695.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ69673; AAZ69673; Mbar_A0695.
GeneID3625762.
KEGGmba:Mbar_A0695.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0231.
HOGENOMHOG000106269.
KOK03263.
OMAVEVWQIL.
ProtClustDBPRK03999.

Enzyme and pathway databases

BioCycMBAR269797:GHUW-710-MONOMER.

Family and domain databases

Gene3D2.30.30.30. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00085. eIF_5A.
InterProIPR012340. NA-bd_OB-fold.
IPR014722. Rib_L2_dom2.
IPR019769. Trans_elong_IF5A_hypusine_site.
IPR001884. Transl_elong_IF5A.
IPR022847. Transl_elong_IF5A_arc.
IPR020189. Transl_elong_IF5A_C.
IPR008991. Translation_prot_SH3-like.
[Graphical view]
PANTHERPTHR11673. PTHR11673. 1 hit.
PTHR11673:SF1. PTHR11673:SF1. 1 hit.
PfamPF01287. eIF-5a. 1 hit.
[Graphical view]
PIRSFPIRSF003025. eIF5A. 1 hit.
SUPFAMSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00037. eIF_5A. 1 hit.
PROSITEPS00302. IF5A_HYPUSINE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF5A_METBF
AccessionPrimary (citable) accession number: Q46EL9
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: September 13, 2005
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries