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Q46E27 (Q46E27_METBF) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferase HAMAP-Rule MF_00210
EC=2.5.1.19 HAMAP-Rule MF_00210
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase HAMAP-Rule MF_00210
Gene names
Name:aroA HAMAP-Rule MF_00210
Ordered Locus Names:Mbar_A0891 EMBL AAZ69865.1
OrganismMethanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP] EMBL AAZ69865.1
Taxonomic identifier269797 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina ›

Protein attributes

Sequence length443 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP-Rule MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP-Rule MF_00210 RuleBase RU004116

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00210

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00210.

Sequence similarities

Belongs to the EPSP synthase family. HAMAP-Rule MF_00210 RuleBase RU004164

Sequences

Sequence LengthMass (Da)Tools
Q46E27 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 0922FCDE57D7B94C

FASTA44347,678
        10         20         30         40         50         60 
MKNPIRNRRD LIHMRVSIDK SSIKGEVFAP PSKSYTHRAV TLAALSKEST VRHPLISADT 

        70         80         90        100        110        120 
LATVRASEMF GALVEREEDR LIIHGINGKP NVPDDVIDAA NSGTTLRFMT AVAALTDGIT 

       130        140        150        160        170        180 
VLTGDASLRT RPNGPLLEVL NRLGVKACST RGNERAPLVV KGGLKGQDVS IDGSISSQFI 

       190        200        210        220        230        240 
SALLITCPLA ENSTILSITG KIKSRPYVDI TLEMLELAGV KVHIDDSNGT RFIIPGKQKY 

       250        260        270        280        290        300 
DFKDYTVPGD FSSASYLLAA AAMTDGSEVT VKNLFPSKQG DKVIIETLKQ MGADITWDKE 

       310        320        330        340        350        360 
AGNVTVKGGR QLKAITFDAG ANPDLVPTVA VLAAVAKGTS RIENAEHVRY KETDRLRALA 

       370        380        390        400        410        420 
TELPKLGVDL KEERDSLTIT GGKLHGASVH GWDDHRIVMA LSVAGIVAGN TKIDTTESAS 

       430        440 
ISYPEFFKDM RSLGAKIKDF SKE

« Hide

References

[1]"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fusaro / DSM 804.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000099 Genomic DNA. Translation: AAZ69865.1.
RefSeqYP_304445.1. NC_007355.1.

3D structure databases

ProteinModelPortalQ46E27.
ModBaseSearch...

Protein-protein interaction databases

STRING269797.Mbar_A0891.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ69865; AAZ69865; Mbar_A0891.
GeneID3625936.
KEGGmba:Mbar_A0891.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHOG000247372.
KOK00800.
OMASNAGPFL.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycMBAR269797:GHUW-963-MONOMER.
UniPathwayUPA00053; UER00089.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00210. EPSP_synth.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. aroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ46E27_METBF
AccessionPrimary (citable) accession number: Q46E27
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 1, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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