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Q46E27

- Q46E27_METBF

UniProt

Q46E27 - Q46E27_METBF

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Protein

Probable 3-phosphoshikimate 1-carboxyvinyltransferase

Gene

aroA

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-phosphoshikimate 1-carboxyvinyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-KW
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-905-MONOMER.
UniPathwayiUPA00053; UER00089.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.19UniRule annotation)
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthaseUniRule annotation
Gene namesi
Name:aroAUniRule annotation
Ordered Locus Names:Mbar_A0891Imported
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)Imported
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000008156: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi269797.Mbar_A0891.

Structurei

3D structure databases

ProteinModelPortaliQ46E27.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the EPSP synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0128.
HOGENOMiHOG000247372.
KOiK00800.
OMAiSYDDHRM.

Family and domain databases

Gene3Di3.65.10.10. 2 hits.
HAMAPiMF_00210. EPSP_synth.
InterProiIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
PfamiPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF000505. EPSPS. 1 hit.
SUPFAMiSSF55205. SSF55205. 1 hit.
TIGRFAMsiTIGR01356. aroA. 1 hit.
PROSITEiPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46E27-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKNPIRNRRD LIHMRVSIDK SSIKGEVFAP PSKSYTHRAV TLAALSKEST
60 70 80 90 100
VRHPLISADT LATVRASEMF GALVEREEDR LIIHGINGKP NVPDDVIDAA
110 120 130 140 150
NSGTTLRFMT AVAALTDGIT VLTGDASLRT RPNGPLLEVL NRLGVKACST
160 170 180 190 200
RGNERAPLVV KGGLKGQDVS IDGSISSQFI SALLITCPLA ENSTILSITG
210 220 230 240 250
KIKSRPYVDI TLEMLELAGV KVHIDDSNGT RFIIPGKQKY DFKDYTVPGD
260 270 280 290 300
FSSASYLLAA AAMTDGSEVT VKNLFPSKQG DKVIIETLKQ MGADITWDKE
310 320 330 340 350
AGNVTVKGGR QLKAITFDAG ANPDLVPTVA VLAAVAKGTS RIENAEHVRY
360 370 380 390 400
KETDRLRALA TELPKLGVDL KEERDSLTIT GGKLHGASVH GWDDHRIVMA
410 420 430 440
LSVAGIVAGN TKIDTTESAS ISYPEFFKDM RSLGAKIKDF SKE
Length:443
Mass (Da):47,678
Last modified:September 13, 2005 - v1
Checksum:i0922FCDE57D7B94C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ69865.1.
RefSeqiYP_304445.1. NC_007355.1.

Genome annotation databases

EnsemblBacteriaiAAZ69865; AAZ69865; Mbar_A0891.
GeneIDi3625936.
KEGGimba:Mbar_A0891.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ69865.1 .
RefSeqi YP_304445.1. NC_007355.1.

3D structure databases

ProteinModelPortali Q46E27.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269797.Mbar_A0891.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ69865 ; AAZ69865 ; Mbar_A0891 .
GeneIDi 3625936.
KEGGi mba:Mbar_A0891.

Phylogenomic databases

eggNOGi COG0128.
HOGENOMi HOG000247372.
KOi K00800.
OMAi SYDDHRM.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00089 .
BioCyci MBAR269797:GHUW-905-MONOMER.

Family and domain databases

Gene3Di 3.65.10.10. 2 hits.
HAMAPi MF_00210. EPSP_synth.
InterProi IPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view ]
Pfami PF00275. EPSP_synthase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000505. EPSPS. 1 hit.
SUPFAMi SSF55205. SSF55205. 1 hit.
TIGRFAMsi TIGR01356. aroA. 1 hit.
PROSITEi PS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
    Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
    J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fusaro / DSM 804Imported.

Entry informationi

Entry nameiQ46E27_METBF
AccessioniPrimary (citable) accession number: Q46E27
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: October 1, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3