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Q46E27

- Q46E27_METBF

UniProt

Q46E27 - Q46E27_METBF

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Protein
Probable 3-phosphoshikimate 1-carboxyvinyltransferase
Gene
aroA, Mbar_A0891
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 3-phosphoshikimate 1-carboxyvinyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. aromatic amino acid family biosynthetic process Source: UniProtKB-KW
  2. chorismate biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationImported

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesisUniRule annotation

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-905-MONOMER.
UniPathwayiUPA00053; UER00089.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable 3-phosphoshikimate 1-carboxyvinyltransferaseUniRule annotation (EC:2.5.1.19UniRule annotation)
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Gene namesi
Name:aroAUniRule annotation
Ordered Locus Names:Mbar_A0891Imported
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)Imported
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000008156: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi269797.Mbar_A0891.

Structurei

3D structure databases

ProteinModelPortaliQ46E27.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0128.
HOGENOMiHOG000247372.
KOiK00800.
OMAiSYDDHRM.

Family and domain databases

Gene3Di3.65.10.10. 2 hits.
HAMAPiMF_00210. EPSP_synth.
InterProiIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
PfamiPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF000505. EPSPS. 1 hit.
SUPFAMiSSF55205. SSF55205. 1 hit.
TIGRFAMsiTIGR01356. aroA. 1 hit.
PROSITEiPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46E27-1 [UniParc]FASTAAdd to Basket

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MKNPIRNRRD LIHMRVSIDK SSIKGEVFAP PSKSYTHRAV TLAALSKEST    50
VRHPLISADT LATVRASEMF GALVEREEDR LIIHGINGKP NVPDDVIDAA 100
NSGTTLRFMT AVAALTDGIT VLTGDASLRT RPNGPLLEVL NRLGVKACST 150
RGNERAPLVV KGGLKGQDVS IDGSISSQFI SALLITCPLA ENSTILSITG 200
KIKSRPYVDI TLEMLELAGV KVHIDDSNGT RFIIPGKQKY DFKDYTVPGD 250
FSSASYLLAA AAMTDGSEVT VKNLFPSKQG DKVIIETLKQ MGADITWDKE 300
AGNVTVKGGR QLKAITFDAG ANPDLVPTVA VLAAVAKGTS RIENAEHVRY 350
KETDRLRALA TELPKLGVDL KEERDSLTIT GGKLHGASVH GWDDHRIVMA 400
LSVAGIVAGN TKIDTTESAS ISYPEFFKDM RSLGAKIKDF SKE 443
Length:443
Mass (Da):47,678
Last modified:September 13, 2005 - v1
Checksum:i0922FCDE57D7B94C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000099 Genomic DNA. Translation: AAZ69865.1.
RefSeqiYP_304445.1. NC_007355.1.

Genome annotation databases

EnsemblBacteriaiAAZ69865; AAZ69865; Mbar_A0891.
GeneIDi3625936.
KEGGimba:Mbar_A0891.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000099 Genomic DNA. Translation: AAZ69865.1 .
RefSeqi YP_304445.1. NC_007355.1.

3D structure databases

ProteinModelPortali Q46E27.
ModBasei Search...

Protein-protein interaction databases

STRINGi 269797.Mbar_A0891.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ69865 ; AAZ69865 ; Mbar_A0891 .
GeneIDi 3625936.
KEGGi mba:Mbar_A0891.

Phylogenomic databases

eggNOGi COG0128.
HOGENOMi HOG000247372.
KOi K00800.
OMAi SYDDHRM.

Enzyme and pathway databases

UniPathwayi UPA00053 ; UER00089 .
BioCyci MBAR269797:GHUW-905-MONOMER.

Family and domain databases

Gene3Di 3.65.10.10. 2 hits.
HAMAPi MF_00210. EPSP_synth.
InterProi IPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view ]
Pfami PF00275. EPSP_synthase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000505. EPSPS. 1 hit.
SUPFAMi SSF55205. SSF55205. 1 hit.
TIGRFAMsi TIGR01356. aroA. 1 hit.
PROSITEi PS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
    Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
    J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fusaro / DSM 804.

Entry informationi

Entry nameiQ46E27_METBF
AccessioniPrimary (citable) accession number: Q46E27
Entry historyi
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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