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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Mbar_A1008
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000008156 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002421301 – 569Arginine--tRNA ligaseAdd BLAST569

Interactioni

Protein-protein interaction databases

STRINGi269797.Mbar_A1008

Structurei

3D structure databases

ProteinModelPortaliQ46DR6
SMRiQ46DR6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00487 Archaea
COG0018 LUCA
HOGENOMiHOG000247213
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG093Z013U

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

Q46DR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFLELKAQAT SILKDAIQKA GLEIEDSELY FETSSYADLA SRAAFRLASL
60 70 80 90 100
YRQNPKELAT RIVSAVEIPD GSYIGKVSAS GPYINFHASR RYMDKTVATV
110 120 130 140 150
LEEKEKFGCG APKDKILLEH TSANPNGPLH VGHIRNSIIG DTLARILRRA
160 170 180 190 200
GYDVEVQYYV NDMGRQIAVV SWACERFELD LSRKSDSAIA DVYIKANVEL
210 220 230 240 250
DKNPEYVKEI DALMEKVEAG DVKTIDSFYK AVSLAISGIK ETLLRLNVVH
260 270 280 290 300
DKFVSESTFL KSGAVHDIVE RIKATGRTKT DKGALVVDLS DYGFKKTLVI
310 320 330 340 350
QRSNGTSLYT TRDLAYHEWK AGQADRIIDI FGADHKLISG QLRATLNSIG
360 370 380 390 400
VKEPEVVIFE FVSLPEGSMS TRRGQFISAD ELFDRVTEAA LEQVETRRPE
410 420 430 440 450
TSEEFKKQVA EMVGIGAVRY DIVRVSPEKS TVFNWKEALD FEKQGAPYIQ
460 470 480 490 500
YSHARACSIL EKAKEEAAWN SSAEIDPSLL VEDTEIDLIK KMASFDRVID
510 520 530 540 550
LAARELKPHV LAIYARELAD AFNQFYRFVP VIAAEDEKVR ASRLALVNCA
560
RIVLANSLDT LGIAAPESM
Length:569
Mass (Da):63,401
Last modified:September 13, 2005 - v1
Checksum:i68F138647761DB20
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA Translation: AAZ69976.1
RefSeqiWP_011306025.1, NC_007355.1

Genome annotation databases

EnsemblBacteriaiAAZ69976; AAZ69976; Mbar_A1008
GeneIDi3625587
KEGGimba:Mbar_A1008

Similar proteinsi

Entry informationi

Entry nameiSYR_METBF
AccessioniPrimary (citable) accession number: Q46DR6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: September 13, 2005
Last modified: June 20, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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