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Q46DH9 (Q46DH9_METBF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
F420-dependent methylenetetrahydromethanopterin dehydrogenase HAMAP MF_00058
Short name=MTD HAMAP MF_00058
EC=1.5.99.9 HAMAP MF_00058
Alternative name(s):
Coenzyme F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase HAMAP MF_00058
Gene names
Name:mtd HAMAP MF_00058
Ordered Locus Names:Mbar_A1095
OrganismMethanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP] EMBL AAZ70063.1
Taxonomic identifier269797 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the reversible reduction of methenyl-H4MPT+ to methylene-H4MPT By similarity. HAMAP MF_00058

Catalytic activity

5,10-methylenetetrahydromethanopterin + coenzyme F420 = 5,10-methenyltetrahydromethanopterin + reduced coenzyme F420. HAMAP MF_00058

Pathway

One-carbon metabolism; methanogenesis from CO(2); 5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (coenzyme F420 route): step 1/1. HAMAP MF_00058

Sequence similarities

Belongs to the MTD family. HAMAP MF_00058

Sequences

Sequence LengthMass (Da)Tools
Q46DH9 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: 25EB8D430CAA967D

FASTA27629,822
        10         20         30         40         50         60 
MVNIGFIKMG NLGMSQVINL VQDEIAAREG ITVRVFGTGA KMSPAEAAAS ESFKQWNADF 

        70         80         90        100        110        120 
VIIISPNAAA PGPKAAREIW KDVPCIVVSD GPTKKEAREA LENNGFGYLI LPVDPLIGAK 

       130        140        150        160        170        180 
REFLDPVEMA SFNSDAMKVL SVCGVVRLVQ EELDKVTDQV ASGKSGKELE LPHIFAKPEK 

       190        200        210        220        230        240 
CVEYAGFANP YAKAKALAAL HMAEKVAQVN FPACFMLKEI DQVCLTAAAG HEIMGAASQL 

       250        260        270 
AIQAREIEKS NDTVLRQPHA KNGTLLKKVK LYQKPE

« Hide

References

[1]"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
J. Bacteriol. 188:7922-7931(2006) [PubMed: 16980466] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000099 Genomic DNA. Translation: AAZ70063.1.
RefSeqYP_304643.1. NC_007355.1.

3D structure databases

ProteinModelPortalQ46DH9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ46DH9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3627370.
GenomeReviewsGene locus Mbar_A1095 in contig CP000099_GR.
KEGGmba:Mbar_A1095.
NMPDRfig|269797.3.peg.1106.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGarNOG04866.
HOGENOMHBG538567.
OMANPYAKAK.
ProtClustDBPRK00994.

Family and domain databases

HAMAPMF_00058. MTD.
[Tree]
InterProIPR002844. Methylene_DH.
[Graphical view]
KOK00319.
PfamPF01993. MTD. 1 hit.
[Graphical view]
PIRSFPIRSF005627. MTD. 1 hit.
ProDomPD017604. Methylene_DH. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF102324. MeTD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ46DH9_METBF
AccessionPrimary (citable) accession number: Q46DH9
Entry history
Integrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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