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Q46D07

- RNP4_METBF

UniProt

Q46D07 - RNP4_METBF

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Protein

Ribonuclease P protein component 4

Gene
rnp4, Mbar_A1272
Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

Cofactori

Binds 1 zinc ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi66 – 661Zinc By similarity
Metal bindingi69 – 691Zinc By similarity
Metal bindingi92 – 921Zinc By similarity
Metal bindingi95 – 951Zinc By similarity

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-HAMAP
  2. zinc ion binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. tRNA 5'-leader removal Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-1300-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein component 4 (EC:3.1.26.5)
Short name:
RNase P component 4
Alternative name(s):
Rpp21
Gene namesi
Name:rnp4
Ordered Locus Names:Mbar_A1272
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000008156: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. ribonuclease P complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 107107Ribonuclease P protein component 4UniRule annotationPRO_1000046631Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component and at least 4-5 protein subunits Reviewed prediction.

Protein-protein interaction databases

STRINGi269797.Mbar_A1272.

Structurei

3D structure databases

ProteinModelPortaliQ46D07.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG2023.
HOGENOMiHOG000230709.
KOiK03540.
OMAiPRKWKRR.

Family and domain databases

HAMAPiMF_00757. RNase_P_4.
InterProiIPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view]
PANTHERiPTHR14742. PTHR14742. 1 hit.
PfamiPF04032. Rpr2. 1 hit.
[Graphical view]
PIRSFiPIRSF004878. RNase_P_4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46D07-1 [UniParc]FASTAAdd to Basket

« Hide

MSRIARKQQK NLIQAIAIQR MWRLFELAKS EYAEHPDRSE RYVQLIRNIS    50
MRNRMSIPRE IKNRICKHCY AFLVPGNNAR YRLKDGYIVV SCQRCGKEMR 100
YPYKKLK 107
Length:107
Mass (Da):12,966
Last modified:September 13, 2005 - v1
Checksum:i1E4A5CB36145DEFE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000099 Genomic DNA. Translation: AAZ70235.1.
RefSeqiWP_011306282.1. NC_007355.1.
YP_304815.1. NC_007355.1.

Genome annotation databases

EnsemblBacteriaiAAZ70235; AAZ70235; Mbar_A1272.
GeneIDi3627759.
KEGGimba:Mbar_A1272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000099 Genomic DNA. Translation: AAZ70235.1 .
RefSeqi WP_011306282.1. NC_007355.1.
YP_304815.1. NC_007355.1.

3D structure databases

ProteinModelPortali Q46D07.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269797.Mbar_A1272.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ70235 ; AAZ70235 ; Mbar_A1272 .
GeneIDi 3627759.
KEGGi mba:Mbar_A1272.

Phylogenomic databases

eggNOGi COG2023.
HOGENOMi HOG000230709.
KOi K03540.
OMAi PRKWKRR.

Enzyme and pathway databases

BioCyci MBAR269797:GHUW-1300-MONOMER.

Family and domain databases

HAMAPi MF_00757. RNase_P_4.
InterProi IPR016432. RNase_P_comp-4.
IPR007175. Rpr2.
[Graphical view ]
PANTHERi PTHR14742. PTHR14742. 1 hit.
Pfami PF04032. Rpr2. 1 hit.
[Graphical view ]
PIRSFi PIRSF004878. RNase_P_4. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
    Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
    J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fusaro / DSM 804.

Entry informationi

Entry nameiRNP4_METBF
AccessioniPrimary (citable) accession number: Q46D07
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: September 3, 2014
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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