Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

NAD(P)H dehydrogenase (quinone)

Gene

Mbar_A1914

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

Cofactori

FMNUniRule annotationNote: Binds 1 FMN per monomer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei107SubstrateUniRule annotation1
Binding sitei143FMNUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi10 – 15FMNUniRule annotation6
Nucleotide bindingi87 – 89FMNUniRule annotation3
Nucleotide bindingi122 – 128FMNUniRule annotation7

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
LigandFlavoprotein, FMN, NAD, NADP, Nucleotide-binding

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-1905-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
NAD(P)H dehydrogenase (quinone)UniRule annotation (EC:1.6.5.2UniRule annotation)
Alternative name(s):
Flavoprotein WrbA
NAD(P)H:quinone oxidoreductaseUniRule annotation
Short name:
NQOUniRule annotation
Gene namesi
Ordered Locus Names:Mbar_A1914
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
Proteomesi
  • UP000008156 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002910391 – 208NAD(P)H dehydrogenase (quinone)Add BLAST208

Interactioni

Protein-protein interaction databases

STRINGi269797.Mbar_A1914

Structurei

3D structure databases

ProteinModelPortaliQ46B88
SMRiQ46B88
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 199Flavodoxin-likeUniRule annotationAdd BLAST196

Sequence similaritiesi

Belongs to the WrbA family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG00510 Archaea
COG0655 LUCA
HOGENOMiHOG000030539
KOiK03809
OMAiVGVPYAC
OrthoDBiPOG093Z0AW5

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01017 NQOR, 1 hit
InterProiView protein in InterPro
IPR008254 Flavodoxin/NO_synth
IPR001226 Flavodoxin_CS
IPR029039 Flavoprotein-like_sf
IPR010089 Flavoprotein_WrbA-like
IPR005025 FMN_Rdtase-like
IPR037513 NQO
PfamiView protein in Pfam
PF03358 FMN_red, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit
TIGRFAMsiTIGR01755 flav_wrbA, 1 hit
PROSITEiView protein in PROSITE
PS50902 FLAVODOXIN_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

Q46B88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVKVNVIFHS IHGHTYKMAE AIAEGAREVE GAEVEIYQVP ETLPYEVLEK
60 70 80 90 100
MGAIETKNLF AHIPVVTRSM YEDVFAGADA LIFGTPTRYG NMTAQMRTVF
110 120 130 140 150
DGLGGLWSRD ALVGKVGSVF TSSGTQHGGQ ESTILTTHVT LLHLGMIIVG
160 170 180 190 200
LPYSETRQRR MDEITGGSPY GASTIAGAEE NRQPSENELA MARYQGRHVT

QIAKKLIG
Length:208
Mass (Da):22,684
Last modified:September 13, 2005 - v1
Checksum:i374AA97BDC145A3D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA Translation: AAZ70854.1
RefSeqiWP_011306900.1, NC_007355.1

Genome annotation databases

EnsemblBacteriaiAAZ70854; AAZ70854; Mbar_A1914
GeneIDi3627193
KEGGimba:Mbar_A1914

Similar proteinsi

Entry informationi

Entry nameiNQOR_METBF
AccessioniPrimary (citable) accession number: Q46B88
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: September 13, 2005
Last modified: June 20, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health