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Q469M8 (RNP3_METBF) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component 3

Short name=RNase P component 3
EC=3.1.26.5
Alternative name(s):
Rpp30
Gene names
Name:rnp3
Ordered Locus Names:Mbar_A2501
OrganismMethanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]
Taxonomic identifier269797 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00756

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00756

Subunit structure

Consists of a catalytic RNA component and at least 4-5 protein subunits Potential.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00756.

Sequence similarities

Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtRNA 5'-leader removal

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

ribonuclease P complex

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239Ribonuclease P protein component 3 HAMAP-Rule MF_00756
PRO_1000046625

Sequences

Sequence LengthMass (Da)Tools
Q469M8 [UniParc].

Last modified September 13, 2005. Version 1.
Checksum: C77F34E1D35ECE48

FASTA23926,090
        10         20         30         40         50         60 
MGKPKFYDFC VHAVPDGENT VDQLSALARH LGYSGIALTN HSDKLPQSQP VLPSTNEFEV 

        70         80         90        100        110        120 
FKGIELVEEN PSKLHGLIGK FRKSVDVLIV HGGSENVNRA ALENPRVDIL NHPAFAKSSG 

       130        140        150        160        170        180 
LNQVLAKSAA ENDVAISLII RPLLHSRGPR RVRLLSNLRA NLDLARKYDV SLVLSSGAMS 

       190        200        210        220        230 
CFDLRSPMET LALAEVCGLE EDEALEAITV VPERIISRNR PGPGHVREGI EVLEEGDYS 

« Hide

References

[1]"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Fusaro / DSM 804.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000099 Genomic DNA. Translation: AAZ71414.1.
RefSeqYP_305994.1. NC_007355.1.

3D structure databases

ProteinModelPortalQ469M8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING269797.Mbar_A2501.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAZ71414; AAZ71414; Mbar_A2501.
GeneID3625694.
KEGGmba:Mbar_A2501.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1603.
HOGENOMHOG000229552.
KOK03539.
OMAAGHEAKK.

Enzyme and pathway databases

BioCycMBAR269797:GHUW-2550-MONOMER.

Family and domain databases

HAMAPMF_00756. RNase_P_3.
InterProIPR016195. Pol/histidinol_Pase-like.
IPR023539. RNase_P_comp-3_arc.
IPR002738. RNase_P_p30.
[Graphical view]
PANTHERPTHR13031. PTHR13031. 1 hit.
PfamPF01876. RNase_P_p30. 1 hit.
[Graphical view]
SUPFAMSSF89550. SSF89550. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRNP3_METBF
AccessionPrimary (citable) accession number: Q469M8
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: September 13, 2005
Last modified: July 9, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families