Reviewed, UniProtKB/Swiss-Prot Q469M7 (RNP2_METBF)

Names and origin

Protein names

Recommended name:
    Ribonuclease P protein component 2
      Short name=RNase P component 2
    EC=3.1.26.5

Gene names

Name:	rnp2
Ordered Locus Names:	Mbar_A2502

Organism

Methanosarcina barkeri (strain Fusaro / DSM 804) [Complete proteome] [HAMAP]

Taxonomic identifier

269797 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina

Protein attributes

Sequence length	135 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity.
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP MF_00755
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 2 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 135	135	Ribonuclease P protein component 2 HAMAP MF_00755		PRO_1000046621

Sequences

	Sequence		Length	Mass (Da)
	Q469M7-1 [UniParc]. Last modified September 13, 2005. Version 1. Checksum: F37C061D863401ED	FASTA	135	15,090
	10 20 30 40 50 60 MKRLLPSLRA KKRYLAFELI SEVPVSRSDL VKEVMFSASS LLGDVTASEC DIKVLGFEES 70 80 90 100 110 120 KGIIQCAHTK VKETRASMAT LTRINGKRAT VHILGTSGTI KRATEKFLQN TAFEPEIRIN 130 PKRLKNNNLS RVQES

References

[1]

"The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes." Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R. J. Bacteriol. 188:7922-7931(2006) [PubMed: 16980466] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000099 Genomic DNA. Translation: AAZ71415.1.
RefSeq	YP_305995.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q469M7.
Genome annotation databases
GeneID	3625695.
GenomeReviews	Gene locus Mbar_A2502 in contig CP000099_GR.
KEGG	mba:Mbar_A2502.
NMPDR	fig|269797.3.peg.2890.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q469M7.
OMA	RINGKRA.
Enzyme and pathway databases
BioCyc	MBAR269797:MBAR_A2502-MON.
Family and domain databases
HAMAP	MF_00755. [Tree]
InterPro	IPR016434. RNase_P_comp-2. IPR002759. RNase_P_related. [Graphical view]
Pfam	PF01900. RNase_P_Rpp14. 1 hit. [Graphical view]
PIRSF	PIRSF004952. RNase_P_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP2_METBF

Accession

Primary (citable) accession number: Q469M7

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	September 13, 2005
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)