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Q469A3

- CAPPA_METBF

UniProt

Q469A3 - CAPPA_METBF

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Methanosarcina barkeri (strain Fusaro / DSM 804)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciMBAR269797:GHUW-2682-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Mbar_A2632
OrganismiMethanosarcina barkeri (strain Fusaro / DSM 804)
Taxonomic identifieri269797 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanosarcina
ProteomesiUP000008156: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 526526Phosphoenolpyruvate carboxylasePRO_0000309603Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi269797.Mbar_A2632.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000009826.
KOiK01595.
OMAiDEYMPDY.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q469A3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRKTVFPKV MCTQHPDSAS KYIATQEEPG EAIEAAQIFG CDEYMPDYEG
60 70 80 90 100
KATPYHQNVQ VVSKFIEETD LIPGKDIIIT PRAPSAVQEN QFRQLMVMMS
110 120 130 140 150
IAEANYNALE YSDVQAINEF VHPMTDSVRE IIGAQQHMVD VSELAKKEFG
160 170 180 190 200
FSMEVPCIIP LIEDAPALLH AKELAENTLF AWKGHFGTVP DKFRVFLGKS
210 220 230 240 250
DSALSFGHVA STLSCKYAIN GICELNSELD TQTGIIFGAG TLPFRGHLDL
260 270 280 290 300
MNAENFFKEY RGVGTITLQS ALRYSHKKGD AESLVKLAKA RLPETPELFS
310 320 330 340 350
AEEKEEIINL IGIFGASYSR IIRQLAPTIN RIADLLPQQR DRLMHKGTGG
360 370 380 390 400
YSRSAPDISG LVNLCRTDIG KELEASMPAE DLQLPRAIKF TGALYSIGLP
410 420 430 440 450
PEFIGTGRAL EEAREKLGEA ACENLLTKYF PSLAGDLNFA SEYLDLNVAS
460 470 480 490 500
RFLSSECLKE VSKDLDILHG AFALETSPEP SYRILVEMMQ PDLLQAGSRG
510 520
NCMDEEVSQL VCSTLTKMGK IRKALG
Length:526
Mass (Da):58,068
Last modified:September 13, 2005 - v1
Checksum:iA08490FAE19B6E42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ71539.1.
RefSeqiWP_011307580.1. NC_007355.1.
YP_306119.1. NC_007355.1.

Genome annotation databases

EnsemblBacteriaiAAZ71539; AAZ71539; Mbar_A2632.
GeneIDi3625651.
KEGGimba:Mbar_A2632.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000099 Genomic DNA. Translation: AAZ71539.1 .
RefSeqi WP_011307580.1. NC_007355.1.
YP_306119.1. NC_007355.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 269797.Mbar_A2632.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAZ71539 ; AAZ71539 ; Mbar_A2632 .
GeneIDi 3625651.
KEGGi mba:Mbar_A2632.

Phylogenomic databases

eggNOGi COG1892.
HOGENOMi HOG000009826.
KOi K01595.
OMAi DEYMPDY.

Enzyme and pathway databases

BioCyci MBAR269797:GHUW-2682-MONOMER.

Family and domain databases

HAMAPi MF_01904. PEPcase_type2.
InterProi IPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF14010. PEPcase_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF006677. UCP006677. 1 hit.
SUPFAMi SSF51621. SSF51621. 1 hit.
TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The Methanosarcina barkeri genome: comparative analysis with Methanosarcina acetivorans and Methanosarcina mazei reveals extensive rearrangement within methanosarcinal genomes."
    Maeder D.L., Anderson I., Brettin T.S., Bruce D.C., Gilna P., Han C.S., Lapidus A., Metcalf W.W., Saunders E., Tapia R., Sowers K.R.
    J. Bacteriol. 188:7922-7931(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Fusaro / DSM 804.

Entry informationi

Entry nameiCAPPA_METBF
AccessioniPrimary (citable) accession number: Q469A3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: September 13, 2005
Last modified: November 26, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3