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Protein

Probable glucarate transporter

Gene

gudP

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Uptake of D-glucarate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transport

Enzyme and pathway databases

BioCyciEcoCyc:B2789-MONOMER.
ECOL316407:JW2760-MONOMER.
MetaCyc:B2789-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucarate transporter
Alternative name(s):
D-glucarate permease
Gene namesi
Name:gudP
Synonyms:ygcZ
Ordered Locus Names:b2789, JW2760
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13169. gudP.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2020PeriplasmicSequence analysisAdd
BLAST
Transmembranei21 – 4121HelicalSequence analysisAdd
BLAST
Topological domaini42 – 5817CytoplasmicSequence analysisAdd
BLAST
Transmembranei59 – 7921HelicalSequence analysisAdd
BLAST
Topological domaini80 – 9718PeriplasmicSequence analysisAdd
BLAST
Transmembranei98 – 11821HelicalSequence analysisAdd
BLAST
Topological domaini119 – 15335CytoplasmicSequence analysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence analysisAdd
BLAST
Topological domaini175 – 1762PeriplasmicSequence analysis
Transmembranei177 – 19721HelicalSequence analysisAdd
BLAST
Topological domaini198 – 25457CytoplasmicSequence analysisAdd
BLAST
Transmembranei255 – 27521HelicalSequence analysisAdd
BLAST
Topological domaini276 – 29015PeriplasmicSequence analysisAdd
BLAST
Transmembranei291 – 31121HelicalSequence analysisAdd
BLAST
Topological domaini312 – 32918CytoplasmicSequence analysisAdd
BLAST
Transmembranei330 – 35021HelicalSequence analysisAdd
BLAST
Topological domaini351 – 3511PeriplasmicSequence analysis
Transmembranei352 – 37221HelicalSequence analysisAdd
BLAST
Topological domaini373 – 38715CytoplasmicSequence analysisAdd
BLAST
Transmembranei388 – 40821HelicalSequence analysisAdd
BLAST
Topological domaini409 – 4168PeriplasmicSequence analysis
Transmembranei417 – 43721HelicalSequence analysisAdd
BLAST
Topological domaini438 – 45013CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: GO_Central
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450Probable glucarate transporterPRO_0000121385Add
BLAST

Proteomic databases

PaxDbiQ46916.
PRIDEiQ46916.

Interactioni

Protein-protein interaction databases

BioGridi4263242. 14 interactions.
STRINGi511145.b2789.

Structurei

3D structure databases

ProteinModelPortaliQ46916.
SMRiQ46916. Positions 18-443.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiQ46916.
KOiK03535.
OMAiHHVYLWL.
PhylomeDBiQ46916.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR000849. Sugar_P_transporter.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PIRSFiPIRSF002808. Hexose_phosphate_transp. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46916-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLSQAASS VEKRTNARYW IVVMLFIVTS FNYGDRATLS IAGSEMAKDI
60 70 80 90 100
GLDPVGMGYV FSAFSWAYVI GQIPGGWLLD RFGSKRVYFW SIFIWSMFTL
110 120 130 140 150
LQGFVDIFSG FGIIVALFTL RFLVGLAEAP SFPGNSRIVA AWFPAQERGT
160 170 180 190 200
AVSIFNSAQY FATVIFAPIM GWLTHEVGWS HVFFFMGGLG IVISFIWLKV
210 220 230 240 250
IHEPNQHPGV NKKELEYIAA GGALINMDQQ NTKVKVPFSV KWGQIKQLLG
260 270 280 290 300
SRMMIGVYIG QYCINALTYF FITWFPVYLV QARGMSILKA GFVASVPAVC
310 320 330 340 350
GFIGGVLGGI ISDWLMRRTG SLNIARKTPI VMGMLLSMVM VFCNYVNVEW
360 370 380 390 400
MIIGFMALAF FGKGIGALGW AVMADTAPKE ISGLSGGLFN MFGNISGIVT
410 420 430 440 450
PIAIGYIVGT TGSFNGALIY VGVHALIAVL SYLVLVGDIK RIELKPVAGQ
Length:450
Mass (Da):49,142
Last modified:November 1, 1996 - v1
Checksum:iE0599FACCB1BB488
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA. Translation: AAB40439.1.
U00096 Genomic DNA. Translation: AAC75831.1.
AP009048 Genomic DNA. Translation: BAE76861.1.
PIRiA65061.
RefSeqiNP_417269.1. NC_000913.3.
WP_000097072.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75831; AAC75831; b2789.
BAE76861; BAE76861; BAE76861.
GeneIDi947265.
KEGGiecj:JW2760.
eco:b2789.
PATRICi32120994. VBIEscCol129921_2889.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29581 Genomic DNA. Translation: AAB40439.1.
U00096 Genomic DNA. Translation: AAC75831.1.
AP009048 Genomic DNA. Translation: BAE76861.1.
PIRiA65061.
RefSeqiNP_417269.1. NC_000913.3.
WP_000097072.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ46916.
SMRiQ46916. Positions 18-443.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263242. 14 interactions.
STRINGi511145.b2789.

Proteomic databases

PaxDbiQ46916.
PRIDEiQ46916.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75831; AAC75831; b2789.
BAE76861; BAE76861; BAE76861.
GeneIDi947265.
KEGGiecj:JW2760.
eco:b2789.
PATRICi32120994. VBIEscCol129921_2889.

Organism-specific databases

EchoBASEiEB2961.
EcoGeneiEG13169. gudP.

Phylogenomic databases

eggNOGiENOG4105DJB. Bacteria.
ENOG410XPWC. LUCA.
HOGENOMiHOG000113642.
InParanoidiQ46916.
KOiK03535.
OMAiHHVYLWL.
PhylomeDBiQ46916.

Enzyme and pathway databases

BioCyciEcoCyc:B2789-MONOMER.
ECOL316407:JW2760-MONOMER.
MetaCyc:B2789-MONOMER.

Miscellaneous databases

PROiQ46916.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR004744. Dgal_transporter.
IPR011701. MFS.
IPR020846. MFS_dom.
IPR000849. Sugar_P_transporter.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PIRSFiPIRSF002808. Hexose_phosphate_transp. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00893. 2A0114. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGUDP_ECOLI
AccessioniPrimary (citable) accession number: Q46916
Secondary accession number(s): Q2MA45
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.