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Protein

Putative electron transfer flavoprotein subunit YgcR

Gene

ygcR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

May play a role in a redox process.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Transport

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

BioCyciEcoCyc:G7436-MONOMER.
ECOL316407:JW5441-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative electron transfer flavoprotein subunit YgcR
Gene namesi
Name:ygcR
Ordered Locus Names:b2770, JW5441
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13125. ygcR.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Disruption phenotypei

Cells undergo an apoptotic-like death upon DNA damage characterized by membrane depolarization.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001679001 – 259Putative electron transfer flavoprotein subunit YgcRAdd BLAST259

Proteomic databases

EPDiQ46908.
PaxDbiQ46908.
PRIDEiQ46908.

Interactioni

Subunit structurei

YgcQ and YgcR form a heterodimer.Curated

Protein-protein interaction databases

BioGridi4262284. 16 interactors.
IntActiQ46908. 2 interactors.
STRINGi511145.b2770.

Structurei

3D structure databases

ProteinModelPortaliQ46908.
SMRiQ46908.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ETF beta-subunit/FixA family.Curated

Phylogenomic databases

eggNOGiENOG4106IKH. Bacteria.
COG2086. LUCA.
HOGENOMiHOG000124113.
InParanoidiQ46908.
OMAiQEVRMNI.
PhylomeDBiQ46908.

Family and domain databases

CDDicd01714. ETF_beta. 1 hit.
Gene3Di3.40.50.620. 1 hit.
InterProiIPR014730. ETF_a/b_N.
IPR012255. ETF_b.
IPR033948. ETF_beta_N.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR21294. PTHR21294. 1 hit.
PfamiPF01012. ETF. 1 hit.
[Graphical view]
PIRSFiPIRSF000090. Beta-ETF. 1 hit.
SMARTiSM00893. ETF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46908-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNILLAFKAE PDAGMLAEKE WQAAAQGKSG PDISLLRSLL GADEQAAAAL
60 70 80 90 100
LLAQRKNGTP MSLTALSMGD ERALHWLRYL MALGFEEAVL LETAADLRFA
110 120 130 140 150
PEFVARHIAE WQHQNPLDLI ITGCQSSEGQ NGQTPFLLAE MLGWPCFTQV
160 170 180 190 200
ERFTLDALFI TLEQRTEHGL RCCRVRLPAV IAVRQCGEVA LPVPGMRQRM
210 220 230 240 250
AAGKAEIIRK TVAAEMPAMQ CLQLARAEQR RGATLIDGQT VAEKAQKLWQ

DYLRQRMQP
Length:259
Mass (Da):28,720
Last modified:November 1, 1997 - v2
Checksum:iDB8E1E7203E79E84
GO

Sequence cautioni

The sequence AAA69280 differs from that shown. Reason: Frameshift at position 232.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29579 Genomic DNA. Translation: AAA69280.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75812.2.
AP009048 Genomic DNA. Translation: BAE76847.1.
PIRiF65058.
RefSeqiNP_417250.4. NC_000913.3.
WP_001299652.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75812; AAC75812; b2770.
BAE76847; BAE76847; BAE76847.
GeneIDi947240.
KEGGiecj:JW5441.
eco:b2770.
PATRICi32120952. VBIEscCol129921_2868.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U29579 Genomic DNA. Translation: AAA69280.1. Frameshift.
U00096 Genomic DNA. Translation: AAC75812.2.
AP009048 Genomic DNA. Translation: BAE76847.1.
PIRiF65058.
RefSeqiNP_417250.4. NC_000913.3.
WP_001299652.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ46908.
SMRiQ46908.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262284. 16 interactors.
IntActiQ46908. 2 interactors.
STRINGi511145.b2770.

Proteomic databases

EPDiQ46908.
PaxDbiQ46908.
PRIDEiQ46908.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75812; AAC75812; b2770.
BAE76847; BAE76847; BAE76847.
GeneIDi947240.
KEGGiecj:JW5441.
eco:b2770.
PATRICi32120952. VBIEscCol129921_2868.

Organism-specific databases

EchoBASEiEB2926.
EcoGeneiEG13125. ygcR.

Phylogenomic databases

eggNOGiENOG4106IKH. Bacteria.
COG2086. LUCA.
HOGENOMiHOG000124113.
InParanoidiQ46908.
OMAiQEVRMNI.
PhylomeDBiQ46908.

Enzyme and pathway databases

BioCyciEcoCyc:G7436-MONOMER.
ECOL316407:JW5441-MONOMER.

Miscellaneous databases

PROiQ46908.

Family and domain databases

CDDicd01714. ETF_beta. 1 hit.
Gene3Di3.40.50.620. 1 hit.
InterProiIPR014730. ETF_a/b_N.
IPR012255. ETF_b.
IPR033948. ETF_beta_N.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR21294. PTHR21294. 1 hit.
PfamiPF01012. ETF. 1 hit.
[Graphical view]
PIRSFiPIRSF000090. Beta-ETF. 1 hit.
SMARTiSM00893. ETF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYGCR_ECOLI
AccessioniPrimary (citable) accession number: Q46908
Secondary accession number(s): Q2MA59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 30, 2016
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.