Q46866 (YGIV_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable transcriptional regulator YgiV

Gene names

Name:	ygiV
Ordered Locus Names:	b3023, JW5502

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Function

Represses expression of mcbR. Ref.4

Ontologies

Keywords
Biological process	Transcription Transcription regulation
Molecular function	Repressor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	DNA binding Inferred from direct assay Ref.4. Source: EcoCyc sequence-specific DNA binding transcription factor activity Inferred from direct assay Ref.4. Source: EcoCyc
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	Probable transcriptional regulator YgiV		PRO_0000201333
Experimental info
	Sequence conflict	104 – 105	2	HV → QL in AAA69191. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q46866 [UniParc]. Last modified October 11, 2004. Version 2. Checksum: EEF5A02CBF2DCCF4	FASTA	160	17,827
	10 20 30 40 50 60 MTNLTLDVNI IDFPSIPVAM LPHRCSPELL NYSVAKFIMW RKETGLSPVN QSQTFGVAWD 70 80 90 100 110 120 DPATTAPEAF RFDICGSVSE PIPDNRYGVS NGELTGGRYA VARHVGELDD ISHTVWGIIR 130 140 150 160 HWLPASGEKM RKAPILFHYT NLAEGVTEQR LETDVYVPLA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[2]	"Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005." Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R., Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T., Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H., Thomson N.R., Wishart D., Wanner B.L. Nucleic Acids Res. 34:1-9(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SEQUENCE REVISION TO 104-105.
[3]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]	"Escherichia coli transcription factor YncC (McbR) regulates colanic acid and biofilm formation by repressing expression of periplasmic protein YbiM (McbA)." Zhang X.-S., Garcia-Contreras R., Wood T.K. ISME J. 2:615-631(2008) [PubMed] [Europe PMC] [Abstract] Cited for: FUNCTION. Strain: K12 / BW25113.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U28377 Genomic DNA. Translation: AAA69191.1. U00096 Genomic DNA. Translation: AAT48162.1. AP009048 Genomic DNA. Translation: BAE77079.1.
PIR	E65089.
RefSeq	YP_026197.1. NC_000913.2. YP_491215.1. NC_007779.1.
3D structure databases
ProteinModelPortal	Q46866.
SMR	Q46866. Positions 6-159.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b3023.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAT48162; AAT48162; b3023. BAE77079; BAE77079; BAE77079.
GeneID	12930254. 945805.
KEGG	ecj:Y75_p2949. eco:b3023.
PATRIC	32121458. VBIEscCol129921_3116.
Organism-specific databases
EchoBASE	EB2842.
EcoGene	EG13024. ygiV.
Phylogenomic databases
eggNOG	COG3449.
HOGENOM	HOG000125024.
KO	K07471.
OMA	PVPDNRY.
ProtClustDB	CLSK880552.
Enzyme and pathway databases
BioCyc	EcoCyc:G7573-MONOMER. ECOL316407:JW5502-MONOMER.
Gene expression databases
Genevestigator	Q46866.
Family and domain databases
InterPro	IPR010499. AraC_E-bd. IPR011256. Reg_factor_effector_bac. [Graphical view]
Pfam	PF06445. GyrI-like. 1 hit. [Graphical view]
SMART	SM00871. AraC_E_bind. 1 hit. [Graphical view]
SUPFAM	SSF55136. Bac_reg_effector. 1 hit.
ProtoNet	Search...

Entry information

Entry name

YGIV_ECOLI

Accession

Primary (citable) accession number: Q46866
Secondary accession number(s): Q2M9H7, Q6BF52

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 27, 2002
Last sequence update:	October 11, 2004
Last modified:	May 1, 2013
This is version 82 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program