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Protein

UPF0313 protein YgiQ

Gene

ygiQ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterCuratedNote: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi386Iron-sulfur (4Fe-4S-S-AdoMet)Sequence analysis1
Metal bindingi390Iron-sulfur (4Fe-4S-S-AdoMet)Sequence analysis1
Metal bindingi393Iron-sulfur (4Fe-4S-S-AdoMet)Sequence analysis1

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciEcoCyc:G7568-MONOMER.
ECOL316407:JW5501-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0313 protein YgiQ
Gene namesi
Name:ygiQ
Synonyms:ygiR
Ordered Locus Names:b4469, JW5501
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13019. ygiQ.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000763831 – 739UPF0313 protein YgiQAdd BLAST739

Proteomic databases

PaxDbiQ46861.
PRIDEiQ46861.

Interactioni

Protein-protein interaction databases

BioGridi4260933. 21 interactors.
DIPiDIP-12224N.
IntActiQ46861. 1 interactor.
STRINGi511145.b4469.

Structurei

3D structure databases

ProteinModelPortaliQ46861.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0313 family.Curated

Phylogenomic databases

eggNOGiENOG4105CCT. Bacteria.
COG1032. LUCA.
HOGENOMiHOG000230440.
InParanoidiQ46861.
OMAiNLNTDHS.
PhylomeDBiQ46861.

Family and domain databases

Gene3Di3.80.30.20. 1 hit.
HAMAPiMF_01251. UPF0313. 1 hit.
InterProiIPR006638. Elp3/MiaB/NifB.
IPR020612. Methylthiotransferase_CS.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
IPR022946. UPF0313.
IPR024560. UPF0313_C.
IPR013704. UPF0313_N.
[Graphical view]
PfamiPF11842. DUF3362. 1 hit.
PF04055. Radical_SAM. 1 hit.
PF08497. Radical_SAM_N. 1 hit.
[Graphical view]
SMARTiSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03904. SAM_YgiQ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46861-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSISLIQPD RDLFSWPQYW AACFGPAPFL PMSREEMDQL GWDSCDIILV
60 70 80 90 100
TGDAYVDHPS FGMAICGRML EAQGFRVGII AQPDWSSKDD FMRLGKPNLF
110 120 130 140 150
FGVTAGNMDS MINRYTADRR LRHDDAYTPD NVAGKRPDRA TLVYTQRCKE
160 170 180 190 200
AWKDVPVILG GIEASLRRTA HYDYWSDTVR RSVLVDSKAD MLMFGNGERP
210 220 230 240 250
LVEVAHRLAM GEPISEIRDV RNTAIIVKEA LPGWSGVDST RLDTPGKIDP
260 270 280 290 300
IPHPYGEDLP CADNKPVAPK KQEAKAVTVQ PPRPKPWEKT YVLLPSFEKV
310 320 330 340 350
KGDKVLYAHA SRILHHETNP GCARALMQKH GDRYVWINPP AIPLSTEEMD
360 370 380 390 400
SVFALPYKRV PHPAYGNARI PAYEMIRFSV NIMRGCFGGC SFCSITEHEG
410 420 430 440 450
RIIQSRSEDS IINEIEAIRD TVPGFTGVIS DLGGPTANMY MLRCKSPRAE
460 470 480 490 500
QTCRRLSCVY PDICPHMDTN HEPTINLYRR ARDLKGIKKI LIASGVRYDI
510 520 530 540 550
AVEDPRYIKE LATHHVGGYL KIAPEHTEEG PLSKMMKPGM GSYDRFKELF
560 570 580 590 600
DTYSKQAGKE QYLIPYFISA HPGTRDEDMV NLALWLKKHR FRLDQVQNFY
610 620 630 640 650
PSPLANSTTM YYTGKNPLAK IGYKSEDVFV PKGDKQRRLH KALLRYHDPA
660 670 680 690 700
NWPLIRQALE AMGKKHLIGS RRDCLVPAPT IEEMREARRQ NRNTRPALTK
710 720 730
HTPMATQRQT PATAKKASST QSRPVNAGAK KRPKAAVGR
Length:739
Mass (Da):83,478
Last modified:November 23, 2004 - v3
Checksum:iF85248757612026B
GO

Sequence cautioni

The sequence AAA69183 differs from that shown. Reason: Frameshift at position 321.Curated
The sequence AAA69184 differs from that shown. Reason: Frameshift at position 321.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69183.1. Frameshift.
U28377 Genomic DNA. Translation: AAA69184.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48161.1.
AP009048 Genomic DNA. Translation: BAE77072.1.
RefSeqiWP_000095187.1. NZ_LN832404.1.
YP_026196.1. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAT48161; AAT48161; b4469.
BAE77072; BAE77072; BAE77072.
GeneIDi948963.
KEGGiecj:JW5501.
eco:b4469.
PATRICi32121446. VBIEscCol129921_3110.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69183.1. Frameshift.
U28377 Genomic DNA. Translation: AAA69184.1. Frameshift.
U00096 Genomic DNA. Translation: AAT48161.1.
AP009048 Genomic DNA. Translation: BAE77072.1.
RefSeqiWP_000095187.1. NZ_LN832404.1.
YP_026196.1. NC_000913.3.

3D structure databases

ProteinModelPortaliQ46861.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4260933. 21 interactors.
DIPiDIP-12224N.
IntActiQ46861. 1 interactor.
STRINGi511145.b4469.

Proteomic databases

PaxDbiQ46861.
PRIDEiQ46861.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT48161; AAT48161; b4469.
BAE77072; BAE77072; BAE77072.
GeneIDi948963.
KEGGiecj:JW5501.
eco:b4469.
PATRICi32121446. VBIEscCol129921_3110.

Organism-specific databases

EchoBASEiEB2838.
EcoGeneiEG13019. ygiQ.

Phylogenomic databases

eggNOGiENOG4105CCT. Bacteria.
COG1032. LUCA.
HOGENOMiHOG000230440.
InParanoidiQ46861.
OMAiNLNTDHS.
PhylomeDBiQ46861.

Enzyme and pathway databases

BioCyciEcoCyc:G7568-MONOMER.
ECOL316407:JW5501-MONOMER.

Miscellaneous databases

PROiQ46861.

Family and domain databases

Gene3Di3.80.30.20. 1 hit.
HAMAPiMF_01251. UPF0313. 1 hit.
InterProiIPR006638. Elp3/MiaB/NifB.
IPR020612. Methylthiotransferase_CS.
IPR007197. rSAM.
IPR023404. rSAM_horseshoe.
IPR022946. UPF0313.
IPR024560. UPF0313_C.
IPR013704. UPF0313_N.
[Graphical view]
PfamiPF11842. DUF3362. 1 hit.
PF04055. Radical_SAM. 1 hit.
PF08497. Radical_SAM_N. 1 hit.
[Graphical view]
SMARTiSM00729. Elp3. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03904. SAM_YgiQ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYGIQ_ECOLI
AccessioniPrimary (citable) accession number: Q46861
Secondary accession number(s): Q2M9I4, Q46862, Q6BF53
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 23, 2004
Last modified: November 2, 2016
This is version 113 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.