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Protein

Uncharacterized HTH-type transcriptional regulator YqhC

Gene

yqhC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi229 – 24820H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • positive regulation of transcription, DNA-templated Source: EcoCyc
  • transcription, DNA-templated Source: EcoCyc
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7563-MONOMER.
ECOL316407:JW5849-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized HTH-type transcriptional regulator YqhC
Gene namesi
Name:yqhC
Ordered Locus Names:b3010, JW5849
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13013. yqhC.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 318318Uncharacterized HTH-type transcriptional regulator YqhCPRO_0000194618Add
BLAST

Proteomic databases

PaxDbiQ46855.
PRIDEiQ46855.

Interactioni

Protein-protein interaction databases

BioGridi4262379. 27 interactions.
IntActiQ46855. 6 interactions.
STRINGi511145.b3010.

Structurei

3D structure databases

ProteinModelPortaliQ46855.
SMRiQ46855. Positions 225-305.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105CF7. Bacteria.
ENOG410XRKV. LUCA.
HOGENOMiHOG000203204.
InParanoidiQ46855.
OMAiMYQPGIV.
PhylomeDBiQ46855.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR009594. Tscrpt_reg_HTH_AraC_N.
[Graphical view]
PfamiPF06719. AraC_N. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46855-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQNCAQSNC RIIPKKLRDM KREEICRLLA DKVNKLKNKE NSLSGLLPDV
60 70 80 90 100
RLLYGETPFA RTPVMYEPGI IILFSGHKIG YINERVFRYD ANEYLLLTVP
110 120 130 140 150
LPFECETYAT SEVPLAGLRL NVDILQLQEL LMDIGEDEHF QPSMAASGIN
160 170 180 190 200
SATLSEEILC AAERLLDVME RPLDARILGK QIIREILYYV LTGPCGGALL
210 220 230 240 250
ALVSRQTHFS LISRVLKRIE NKYTENLSVE QLAAEANMSV SAFHHNFKSV
260 270 280 290 300
TSTSPLQYLK NYRLHKARMM IIHDGMKASA AAMRVGYESA SQFSREFKRY
310
FGVTPGEDAA RMRAMQGN
Length:318
Mass (Da):35,957
Last modified:May 30, 2000 - v2
Checksum:i87D5307551EF2D03
GO

Sequence cautioni

The sequence AAA69177 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69177.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76046.2.
AP009048 Genomic DNA. Translation: BAE77067.1.
PIRiH65087.
RefSeqiNP_417483.2. NC_000913.3.

Genome annotation databases

EnsemblBacteriaiAAC76046; AAC76046; b3010.
BAE77067; BAE77067; BAE77067.
GeneIDi947491.
KEGGiecj:JW5849.
eco:b3010.
PATRICi32121434. VBIEscCol129921_3104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69177.1. Different initiation.
U00096 Genomic DNA. Translation: AAC76046.2.
AP009048 Genomic DNA. Translation: BAE77067.1.
PIRiH65087.
RefSeqiNP_417483.2. NC_000913.3.

3D structure databases

ProteinModelPortaliQ46855.
SMRiQ46855. Positions 225-305.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262379. 27 interactions.
IntActiQ46855. 6 interactions.
STRINGi511145.b3010.

Proteomic databases

PaxDbiQ46855.
PRIDEiQ46855.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76046; AAC76046; b3010.
BAE77067; BAE77067; BAE77067.
GeneIDi947491.
KEGGiecj:JW5849.
eco:b3010.
PATRICi32121434. VBIEscCol129921_3104.

Organism-specific databases

EchoBASEiEB2833.
EcoGeneiEG13013. yqhC.

Phylogenomic databases

eggNOGiENOG4105CF7. Bacteria.
ENOG410XRKV. LUCA.
HOGENOMiHOG000203204.
InParanoidiQ46855.
OMAiMYQPGIV.
PhylomeDBiQ46855.

Enzyme and pathway databases

BioCyciEcoCyc:G7563-MONOMER.
ECOL316407:JW5849-MONOMER.

Miscellaneous databases

PROiQ46855.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR009594. Tscrpt_reg_HTH_AraC_N.
[Graphical view]
PfamiPF06719. AraC_N. 1 hit.
PF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYQHC_ECOLI
AccessioniPrimary (citable) accession number: Q46855
Secondary accession number(s): Q2M9I9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: May 30, 2000
Last modified: September 7, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.