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Protein

Putative type II secretion system C-type protein YghF

Gene

yghF

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein uncertaini

Functioni

Might be involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.Curated

GO - Molecular functioni

  1. protein transporter activity Source: InterPro

GO - Biological processi

  1. protein secretion by the type II secretion system Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7537-MONOMER.
ECOL316407:JW5484-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type II secretion system C-type protein YghF
Alternative name(s):
Putative general secretion pathway C-type protein YghF
Gene namesi
Name:yghF
Ordered Locus Names:b2970, JW5484
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG12990. yghF.

Subcellular locationi

Periplasm Curated

GO - Cellular componenti

  1. periplasmic space Source: UniProtKB-SubCell
  2. type II protein secretion system complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence AnalysisAdd
BLAST
Chaini25 – 288264Putative type II secretion system C-type protein YghFPRO_0000013096Add
BLAST

Proteomic databases

PRIDEiQ46834.

Expressioni

Gene expression databases

GenevestigatoriQ46834.

Interactioni

Protein-protein interaction databases

DIPiDIP-12204N.
IntActiQ46834. 1 interaction.
STRINGi316407.yghF.

Structurei

3D structure databases

ProteinModelPortaliQ46834.
SMRiQ46834. Positions 79-143, 180-273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP C family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG3031.
HOGENOMiHOG000124892.
InParanoidiQ46834.
KOiK02452.
OMAiIANRGKQ.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001478. PDZ.
IPR001639. T2SS_protein-C.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
TIGRFAMsiTIGR01713. typeII_sec_gspC. 1 hit.
PROSITEiPS01141. T2SP_C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q46834-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MFWLMLLIIS AKMAHSLWRY ISFSAEYTAV SQPVNKPSRV DAKTFDKNDV
60 70 80 90 100
QLISQQNWFG KYQPVAAQVK QPEPVPVAET RLNVVLRGIA FGARPGAVIE
110 120 130 140 150
EGGKQQVYLQ GETLGSHNAV IEEINRDHVM LRYQGKIERL SLAEEERSTV
160 170 180 190 200
AVTNKKAVSD EAKQAVAEPA VSVPVEIPAA VRQALAKDPQ KIFNYIQLTP
210 220 230 240 250
VRKEGIVGYA AKPGADRSLF DASGFKEGDI AIALNQQDFT DPRAMIALMR
260 270 280
QLPSMDSIQL TVLRKGARHD ISIALRYRLF CPPYWKKS
Length:288
Mass (Da):32,120
Last modified:November 1, 1996 - v1
Checksum:iF1750A8BEB4DC6AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69137.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE77031.1.
PIRiH65082.
RefSeqiYP_491167.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiBAE77031; BAE77031; BAE77031.
GeneIDi12932902.
KEGGiecj:Y75_p2899.
PATRICi48665382. VBIEscCol107702_3000.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69137.1.
U00096 Genomic DNA. No translation available.
AP009048 Genomic DNA. Translation: BAE77031.1.
PIRiH65082.
RefSeqiYP_491167.1. NC_007779.1.

3D structure databases

ProteinModelPortaliQ46834.
SMRiQ46834. Positions 79-143, 180-273.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-12204N.
IntActiQ46834. 1 interaction.
STRINGi316407.yghF.

Proteomic databases

PRIDEiQ46834.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE77031; BAE77031; BAE77031.
GeneIDi12932902.
KEGGiecj:Y75_p2899.
PATRICi48665382. VBIEscCol107702_3000.

Organism-specific databases

EchoBASEiEB2814.
EcoGeneiEG12990. yghF.

Phylogenomic databases

eggNOGiCOG3031.
HOGENOMiHOG000124892.
InParanoidiQ46834.
KOiK02452.
OMAiIANRGKQ.

Enzyme and pathway databases

BioCyciEcoCyc:G7537-MONOMER.
ECOL316407:JW5484-MONOMER.

Gene expression databases

GenevestigatoriQ46834.

Family and domain databases

Gene3Di2.30.42.10. 1 hit.
InterProiIPR001478. PDZ.
IPR001639. T2SS_protein-C.
[Graphical view]
SUPFAMiSSF50156. SSF50156. 1 hit.
TIGRFAMsiTIGR01713. typeII_sec_gspC. 1 hit.
PROSITEiPS01141. T2SP_C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYGHF_ECOLI
AccessioniPrimary (citable) accession number: Q46834
Secondary accession number(s): Q2M9M5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.