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Protein

Putative type II secretion system M-type protein YghD

Gene

yghD

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7535-MONOMER.
ECOL316407:JW2935-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type II secretion system M-type protein YghD
Short name:
Putative T2SS M-type protein YghD
Alternative name(s):
Putative extracytoplasmic function protein C
Putative general secretion pathway M-type protein YghD
Gene namesi
Name:yghD
Synonyms:ecfC
Ordered Locus Names:b2968, JW2935
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12988. yghD.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 39CytoplasmicSequence analysisAdd BLAST39
Transmembranei40 – 60HelicalSequence analysisAdd BLAST21
Topological domaini61 – 178PeriplasmicSequence analysisAdd BLAST118

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002073291 – 178Putative type II secretion system M-type protein YghDAdd BLAST178

Proteomic databases

PaxDbiQ46832.
PRIDEiQ46832.

Interactioni

Protein-protein interaction databases

BioGridi4262353. 1187 interactors.
STRINGi511145.b2968.

Structurei

3D structure databases

ProteinModelPortaliQ46832.
SMRiQ46832.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP M family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105U1E. Bacteria.
COG3149. LUCA.
HOGENOMiHOG000124859.
InParanoidiQ46832.
KOiK02462.
OMAiPQGNKIQ.

Family and domain databases

Gene3Di3.30.1360.100. 1 hit.
InterProiIPR007690. T2SS_M.
IPR023229. T2SS_M_periplasmic.
[Graphical view]
PfamiPF04612. T2SSM. 1 hit.
[Graphical view]
PIRSFiPIRSF006291. GspM. 1 hit.
SUPFAMiSSF103054. SSF103054. 1 hit.

Sequencei

Sequence statusi: Complete.

Q46832-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRDKFIHYF QQWRERQLSR GEHWLAQHLA GRSPREKGML LAAVVFLFSV
60 70 80 90 100
GYYVLIWQPL SERIEQQETI LQQLVAMNTR LKNAAPDIIA ARKSATTTPA
110 120 130 140 150
QVSRVISDSA SAHSVVIRRI ADRGENIQVW IEPVVFNDLL KWLNALDEKY
160 170
ALRVTQIDVS AAEKPGMVNV QRLEFGRG
Length:178
Mass (Da):20,395
Last modified:November 1, 1996 - v1
Checksum:i18822CED9B5BF022
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69135.1.
U00096 Genomic DNA. Translation: AAC76004.1.
AP009048 Genomic DNA. Translation: BAE77030.1.
PIRiF65082.
RefSeqiNP_417442.1. NC_000913.3.
WP_000942785.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76004; AAC76004; b2968.
BAE77030; BAE77030; BAE77030.
GeneIDi947025.
KEGGiecj:JW2935.
eco:b2968.
PATRICi32121352. VBIEscCol129921_3063.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28377 Genomic DNA. Translation: AAA69135.1.
U00096 Genomic DNA. Translation: AAC76004.1.
AP009048 Genomic DNA. Translation: BAE77030.1.
PIRiF65082.
RefSeqiNP_417442.1. NC_000913.3.
WP_000942785.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ46832.
SMRiQ46832.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262353. 1187 interactors.
STRINGi511145.b2968.

Proteomic databases

PaxDbiQ46832.
PRIDEiQ46832.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76004; AAC76004; b2968.
BAE77030; BAE77030; BAE77030.
GeneIDi947025.
KEGGiecj:JW2935.
eco:b2968.
PATRICi32121352. VBIEscCol129921_3063.

Organism-specific databases

EchoBASEiEB2812.
EcoGeneiEG12988. yghD.

Phylogenomic databases

eggNOGiENOG4105U1E. Bacteria.
COG3149. LUCA.
HOGENOMiHOG000124859.
InParanoidiQ46832.
KOiK02462.
OMAiPQGNKIQ.

Enzyme and pathway databases

BioCyciEcoCyc:G7535-MONOMER.
ECOL316407:JW2935-MONOMER.

Miscellaneous databases

PROiQ46832.

Family and domain databases

Gene3Di3.30.1360.100. 1 hit.
InterProiIPR007690. T2SS_M.
IPR023229. T2SS_M_periplasmic.
[Graphical view]
PfamiPF04612. T2SSM. 1 hit.
[Graphical view]
PIRSFiPIRSF006291. GspM. 1 hit.
SUPFAMiSSF103054. SSF103054. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYGHD_ECOLI
AccessioniPrimary (citable) accession number: Q46832
Secondary accession number(s): Q2M9M6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.