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Protein

Uncharacterized protein YgfT

Gene

ygfT

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

[4Fe-4S] clusterBy similarityNote: Binds 4 [4Fe-4S] clusters. May potentially bind 2 additional iron-sulfur clusters.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi12Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi15Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi18Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi22Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi56Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi59Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi64Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi68Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi87Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi90Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi93Iron-sulfur 4 (4Fe-4S)By similarity1
Metal bindingi97Iron-sulfur 3 (4Fe-4S)By similarity1
Metal bindingi112Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi115Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi125Iron-sulfur 2 (4Fe-4S)By similarity1
Metal bindingi129Iron-sulfur 1 (4Fe-4S)By similarity1
Metal bindingi210Iron-sulfurSequence analysis1
Metal bindingi213Iron-sulfurSequence analysis1
Metal bindingi219Iron-sulfurSequence analysis1
Metal bindingi223Iron-sulfurSequence analysis1
Metal bindingi258Iron-sulfurSequence analysis1
Metal bindingi262Iron-sulfurSequence analysis1
Metal bindingi268Iron-sulfurSequence analysis1
Metal bindingi272Iron-sulfurSequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Ligand4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7506-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YgfT
Gene namesi
Name:ygfT
Ordered Locus Names:b2887, JW5469
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13070 ygfT

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001708021 – 639Uncharacterized protein YgfTAdd BLAST639

Proteomic databases

PaxDbiQ46820
PRIDEiQ46820

Interactioni

Protein-protein interaction databases

BioGridi4262335, 15 interactors
DIPiDIP-12175N
STRINGi316385.ECDH10B_3061

Structurei

3D structure databases

ProteinModelPortaliQ46820
SMRiQ46820
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 324Fe-4S ferredoxin-type 1PROSITE-ProRule annotationAdd BLAST30
Domaini47 – 784Fe-4S ferredoxin-type 2PROSITE-ProRule annotationAdd BLAST32
Domaini78 – 1074Fe-4S ferredoxin-type 3PROSITE-ProRule annotationAdd BLAST30
Domaini110 – 1394Fe-4S ferredoxin-type 4PROSITE-ProRule annotationAdd BLAST30
Domaini201 – 2354Fe-4S ferredoxin-type 5PROSITE-ProRule annotationAdd BLAST35

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105BZ8 Bacteria
COG0493 LUCA
COG1142 LUCA
HOGENOMiHOG000031439
InParanoidiQ46820
OMAiHEKQCEG
PhylomeDBiQ46820

Family and domain databases

Gene3Di1.10.1060.10, 1 hit
3.50.50.60, 3 hits
InterProiView protein in InterPro
IPR017896 4Fe4S_Fe-S-bd
IPR017900 4Fe4S_Fe_S_CS
IPR028261 DPD_II
IPR036188 FAD/NAD-bd_sf
IPR023753 FAD/NAD-binding_dom
IPR006006 Glut_synth_ssu2
IPR009051 Helical_ferredxn
PfamiView protein in Pfam
PF13247 Fer4_11, 1 hit
PF14691 Fer4_20, 1 hit
PF07992 Pyr_redox_2, 1 hit
TIGRFAMsiTIGR01318 gltD_gamma_fam, 1 hit
PROSITEiView protein in PROSITE
PS00198 4FE4S_FER_1, 1 hit
PS51379 4FE4S_FER_2, 5 hits

Sequencei

Sequence statusi: Complete.

Q46820-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKFIAAEAA ECIGCHACEI ACAVAHNQEN WPLSHSDFRP RIHVVGKGQA
60 70 80 90 100
ANPVACHHCN NAPCVTACPV NALTFQSDSV QLDEQKCIGC KRCAIACPFG
110 120 130 140 150
VVEMVDTIAQ KCDLCNQRSS GTQACIEVCP TQALRLMDDK GLQQIKVARQ
160 170 180 190 200
RKTAAGKASS DAQPSRSAAL LPVNSRKGAD KISASERKTH FGEIYCGLDP
210 220 230 240 250
QQATYESDRC VYCAEKANCN WHCPLHNAIP DYIRLVQEGK IIEAAELCHQ
260 270 280 290 300
TSSLPEICGR VCPQDRLCEG ACTLKDHSGA VSIGNLERYI TDTALAMGWR
310 320 330 340 350
PDVSKVVPRS EKVAVIGAGP AGLGCADILA RAGVQVDVFD RHPEIGGMLT
360 370 380 390 400
FGIPPFKLDK TVLSQRREIF TAMGIDFHLN CEIGRDITFS DLTSEYDAVF
410 420 430 440 450
IGVGTYGMMR ADLPHEDAPG VIQALPFLTA HTRQLMGLPE SEEYPLTDVE
460 470 480 490 500
GKRVVVLGGG DTTMDCLRTS IRLNAASVTC AYRRDEVSMP GSRKEVVNAR
510 520 530 540 550
EEGVEFQFNV QPQYIACDED GRLTAVGLIR TAMGEPGPDG RRRPRPVAGS
560 570 580 590 600
EFELPADVLI MAFGFQAHAM PWLQGSGIKL DKWGLIQTGD VGYLPTQTHL
610 620 630
KKVFAGGDAV HGADLVVTAM AAGRQAARDM LTLFDTKAS
Length:639
Mass (Da):69,089
Last modified:December 15, 1998 - v2
Checksum:i3B2B96621835655C
GO

Sequence cautioni

The sequence AAA83068 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA Translation: AAA83068.1 Different initiation.
U00096 Genomic DNA Translation: AAC75925.2
AP009048 Genomic DNA Translation: BAE76952.1
PIRiG65072
RefSeqiNP_417363.2, NC_000913.3
WP_001350545.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75925; AAC75925; b2887
BAE76952; BAE76952; BAE76952
GeneIDi949018
KEGGiecj:JW5469
eco:b2887
PATRICifig|1411691.4.peg.3848

Entry informationi

Entry nameiYGFT_ECOLI
AccessioniPrimary (citable) accession number: Q46820
Secondary accession number(s): Q2M9V4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: December 15, 1998
Last modified: March 28, 2018
This is version 134 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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