Q46819 (YGFS_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative electron transport protein YgfS

Gene names

Name:	ygfS
Ordered Locus Names:	b2886, JW5468

Organism

Escherichia coli (strain K12) [Reference proteome] [HAMAP]

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	162 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Sequence similarities	Contains 4 4Fe-4S ferredoxin-type domains.
Sequence caution	The sequence AAA83067.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Biological process	Electron transport Transport
Domain	Repeat
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 162	162	Putative electron transport protein YgfS		PRO_0000159305
Regions
	Domain	3 – 32	30	4Fe-4S ferredoxin-type 1
	Domain	45 – 77	33	4Fe-4S ferredoxin-type 2
	Domain	77 – 106	30	4Fe-4S ferredoxin-type 3
	Domain	110 – 143	34	4Fe-4S ferredoxin-type 4
Sites
	Metal binding	12	1	Iron-sulfur 1 (4Fe-4S) By similarity
	Metal binding	15	1	Iron-sulfur 1 (4Fe-4S) By similarity
	Metal binding	18	1	Iron-sulfur 1 (4Fe-4S) By similarity
	Metal binding	22	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	55	1	Iron-sulfur 3 (4Fe-4S) By similarity
	Metal binding	58	1	Iron-sulfur 3 (4Fe-4S) By similarity
	Metal binding	63	1	Iron-sulfur 3 (4Fe-4S) By similarity
	Metal binding	67	1	Iron-sulfur 4 (4Fe-4S) By similarity
	Metal binding	86	1	Iron-sulfur 4 (4Fe-4S) By similarity
	Metal binding	89	1	Iron-sulfur 4 (4Fe-4S) By similarity
	Metal binding	92	1	Iron-sulfur 4 (4Fe-4S) By similarity
	Metal binding	96	1	Iron-sulfur 3 (4Fe-4S) By similarity
	Metal binding	117	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	120	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	129	1	Iron-sulfur 2 (4Fe-4S) By similarity
	Metal binding	133	1	Iron-sulfur 1 (4Fe-4S) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q46819 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: 22F20225873708A0	FASTA	162	17,513
	10 20 30 40 50 60 MKSLIIVNPA DCIGCRTCEV ACVVAHPSEQ ELNADVFLPR LKVQRLDSIS APVMCHQCEN 70 80 90 100 110 120 APCVGACPVG ALTMGEQVVQ TNSARCIGCQ SCVSACPFGM ITIQSLPGDT RQQIVKCDLC 130 140 150 160 EQREEGPACV ESCPTQALQL LTERELRRVR QQRIVASGEN PL

References

[1]

"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.

[2]

"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U28375 Genomic DNA. Translation: AAA83067.1. Different initiation. U00096 Genomic DNA. Translation: AAC75924.2. AP009048 Genomic DNA. Translation: BAE76951.1.
PIR	F65072.
RefSeq	NP_417362.4. NC_000913.2. YP_491087.1. NC_007779.1.
3D structure databases
ProteinModelPortal	Q46819.
SMR	Q46819. Positions 12-135.
ModBase	Search...
Protein-protein interaction databases
STRING	511145.b2886.
Proteomic databases
PRIDE	Q46819.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC75924; AAC75924; b2886. BAE76951; BAE76951; BAE76951.
GeneID	12930235. 949016.
KEGG	ecj:Y75_p2818. eco:b2886.
PATRIC	32121180. VBIEscCol129921_2978.
Organism-specific databases
EchoBASE	EB2880.
EcoGene	EG13069. ygfS.
Phylogenomic databases
eggNOG	COG1142.
HOGENOM	HOG000163385.
OMA	ACALAHT.
ProtClustDB	CLSK880521.
Enzyme and pathway databases
BioCyc	EcoCyc:G7505-MONOMER. ECOL316407:JW5468-MONOMER.
Gene expression databases
Genevestigator	Q46819.
Family and domain databases
InterPro	IPR001450. 4Fe4S-bd_dom. IPR017896. 4Fe4S_Fe-S-bd. IPR017900. 4Fe4S_Fe_S_CS. [Graphical view]
Pfam	PF00037. Fer4. 1 hit. PF12798. Fer4_3. 1 hit. PF12800. Fer4_4. 1 hit. [Graphical view]
PROSITE	PS00198. 4FE4S_FER_1. 1 hit. PS51379. 4FE4S_FER_2. 4 hits. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

YGFS_ECOLI

Accession

Primary (citable) accession number: Q46819
Secondary accession number(s): Q2M9V5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	May 30, 2000
Last modified:	May 1, 2013
This is version 90 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program