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Protein

Uncharacterized protein YgfK

Gene

ygfK

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi901 – 9011Iron-sulfur 1 (4Fe-4S)Sequence analysis
Metal bindingi905 – 9051Iron-sulfur 1 (4Fe-4S)Sequence analysis
Metal bindingi908 – 9081Iron-sulfur 1 (4Fe-4S)Sequence analysis
Metal bindingi912 – 9121Iron-sulfur 2 (4Fe-4S)Sequence analysis
Metal bindingi938 – 9381Iron-sulfur 2 (4Fe-4S)Sequence analysis
Metal bindingi941 – 9411Iron-sulfur 2 (4Fe-4S)Sequence analysis
Metal bindingi944 – 9441Iron-sulfur 2 (4Fe-4S)Sequence analysis
Metal bindingi948 – 9481Iron-sulfur 1 (4Fe-4S)Sequence analysis

GO - Molecular functioni

  • 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  • iron ion binding Source: EcoCyc
  • oxidoreductase activity Source: EcoCyc
Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7497-MONOMER.
ECOL316407:JW5923-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YgfK
Gene namesi
Name:ygfK
Ordered Locus Names:b2878, JW5923
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13061. ygfK.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 10321032Uncharacterized protein YgfKPRO_0000201329Add
BLAST

Proteomic databases

EPDiQ46811.
PaxDbiQ46811.
PRIDEiQ46811.

Interactioni

Protein-protein interaction databases

BioGridi4262325. 19 interactions.
DIPiDIP-28091N.
IntActiQ46811. 2 interactions.
STRINGi511145.b2878.

Structurei

3D structure databases

ProteinModelPortaliQ46811.
SMRiQ46811. Positions 441-849, 895-970.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini928 – 958314Fe-4S ferredoxin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 4Fe-4S ferredoxin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105BZ8. Bacteria.
COG0493. LUCA.
HOGENOMiHOG000277437.
KOiK12527.
OMAiEVCPNRA.
OrthoDBiEOG6XSZQF.

Family and domain databases

Gene3Di3.20.20.70. 3 hits.
3.50.50.60. 3 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR013785. Aldolase_TIM.
IPR028261. DPD_II.
IPR023753. FAD/NAD-binding_dom.
IPR009051. Helical_ferredxn.
IPR017701. Se_rdtase_YgfK.
[Graphical view]
PfamiPF14691. Fer4_20. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF46548. SSF46548. 2 hits.
TIGRFAMsiTIGR03315. Se_ygfK. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46811-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGDIMRPIPF EELLTRIFDE YQQQRSIFGI PEQQFYSPVK GKTVSVFGET
60 70 80 90 100
CATPVGPAAG PHTQLAQNIV TSWLTGGRFI ELKTVQILDR LELEKPCIDA
110 120 130 140 150
EDECFNTEWS TEFTLLKAWD EYLKAWFALH LLEAMFQPSD SGKSFIFNMS
160 170 180 190 200
VGYNLEGIKQ PPMQQFIDNM MDASDHPKFA QYRDTLNKLL QDDAFLARHG
210 220 230 240 250
LQEKRESLQA LPARIPTSMV HGVTLSTMHG CPPHEIEAIC RYMLEEKGLN
260 270 280 290 300
TFVKLNPTLL GYARVREILD VCGFGYIGLK EESFDHDLKL TQALEMLERL
310 320 330 340 350
MALAKEKSLG FGVKLTNTLG TINNKGALPG EEMYMSGRAL FPLSINVAAV
360 370 380 390 400
LSRAFDGKLP ISYSGGASQL TIRDIFDTGI RPITMATDLL KPGGYLRLSA
410 420 430 440 450
CMRELEGSDA WGLDHVDVER LNRLAADALT MEYTQKHWKP EERIEVAEDL
460 470 480 490 500
PLTDCYVAPC VTACAIKQDI PEYIRLLGEH RYADALELIY QRNALPAITG
510 520 530 540 550
HICDHQCQYN CTRLDYDSAL NIRELKKVAL EKGWDEYKQR WHKPAGSGSR
560 570 580 590 600
HPVAVIGAGP AGLAAGYFLA RAGHPVTLFE REANAGGVVK NIIPQFRIPA
610 620 630 640 650
ELIQHDIDFV AAHGVKFEYG CSPDLTIEQL KNQGFHYVLI ATGTDKNSGV
660 670 680 690 700
KLAGDNQNVW KSLPFLREYN KGTALKLGKH VVVVGAGNTA MDCARAALRV
710 720 730 740 750
PGVEKATIVY RRSLQEMPAW REEYEEALHD GVEFRFLNNP ERFDADGTLT
760 770 780 790 800
LRVMSLGEPD EKGRRRPVET NETVTLLVDS LITAIGEQQD TEALNAMGVP
810 820 830 840 850
LDKNGWPDVD HNGETRLTDV FMIGDVQRGP SSIVAAVGTA RRATDAILSR
860 870 880 890 900
ENIRSHQNDK YWNNVNPAEI YQRKGDISIT LVNSDDRDAF VAQEAARCLE
910 920 930 940 950
CNYVCSKCVD VCPNRANVSI AVPGFQNRFQ TLHLDAYCNE CGNCAQFCPW
960 970 980 990 1000
NGKPYKDKIT VFSLAQDFDN SSNPGFLVED CRVRVRLNNQ SWVLNIDSKG
1010 1020 1030
QFNNVPPELN DMCRIISHVH QHHHYLLGRV EV
Length:1,032
Mass (Da):115,582
Last modified:November 1, 1996 - v1
Checksum:i588056B51BE89648
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83059.1.
U00096 Genomic DNA. Translation: AAC75916.1.
AP009048 Genomic DNA. Translation: BAE76944.1.
PIRiF65071.
RefSeqiNP_417354.1. NC_000913.3.
WP_000502395.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75916; AAC75916; b2878.
BAE76944; BAE76944; BAE76944.
GeneIDi949068.
KEGGiecj:JW5923.
eco:b2878.
PATRICi32121166. VBIEscCol129921_2971.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83059.1.
U00096 Genomic DNA. Translation: AAC75916.1.
AP009048 Genomic DNA. Translation: BAE76944.1.
PIRiF65071.
RefSeqiNP_417354.1. NC_000913.3.
WP_000502395.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ46811.
SMRiQ46811. Positions 441-849, 895-970.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262325. 19 interactions.
DIPiDIP-28091N.
IntActiQ46811. 2 interactions.
STRINGi511145.b2878.

Proteomic databases

EPDiQ46811.
PaxDbiQ46811.
PRIDEiQ46811.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75916; AAC75916; b2878.
BAE76944; BAE76944; BAE76944.
GeneIDi949068.
KEGGiecj:JW5923.
eco:b2878.
PATRICi32121166. VBIEscCol129921_2971.

Organism-specific databases

EchoBASEiEB2873.
EcoGeneiEG13061. ygfK.

Phylogenomic databases

eggNOGiENOG4105BZ8. Bacteria.
COG0493. LUCA.
HOGENOMiHOG000277437.
KOiK12527.
OMAiEVCPNRA.
OrthoDBiEOG6XSZQF.

Enzyme and pathway databases

BioCyciEcoCyc:G7497-MONOMER.
ECOL316407:JW5923-MONOMER.

Miscellaneous databases

PROiQ46811.

Family and domain databases

Gene3Di3.20.20.70. 3 hits.
3.50.50.60. 3 hits.
InterProiIPR017896. 4Fe4S_Fe-S-bd.
IPR017900. 4Fe4S_Fe_S_CS.
IPR013785. Aldolase_TIM.
IPR028261. DPD_II.
IPR023753. FAD/NAD-binding_dom.
IPR009051. Helical_ferredxn.
IPR017701. Se_rdtase_YgfK.
[Graphical view]
PfamiPF14691. Fer4_20. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF46548. SSF46548. 2 hits.
TIGRFAMsiTIGR03315. Se_ygfK. 1 hit.
PROSITEiPS00198. 4FE4S_FER_1. 1 hit.
PS51379. 4FE4S_FER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

Entry informationi

Entry nameiYGFK_ECOLI
AccessioniPrimary (citable) accession number: Q46811
Secondary accession number(s): Q2M9W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.