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Protein

Uncharacterized sigma-54-dependent transcriptional regulator YgeV

Gene

ygeV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi300 – 307ATPPROSITE-ProRule annotation8
Nucleotide bindingi364 – 373ATPPROSITE-ProRule annotation10
DNA bindingi567 – 585H-T-H motifBy similarityAdd BLAST19

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation, Two-component regulatory system
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7488-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized sigma-54-dependent transcriptional regulator YgeV
Gene namesi
Name:ygeV
Ordered Locus Names:b2869, JW2837
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13052 ygeV

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000813801 – 592Uncharacterized sigma-54-dependent transcriptional regulator YgeVAdd BLAST592

Proteomic databases

PaxDbiQ46802
PRIDEiQ46802

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi4261521, 20 interactors
DIPiDIP-12157N
IntActiQ46802, 15 interactors
STRINGi316385.ECDH10B_3044

Structurei

3D structure databases

ProteinModelPortaliQ46802
SMRiQ46802
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 229PASPROSITE-ProRule annotationAdd BLAST72
Domaini272 – 502Sigma-54 factor interactionPROSITE-ProRule annotationAdd BLAST231

Phylogenomic databases

eggNOGiENOG4108JUB Bacteria
COG3829 LUCA
HOGENOMiHOG000058487
InParanoidiQ46802
OMAiMIENMDQ
PhylomeDBiQ46802

Family and domain databases

CDDicd00130 PAS, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR009057 Homeobox-like_sf
IPR002197 HTH_Fis
IPR027417 P-loop_NTPase
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR002078 Sigma_54_int
IPR025662 Sigma_54_int_dom_ATP-bd_1
IPR025943 Sigma_54_int_dom_ATP-bd_2
IPR025944 Sigma_54_int_dom_CS
PfamiView protein in Pfam
PF02954 HTH_8, 1 hit
PF13188 PAS_8, 1 hit
PF00158 Sigma54_activat, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00091 PAS, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
SSF52540 SSF52540, 1 hit
SSF55785 SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50112 PAS, 1 hit
PS00675 SIGMA54_INTERACT_1, 1 hit
PS00676 SIGMA54_INTERACT_2, 1 hit
PS00688 SIGMA54_INTERACT_3, 1 hit
PS50045 SIGMA54_INTERACT_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q46802-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELATTQSVL MQIQPTIQRF ARMLASVLQL EVEIVDENLC RVAGTGAYGK
60 70 80 90 100
FLGRQLSGNS RLLRHVLETK TEKVVTQSRF DPLCEGCDSK ENCREKAFLG
110 120 130 140 150
TPVILQDRCV GVISLIAVTH EQQEHISDNL REFSDYVRHI STIFVSKLLE
160 170 180 190 200
DQGPGDNISK IFATMIDNMD QGVLVVDDEN RVQFVNQTAL KTLGVVQNNI
210 220 230 240 250
IGKPIRFRPL TFESNFTHGH MQHIVSWDDK SELIIGQLHN IQGRQLFLMA
260 270 280 290 300
FHQSHTSFSV ANAPDEPHIE QLVGECRVMR QLKRLISRIA PSPSSVMVVG
310 320 330 340 350
ESGTGKEVVA RAIHKLSGRR NKPFIAINCA AIPEQLLESE LFGYVKGAFT
360 370 380 390 400
GASANGKTGL IQAANTGTLF LDEIGDMPLM LQAKLLRAIE AREILPIGAS
410 420 430 440 450
SPIQVDIRII SATNQNLAQF IAEGKFREDL FYRLNVIPIT LPPLRERQED
460 470 480 490 500
IELLVHYFLH LHTRRLGSVY PGIAPDVVEI LRKHRWPGNL RELSNLMEYL
510 520 530 540 550
VNVVPSGEVI DSTLLPPNLL NNGTTEQSDV TEVSEAHLSL DDAGGTALEE
560 570 580 590
MEKQMIREAL SRHNSKKQVA DELGIGIATL YRKIKKYELL NT
Length:592
Mass (Da):66,096
Last modified:November 1, 1996 - v1
Checksum:i7FA13B60A4AB9DDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA Translation: AAA83050.1
U00096 Genomic DNA Translation: AAC75907.1
AP009048 Genomic DNA Translation: BAE76935.1
PIRiE65070
RefSeqiNP_417345.1, NC_000913.3
WP_000417791.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC75907; AAC75907; b2869
BAE76935; BAE76935; BAE76935
GeneIDi947320
KEGGiecj:JW2837
eco:b2869
PATRICifig|1411691.4.peg.3865

Similar proteinsi

Entry informationi

Entry nameiYGEV_ECOLI
AccessioniPrimary (citable) accession number: Q46802
Secondary accession number(s): Q2M9X1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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