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Protein

Uncharacterized sigma-54-dependent transcriptional regulator YgeV

Gene

ygeV

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi300 – 307ATPPROSITE-ProRule annotation8
Nucleotide bindingi364 – 373ATPPROSITE-ProRule annotation10
DNA bindingi567 – 585H-T-H motifBy similarityAdd BLAST19

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation, Two-component regulatory system

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciEcoCyc:G7488-MONOMER.
ECOL316407:JW2837-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized sigma-54-dependent transcriptional regulator YgeV
Gene namesi
Name:ygeV
Ordered Locus Names:b2869, JW2837
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG13052. ygeV.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000813801 – 592Uncharacterized sigma-54-dependent transcriptional regulator YgeVAdd BLAST592

Proteomic databases

PaxDbiQ46802.
PRIDEiQ46802.

Interactioni

Protein-protein interaction databases

BioGridi4261521. 14 interactors.
DIPiDIP-12157N.
IntActiQ46802. 14 interactors.
MINTiMINT-1242950.
STRINGi511145.b2869.

Structurei

3D structure databases

ProteinModelPortaliQ46802.
SMRiQ46802.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini158 – 229PASPROSITE-ProRule annotationAdd BLAST72
Domaini272 – 502Sigma-54 factor interactionPROSITE-ProRule annotationAdd BLAST231

Sequence similaritiesi

Contains 1 PAS (PER-ARNT-SIM) domain.PROSITE-ProRule annotation
Contains 1 sigma-54 factor interaction domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108JUB. Bacteria.
COG3829. LUCA.
HOGENOMiHOG000058487.
InParanoidiQ46802.
OMAiMIENMDQ.
PhylomeDBiQ46802.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR029016. GAF_dom-like.
IPR009057. Homeodomain-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR000014. PAS.
IPR002078. Sigma_54_int.
IPR025662. Sigma_54_int_dom_ATP-bd_1.
IPR025943. Sigma_54_int_dom_ATP-bd_2.
IPR025944. Sigma_54_int_dom_CS.
[Graphical view]
PfamiPF02954. HTH_8. 1 hit.
PF13188. PAS_8. 1 hit.
PF00158. Sigma54_activat. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55785. SSF55785. 1 hit.
PROSITEiPS50112. PAS. 1 hit.
PS00675. SIGMA54_INTERACT_1. 1 hit.
PS00676. SIGMA54_INTERACT_2. 1 hit.
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q46802-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELATTQSVL MQIQPTIQRF ARMLASVLQL EVEIVDENLC RVAGTGAYGK
60 70 80 90 100
FLGRQLSGNS RLLRHVLETK TEKVVTQSRF DPLCEGCDSK ENCREKAFLG
110 120 130 140 150
TPVILQDRCV GVISLIAVTH EQQEHISDNL REFSDYVRHI STIFVSKLLE
160 170 180 190 200
DQGPGDNISK IFATMIDNMD QGVLVVDDEN RVQFVNQTAL KTLGVVQNNI
210 220 230 240 250
IGKPIRFRPL TFESNFTHGH MQHIVSWDDK SELIIGQLHN IQGRQLFLMA
260 270 280 290 300
FHQSHTSFSV ANAPDEPHIE QLVGECRVMR QLKRLISRIA PSPSSVMVVG
310 320 330 340 350
ESGTGKEVVA RAIHKLSGRR NKPFIAINCA AIPEQLLESE LFGYVKGAFT
360 370 380 390 400
GASANGKTGL IQAANTGTLF LDEIGDMPLM LQAKLLRAIE AREILPIGAS
410 420 430 440 450
SPIQVDIRII SATNQNLAQF IAEGKFREDL FYRLNVIPIT LPPLRERQED
460 470 480 490 500
IELLVHYFLH LHTRRLGSVY PGIAPDVVEI LRKHRWPGNL RELSNLMEYL
510 520 530 540 550
VNVVPSGEVI DSTLLPPNLL NNGTTEQSDV TEVSEAHLSL DDAGGTALEE
560 570 580 590
MEKQMIREAL SRHNSKKQVA DELGIGIATL YRKIKKYELL NT
Length:592
Mass (Da):66,096
Last modified:November 1, 1996 - v1
Checksum:i7FA13B60A4AB9DDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83050.1.
U00096 Genomic DNA. Translation: AAC75907.1.
AP009048 Genomic DNA. Translation: BAE76935.1.
PIRiE65070.
RefSeqiNP_417345.1. NC_000913.3.
WP_000417791.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75907; AAC75907; b2869.
BAE76935; BAE76935; BAE76935.
GeneIDi947320.
KEGGiecj:JW2837.
eco:b2869.
PATRICi32121148. VBIEscCol129921_2962.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U28375 Genomic DNA. Translation: AAA83050.1.
U00096 Genomic DNA. Translation: AAC75907.1.
AP009048 Genomic DNA. Translation: BAE76935.1.
PIRiE65070.
RefSeqiNP_417345.1. NC_000913.3.
WP_000417791.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliQ46802.
SMRiQ46802.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261521. 14 interactors.
DIPiDIP-12157N.
IntActiQ46802. 14 interactors.
MINTiMINT-1242950.
STRINGi511145.b2869.

Proteomic databases

PaxDbiQ46802.
PRIDEiQ46802.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75907; AAC75907; b2869.
BAE76935; BAE76935; BAE76935.
GeneIDi947320.
KEGGiecj:JW2837.
eco:b2869.
PATRICi32121148. VBIEscCol129921_2962.

Organism-specific databases

EchoBASEiEB2864.
EcoGeneiEG13052. ygeV.

Phylogenomic databases

eggNOGiENOG4108JUB. Bacteria.
COG3829. LUCA.
HOGENOMiHOG000058487.
InParanoidiQ46802.
OMAiMIENMDQ.
PhylomeDBiQ46802.

Enzyme and pathway databases

BioCyciEcoCyc:G7488-MONOMER.
ECOL316407:JW2837-MONOMER.

Miscellaneous databases

PROiQ46802.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.30.450.40. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR029016. GAF_dom-like.
IPR009057. Homeodomain-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR000014. PAS.
IPR002078. Sigma_54_int.
IPR025662. Sigma_54_int_dom_ATP-bd_1.
IPR025943. Sigma_54_int_dom_ATP-bd_2.
IPR025944. Sigma_54_int_dom_CS.
[Graphical view]
PfamiPF02954. HTH_8. 1 hit.
PF13188. PAS_8. 1 hit.
PF00158. Sigma54_activat. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF55785. SSF55785. 1 hit.
PROSITEiPS50112. PAS. 1 hit.
PS00675. SIGMA54_INTERACT_1. 1 hit.
PS00676. SIGMA54_INTERACT_2. 1 hit.
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYGEV_ECOLI
AccessioniPrimary (citable) accession number: Q46802
Secondary accession number(s): Q2M9X1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 134 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.